85 research outputs found

    Association of maternal body composition and diet on breast milk hormones and neonatal growth during the first month of lactation

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    Introduction: Preterm birth is associated with altered growth patterns and an increased risk of cardiometabolic diseases, with breast milk (BM) being a counteracting factor. Preterm infants also show alterations in adipokines and gut hormones influencing appetite and metabolism. Since these hormones are present in BM, it is possible that their levels may equilibrate deficiencies improving infant growth. We aimed to assess 1) the BM levels of ghrelin, resistin, leptin, insulin, peptide YY, and the gastrointestinal peptide in women with preterm and term labor; 2) the relationship between BM hormones and neonatal growth; and 3) the influence of maternal body composition and diet on these BM hormones. Methods: BM from 48 women (30 term and 18 preterm labor) was collected at days 7, 14, and 28 of lactation. Maternal body composition was evaluated by bioimpedance, and neonate anthropometric parameters were collected from medical records. The maternal dietary pattern was assessed by a 72-h dietary recall at days 7 and 28 of lactation. BM hormones were analyzed by the U-Plex Ultra-sensitive method. Data were analyzed using linear regression models. BM from women with preterm labor had lower ghrelin levels, with the other hormones being significantly higher compared to women with term delivery. Results: In premature infants, growth was positively associated with BM ghrelin, while, in term infants, it was positively associated with insulin and negatively with peptide YY. In the first week of lactation, women with preterm labor had higher body fat compared to women with term labor. In this group, ghrelin levels were positively associated with maternal body fat and with fiber and protein intake. In women with term labor, no associations between anthropometric parameters and BM hormones were found, and fiber intake was negatively associated with peptide YY. Discussion: Preterm labor is a factor influencing the levels of BM adipokines and gut hormones, with BM ghrelin being a relevant hormone for premature infant growth. Since ghrelin is lower in BM from women with preterm labor and the levels are associated with maternal fat storage and some dietary components, our data support the importance to monitor diet and body composition in women who gave birth prematurely to improve the BM hormonal statusThis research was funded by Promotion of Knowledge Transfer program (PTC-2020) from Universidad Autónoma de Madrid in collaboration with Alter Farmacia, SA, Spanish Ministry of Science, and Innovation (RTI2018-097504-B-I00

    Association of maternal body composition and diet on breast milk hormones and neonatal growth during the first month of lactation

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    Preterm birth is associated with altered growth patterns and an increased risk of cardiometabolic diseases, with breast milk (BM) being a counteracting factor. Preterm infants also show alterations in adipokines and gut hormones influencing appetite and metabolism. Since these hormones are present in BM, it is possible that their levels may equilibrate deficiencies improving infant growth. We aimed to assess 1) the BM levels of ghrelin, resistin, leptin, insulin, peptide YY, and the gastrointestinal peptide in women with preterm and term labor; 2) the relationship between BM hormones and neonatal growth; and 3) the influence of maternal body composition and diet on these BM hormone

    Non-coherent MIMO Communication for the 5th Generation Mobile: Overview and Practical Aspects

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    Although there are many theoretical studies on the performance of non-coherent schemes in MIMO systems, their impact on real-world cellular systems is still unknown. This paper focuses on bringing noncoherent techniques into practical systems using CoMP and/or MIMO processing

    Towards User-Centric Operation in 5G Networks

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    © 2016 Monserrat et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.There are three pillars that characterize the new 5G revolution, namely, the use of heterogeneous wireless access technologies conforming an ultra-dense network, the software-driven flexibility of this network, and the simplified and user-centric operation and management of the system. This next-generation network operation and management shall be based on the usage of Big Data Analytics techniques to monitor the end-user quality of experience through direct measures of the network. This paper describes the Astellia approach towards this network revolution and presents some results on the performance of quality estimation techniques in current cellular networks. Thanks to the use of this approach, operators may fill the gap of knowledge between network key performance indicators and user experience. This way, they can operate in a proactive manner and have actual measurements of the users' experience, which leads to a fairer judgement of the users' complaints.The authors would like to thank the funding received from the Ministerio de Industria, Energia y Turismo TSI-100102-2013-106 funds.Monserrat Del Río, JF.; Alepuz Benaches, I.; Cabrejas Peñuelas, J.; Osa Ginés, V.; López Bayo, J.; García-Zarza, R.; Domenech-Benlloch, MJ.... (2016). Towards User-Centric Operation in 5G Networks. EURASIP Journal on Wireless Communications and Networking. 2016(6):1-7. https://doi.org/10.1186/s13638-015-0506-zS1720166J Monserrat et al., Rethinking the mobile and wireless network architecture: the METIS research into 5G, in European Conference on Networks and Communications (EuCNC), 2014, pp. 1–55G-PPP, The 5G Infrastructure Public Private Partnership: the next generation of communication networks and services, 2015. Available at http://5g-ppp.eu/wp-content/uploads/2015/02/5G-Vision-Brochure-v1.pdfJF Monserrat, M Fallgren (eds.), Report on simulation results and evaluations, 2015. ICT-317669 METIS Deliverable 6.5Z Yingxiao, Z Ying Jun, User-centric virtual cell design for Cloud Radio Access Networks, in IEEE Signal Processing Advances in Wireless Communications (SPAWC), 2014, pp. 249–253JF Monserrat, G Mange, V Braun, H Tullberg, G Zimmermann, Ö Bulakci, METIS research advances towards the 5G mobile and wireless system definition. EURASIP. J. Wirel. Commun. Netw. 2015, 53 (2015)F Boccardi, RW Heath, A Lozano, TL Marzetta, P Popovski, Five disruptive technology directions for 5G. IEEE. Commun. Mag. 52(2), 74–80 (2014)P Agyapong, M Iwamura, D Staehle, W Kiess, A Benjebbour, Design considerations for a 5G network architecture. IEEE. Commun. Mag. 52(11), 65–75 (2014)Nokia Siemens Networks, Acquisition and retention white paper, 2013. http://networks.nokia.com/sites/default/files/document/acquisition___retention_white_paper.pdfDZ Yazti, S Krishnaswamy, Mobile big data analytics: research, practice, and opportunities, in IEEE 15th International Conference on Mobile Data Management (MDM), 2014R Kreher, UMTS performance measurement: a practical guide to KPIs for the UTRAN environment (Wiley, Chichester, 2006)S Mehrotra, On the implementation of a primal-dual interior point method. SIAM. J. Optim. 2, 575–601 (1992)V Osa, J Matamales, J Monserrat, J Lopez, Localization in wireless networks: the potential of triangulation techniques. Wirel. Pers. Commun. 68(4), 1525–1538 (2013

    Physical exercise, fitness and dietary pattern and their relationship with circadian blood pressure pattern, augmentation index and endothelial dysfunction biological markers: EVIDENT study protocol

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    Background: Healthy lifestyles may help to delay arterial aging. The purpose of this study is to analyze the relationship of physical activity and dietary pattern to the circadian pattern of blood pressure, central and peripheral blood pressure, pulse wave velocity, carotid intima-media thickness and biological markers of endothelial dysfunction in active and sedentary individuals without arteriosclerotic disease. Methods/Design Design: A cross-sectional multicenter study with six research groups. Subjects: From subjects of the PEPAF project cohort, in which 1,163 who were sedentary became active, 1,942 were sedentary and 2,346 were active. By stratified random sampling, 1,500 subjects will be included, 250 in each group. Primary measurements: We will evaluate height, weight, abdominal circumference, clinical and ambulatory blood pressure with the Radial Pulse Wave Acquisition Device (BPro), central blood pressure and augmentation index with Pulse Wave Application Software (A-Pulse) and SphymgoCor System Px (Pulse Wave Analysis), pulse wave velocity (PWV) with SphymgoCor System Px (Pulse Wave Velocity), nutritional pattern with a food intake frequency questionnaire, physical activity with the 7-day PAR questionnaire and accelerometer (Actigraph GT3X), physical fitness with the cycle ergometer (PWC-170), carotid intima-media thickness by ultrasound (Micromax), and endothelial dysfunction biological markers (endoglin and osteoprotegerin). Discussion: Determining that sustained physical activity and the change from sedentary to active as well as a healthy diet improve circadian pattern, arterial elasticity and carotid intima-media thickness may help to propose lifestyle intervention programs. These interventions could improve the cardiovascular risk profile in some parameters not routinely assessed with traditional risk scales. From the results of this study, interventional approaches could be obtained to delay vascular aging that combine physical exercise and diet

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

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    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
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