16,403 research outputs found
Sealed containers in Z
Physical means of securing information, such as sealed envelopes and scratch cards, can be used to achieve cryptographic objectives. Reasoning about this has so far been informal.
We give a model of distinguishable sealed envelopes in Z, exploring design decisions and further analysis and development of such models
The Porphyromonas gingivalis hemagglutinins HagB and HagC are major mediators of adhesion and biofilm formation
Porphyromonas gingivalis is a bacterium associated with chronic periodontitis that possesses a family of genes encoding hemagglutinins required for heme acquisition. In this study we generated ΔhagB and ΔhagC mutants in strain W83 and demonstrate that both hagB and hagC are required for adherence to oral epithelial cells. Unexpectedly, a double ΔhagB/ΔhagC mutant had less severe adherence defects than either of the single mutants, but was found to exhibit increased expression of the gingipain-encoding genes rgpA and kgp, suggesting that a ΔhagB/ΔhagC mutant is only viable in populations of cells that exhibit increased expression of genes involved in heme acquisition. Disruption of hagB in the fimbriated strain ATCC33277 demonstrated that HagB is also required for stable attachment of fimbriated bacteria to oral epithelial cells. Mutants of hagC were also found to form defective single and multi-species biofilms that had reduced biomass relative to biofilms formed by the wild-type strain. This study highlights the hitherto unappreciated importance of these genes in oral colonization and biofilm formation
Limits on Clouds and Hazes for the TRAPPIST-1 Planets
The TRAPPIST-1 planetary system is an excellent candidate for study of the
evolution and habitability of M-dwarf planets. Transmission spectroscopy
observations performed with the Hubble Space Telescope (HST) suggest the
innermost five planets do not possess clear hydrogen atmospheres. Here we
reassess these conclusions with recently updated mass constraints and expand
the analysis to include limits on metallicity, cloud top pressure, and the
strength of haze scattering. We connect recent laboratory results of particle
size and production rate for exoplanet hazes to a one-dimensional atmospheric
model for TRAPPIST-1 transmission spectra. Doing so, we obtain a
physically-based estimate of haze scattering cross sections. We find haze
scattering cross sections on the order of 1e-26 to 1e-19 cm squared are needed
in hydrogen-rich atmospheres for TRAPPIST-1 d, e, and f to match the HST data.
For TRAPPIST-1 g, we cannot rule out a clear hydrogen-rich atmosphere. We also
modeled the effects an opaque cloud deck and substantial heavy element content
have on the transmission spectra. We determine that hydrogen-rich atmospheres
with high altitude clouds, at pressures of 12mbar and lower, are consistent
with the HST observations for TRAPPIST-1 d and e. For TRAPPIST-1 f and g, we
cannot rule out clear hydrogen-rich cases to high confidence. We demonstrate
that metallicities of at least 60xsolar with tropospheric (0.1 bar) clouds
agree with observations. Additionally, we provide estimates of the precision
necessary for future observations to disentangle degeneracies in cloud top
pressure and metallicity. Our results suggest secondary, volatile-rich
atmospheres for the outer TRAPPIST-1 planets d, e, and f.Comment: 15 pages, 3 figures, 2 tables, accepted in the Astronomical Journa
Polarized Broad H-alpha Emission from the LINER Nucleus of NGC 1052
Optical spectropolarimetry of the nucleus of the LINER NGC 1052, obtained at
the Keck Observatory, reveals a rise in polarization in the wings of the
H-alpha line profile. The polarization vector of H-alpha is offset by 67
degrees from the parsec-scale radio axis and by 83 degrees from the
kiloparsec-scale radio axis, roughly in accord with expectations for scattering
within the opening cone of an obscuring torus. The broad component of H-alpha
has FWHM ~ 2100 km/s in total flux and FWHM ~ 5000 km/s in polarized light.
Scattering by electrons is the mechanism most likely responsible for this
broadening, and we find T_e ~ 10^5 K for the scattering medium, similar to
values observed in Seyfert 2 nuclei. This is the first detection of a polarized
broad emission line in a LINER, demonstrating that unified models of active
galactic nuclei are applicable to at least some LINERs.Comment: 6 pages, 2 figures, prepared using the emulateapj style file,
accepted for publication in The Astrophysical Journal Letter
Electron microscopic and biochemical characterization of Fraction 1 protein
High resolution electron microscopy of Fraction I protein from plant leave
BIOMECHANICS OF RUNNING - Electromyographic Analysis of the Hip during Jogging, Running and Sprinting
The patterns of muscle action during human locomotion have
been investigated for several decades. Lower extremity
electromyographic activity in walking was investigated by Bartholomew and the Prosthetic Research Group at Berkeley in 1953. (1) Others investigated the actions of specific muscles during various leg movements. Basmajian and LeBan et al. (6) examined the electromyographic action of the iliopsoas muscle. These studies have led to the investigation of running. Saito et aI., (10) presented temporal data on the gait cycle of running. James and Brubaker (5) presented a descriptive analysis of running. Other researchers have directed their work toward sprinting: Fenn (4) investigated frictional and kinetic factors in 1930, and Dillman (3) and Ralph Mann (7) used kinetic analysis. Mann and Hagy (9) and Mann et aI. (8) investigated temporal and electromyographic patterns of walking, running and sprinting. This study investigates and describes the electromyographic activity ofthe lower extrJmities and trunk musculature duringjogging, running, and sprinting
Reconciling taxonomy and phylogenetic inference: formalism and algorithms for describing discord and inferring taxonomic roots
Although taxonomy is often used informally to evaluate the results of
phylogenetic inference and find the root of phylogenetic trees, algorithmic
methods to do so are lacking. In this paper we formalize these procedures and
develop algorithms to solve the relevant problems. In particular, we introduce
a new algorithm that solves a "subcoloring" problem for expressing the
difference between the taxonomy and phylogeny at a given rank. This algorithm
improves upon the current best algorithm in terms of asymptotic complexity for
the parameter regime of interest; we also describe a branch-and-bound algorithm
that saves orders of magnitude in computation on real data sets. We also
develop a formalism and an algorithm for rooting phylogenetic trees according
to a taxonomy. All of these algorithms are implemented in freely-available
software.Comment: Version submitted to Algorithms for Molecular Biology. A number of
fixes from previous versio
Statistical analysis of general aviation VG-VGH data
To represent the loads spectra of general aviation aircraft operating in the Continental United States, VG and VGH data collected since 1963 in eight operational categories were processed and analyzed. Adequacy of data sample and current operational categories, and parameter distributions required for valid data extrapolation were studied along with envelopes of equal probability of exceeding the normal load factor (n sub z) versus airspeed for gust and maneuver loads and the probability of exceeding current design maneuver, gust, and landing impact n sub z limits. The significant findings are included
Does online sexually transmitted infection screening compromise care? A service evaluation comparing the management of chlamydial infection diagnosed online and in clinic
Patient demand on sexual health services (SHS) in the UK is so high that many services have introduced online screening to accommodate more patients. There are concerns that these services may not be accessible to all. This service evaluation was undertaken to determine whether online screening is accessible by those patients most at need by comparing the demographics and number of asymptomatic chlamydial infections detected online and in clinic. No difference was found in the age nor level of deprivation, demonstrating that online services are an accessible way to screen for STIs without overburdening established services
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