6,634 research outputs found
The phase transitions in 2D Z(N) vector models for N>4
We investigate both analytically and numerically the renormalization group
equations in 2D Z(N) vector models. The position of the critical points of the
two phase transitions for N>4 is established and the critical index \nu\ is
computed. For N=7, 17 the critical points are located by Monte Carlo
simulations and some of the corresponding critical indices are determined. The
behavior of the helicity modulus is studied for N=5, 7, 17. Using these and
other available Monte Carlo data we discuss the scaling of the critical points
with N and some other open theoretical problems.Comment: 19 pages, 8 figures, 10 tables; version to appear on Phys. Rev.
Murine models of sleep apnea: functional implications of altered macrophage polarity and epigenetic modifications in adipose and vascular tissues
Obstructive sleep apnea (OSA) is a highly prevalent disease across the lifespan, is characterized by chronic intermittent hypoxia and sleep fragmentation, and has been independently associated with substantial cardiometabolic morbidity. However, the reversibility of end-organ morbidity with treatment is not always apparent, suggesting that both tissue remodeling and epigenetic mechanisms may be operationally involved. Here, we review the cumulative evidence focused around murine models of OSA to illustrate the temporal dependencies of cardiometabolic dysfunction and its reversibility, and more particularly to discuss the critical contributions of tissue macrophages to adipose tissue insulin resistance and vascular atherogenesis. In addition, we describe initial findings potentially implicating epigenetic alterations in both the emergence of the cardiometabolic morbidity of OSA, and in its reversibility with treatment. We anticipate that improved understanding of macrophage biology and epigenetics in the context of intermittent hypoxia and sleep fragmentation will lead to discovery of novel therapeutic targets and improved cardiovascular and metabolic outcomes in OSA
Constraining the ages of the fireballs in the wake of the dIrr galaxy VCC1217 / IC3418
A complex of Halpha emitting blobs with strong FUV excess is associated to
the dIrr galaxy VCC1217 / IC3418 (Hester et al. 2010), and extends up to 17 Kpc
in the South-East direction. These outstanding features can be morphologically
divided into diffuse filaments and compact knots, where most of the star
formation activity traced by Halpha takes place. We investigate the properties
of the galaxy and the blobs using a multiwavelength approach in order to
constrain their origin. We collect publicly available data in UV and Halpha and
observe the scene in the optical U,g,r,i bands with LBT. The photometric data
allows to evaluate the star formation rate and to perform a SED fitting
separately of the galaxy and the blobs in order to constrain their stellar
population age. Moreover we analyze the color and luminosity profile of the
galaxy and its spectrum to investigate its recent interaction with the Virgo
cluster. Our analysis confirms that the most plausible mechanism for the
formation of the blobs is ram pressure stripping by the Virgo cluster IGM. The
galaxy colors, luminosity profile and SED are consistent with a sudden gas
depletion in the last few hundred Myr. The SED fitting of the blobs constrains
their ages in < 400 Myr.Comment: 10 pages, 11 figures, accepted for publication in Astronomy and
Astrophysic
Direct and correlated responses to artificial selection on developmental time and wing length in Drosophila buzzatii
Developmental time and body size are two positively correlated traits closely related to fitness in many organisms including Drosophila. Previous work suggested that these two traits are involved in a trade-off that may result from a negative genetic correlation between their effects on pre-adult and adult fitness. Here, we examine the evolution of developmental time and body size (indexed by wing length) under artificial Selection applied to one or both traits in replicated D. buzzatii populations. Directional changes in both developmental time and wing length indicate the presence of substantial additive genetic variance for both traits. The strongest response to selection for fast development was found in lines selected simultaneously to reduce both developmental time and wing length, probably as an expected consequence of a synergistic effect of indirect selection. When selection was applied in the direction opposite to the putative genetic correlation, that is, large wing length but fast development, no responses were observed for developmental time. Lines selected to reduce both wing length and developmental time diverged slightly faster from the control than lines selected to increase wing length and reduce developmental time. However, wing length did not diverge from the control in lines selected only for fast development. These results suggest a complex genetic basis of the correlation between developmental time and wing length, but are generally consistent with the hypothesis that both traits are related in a trade-off. However, we found that this trade-off may disappear under uncrowded conditions, with fast-developing lines exhibiting a higher pre-adult viability than other lines when tested at high larval density.Fil:Norry, F.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Piccinali, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Hasson, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Advances on Testing C-Planarity of Embedded Flat Clustered Graphs
We show a polynomial-time algorithm for testing c-planarity of embedded flat
clustered graphs with at most two vertices per cluster on each face.Comment: Accepted at GD '1
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