Equilibrium shapes of a pair of equal uniform vortices

The shapes and properties of two equal corotating uniform vortices, rotating steadily about each other, are calculated. An integrodifferential equation for the bounding contour is solved numerically, using Newton's method. The results compare well with those obtained from a simple model. It is shown that steady solutions do not exist if the vortices are too close. The stability to two-dimensional disturbances is discussed qualitatively and the critical separation at which the system becomes unstable is calculated. Some comments are made on the stability of a vortex pair of equal counter rotating uniform vortices

Resolved stellar population of distant galaxies in the ELT era

The expected imaging capabilities of future Extremely Large Telescopes (ELTs) will offer the unique possibility to investigate the stellar population of distant galaxies from the photometry of the stars in very crowded fields. Using simulated images and photometric analysis we explore here two representative science cases aimed at recovering the characteristics of the stellar populations in the inner regions of distant galaxies. Specifically: case A) at the center of the disk of a giant spiral in the Centaurus Group, (mu B~21, distance of 4.6 Mpc); and, case B) at half of the effective radius of a giant elliptical in the Virgo Cluster (mu~19.5, distance of 18 Mpc). We generate synthetic frames by distributing model stellar populations and adopting a representative instrumental set up, i.e. a 42 m Telescope operating close to the diffraction limit. The effect of crowding is discussed in detail showing how stars are measured preferentially brighter than they are as the confusion limit is approached. We find that (i) accurate photometry (sigma~0.1, completeness >90%) can be obtained for case B) down to I~28.5, J~27.5 allowing us to recover the stellar metallicity distribution in the inner regions of ellipticals in Virgo to within ~0.1 dex; (ii) the same photometric accuracy holds for the science case A) down to J~28.0, K~27.0, enabling to reconstruct of the star formation history up to the Hubble time via simple star counts in diagnostic boxes. For this latter case we discuss the possibility of deriving more detailed information on the star formation history from the analysis of their Horizontal Branch stars. We show that the combined features of high sensitivity and angular resolution of ELTs may open a new era for our knowledge of the stellar content of galaxies of different morphological type up to the distance of the Virgo cluster.Comment: 21 pages, 17 figures, PASP accepted in pubblicatio

Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins

Kidney Ankyrin Repeat-containing Proteins (KANKs) comprise a family of four evolutionary conserved proteins (KANK1 to 4) that localize to the belt of mature focal adhesions (FAs) where they regulate integrin-mediated adhesion, actomyosin contractility, and link FAs to the cortical microtubule stabilization complex (CMSC). The human KANK proteins were first identified in kidney and have been associated with kidney cancer and nephrotic syndrome. Here, we report the distributions and subcellular localizations of the four Kank mRNAs and proteins in mouse tissues. We found that the KANK family members display distinct and rarely overlapping expression patterns. Whereas KANK1 is expressed at the basal side of epithelial cells of all tissues tested, KANK2 expression is mainly observed at the plasma membrane and/or cytoplasm of mesenchymal cells and KANK3 exclusively in vascular and lymphatic endothelial cells. KANK4 shows the least widespread expression pattern and when present, overlaps with KANK2 in contractile cells, such as smooth muscle cells and pericytes. Our findings show that KANKs are widely expressed in a cell type-specific manner, which suggests that they have cell- and tissue-specific functions

Shoulder posture and median nerve sliding

Background: Patients with upper limb pain often have a slumped sitting position and poorshoulder posture. Pain could be due to poor posture causing mechanical changes (stretch; localpressure) that in turn affect the function of major limb nerves (e.g. median nerve). This studyexamines (1) whether the individual components of slumped sitting (forward head position, trunkflexion and shoulder protraction) cause median nerve stretch and (2) whether shoulderprotraction restricts normal nerve movements.Methods: Longitudinal nerve movement was measured using frame-by-frame cross-correlationanalysis from high frequency ultrasound images during individual components of slumped sitting.The effects of protraction on nerve movement through the shoulder region were investigated byexamining nerve movement in the arm in response to contralateral neck side flexion.Results: Neither moving the head forward or trunk flexion caused significant movement of themedian nerve. In contrast, 4.3 mm of movement, adding 0.7% strain, occurred in the forearm duringshoulder protraction. A delay in movement at the start of protraction and straightening of thenerve trunk provided evidence of unloading with the shoulder flexed and elbow extended and thescapulothoracic joint in neutral. There was a 60% reduction in nerve movement in the arm duringcontralateral neck side flexion when the shoulder was protracted compared to scapulothoracicneutral.Conclusion: Slumped sitting is unlikely to increase nerve strain sufficient to cause changes tonerve function. However, shoulder protraction may place the median nerve at risk of injury, sincenerve movement is reduced through the shoulder region when the shoulder is protracted andother joints are moved. Both altered nerve dynamics in response to moving other joints and localchanges to blood supply may adversely affect nerve function and increase the risk of developingupper quadrant pain

Topological correlations in soap froths

Correlation in two-dimensional soap froth is analysed with an effective potential for the first time. Cells with equal number of sides repel (with linear correlation) while cells with different number of sides attract (with NON-bilinear) for nearest neighbours, which cannot be explained by the maximum entropy argument. Also, the analysis indicates that froth is correlated up to the third shell neighbours at least, contradicting the conventional ideas that froth is not strongly correlated.Comment: 10 Pages LaTeX, 6 Postscript figure

Comparing the reliability of networks by spectral analysis

We provide a method for the ranking of the reliability of two networks with the same connectance. Our method is based on the Cheeger constant linking the topological property of a network with its spectrum. We first analyze a set of twisted rings with the same connectance and degree distribution, and obtain the ranking of their reliability using their eigenvalue gaps. The results are generalized to general networks using the method of rewiring. The success of our ranking method is verified numerically for the IEEE57, the Erd\H{o}s-R\'enyi, and the Small-World networks.Comment: 7 pages, 3 figure

Efficacy and residues of chlorpyrifos applied against root maggots attacking cole crops in British Columbia

Chlorpyrifos proved to be as effective as chlorfenvinphos, and more effective than fensulfothion and diazinon for cabbage maggot control in root and stem crucifers. For short season crops such as cauliflower, broccoli and cabbage, the granular formulation applied at seeding, followed in 21 days with a single drench of the emulsifiable liquid formulation was adequate. In Brussels sprouts, the slowest of the stem crucifers to mature, a minimum of two drench applications were necessary for acceptable control. In rutabaga, another long season crop, chlorpyrifos 15G applied at seeding followed by 3 drench applications (i.e., at 21-day intervals) after seeding was necessary to produce rutabagas with acceptable damage levels at harvest. In the sandy-clay loam where these studies were undertaken, chlorpyrifos applied at the dosage rates and at the times prescribed for the stem and root crucifers studied did not give rise to appreciable residues at harvest. These studies show that a pre-harvest interval of 32 days would be appropriate for the 5 crops studied

Deciphering the contribution of biofilm to the pathogenesis of peritoneal dialysis infections: characterization and microbial behaviour on dialysis fluids

Infections are major complications in peritoneal dialysis (PD) with a multifactorial etiology that comprises patient, microbial and dialytic factors. This study aimed at investigating the contribution of microbial biofilms on PD catheters to recalcitrant infections and their interplay with PD related-factors. A prospective observational study was performed on 47 patients attending Centro Hospitalar of Porto and Vila Nova de Gaia/Espinho to whom the catheter was removed due to infectious (n = 16) and non-infectious causes (n = 31). Microbial density on the catheter was assessed by culture methods and the isolated microorganisms identified by matrix-assisted laser desorption/ionization time-of-flight intact cell mass spectrometry. The effect of conventional and three biocompatible PD solutions on 16 Coagulase Negative Staphylococci (CNS) and 10 Pseudomonas aeruginosa strains planktonic growth and biofilm formation was evaluated. Cultures were positive in 87.5% of the catheters removed due infectious and 90.3% removed due to non-infectious causes. However, microbial yields were higher on the cuffs of catheters removed due to infection vs. non-infection. Staphylococci (CNS and Staphylococcus aureus) and P. aeruginosa were the predominant species: 32% and 20% in the infection and 43.3% and 22.7% in the non-infection group, respectively. In general, PD solutions had a detrimental effect on planktonic CNS and P. aeruginosa strains growth. All strains formed biofilms in the presence of PD solutions. The solutions had a more detrimental effect on P. aeruginosa than CNS strains. No major differences were observed between conventional and biocompatible solutions, although in icodextrin solution biofilm biomass was lower than in bicarbonate/lactate solution. Overall, we show that microbial biofilm is universal in PD catheters with the subclinical menace of Staphylococci and P. aeruginosa. Cuffs colonization may significantly contribute to infection. PD solutions differentially impact microbial species. This knowledge is important for the development of infection diagnosis, treatment and preventive strategies.This work received support from a Sociedade Portuguesa de Nefrologia (http://www.spnefro.pt) research grant to AR and a Fundação para a Ciência e Tecnologia (http://www.fct.pt) post doc grant (SFRH/BPD/73663/2010) to MM. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript