Intoxicação experimental por Ipomoea asarifolia (salsa) em caprinos: achados clínicos, hematológicos e anátomo-patológicos.

Neste estudo foram descritas as funções vitais, os sintomas clínicos, os valores do hemograma e as alterações anátomo-patológicas em caprinos intoxicados experimentalmente pela Ipomoea asarifolia (salsa). Foram utilizados 14 caprinos, sem raça definida (SRD), com idade variando entre 09 e 10 meses dispostos em 3 grupos experimentais. Os grupo I e II foram constituído por 5 animais e o grupo III por 4 animais. Os animais do grupo I receberam a I. asarifolia na quantidade de 0,5% de matéria seca por quilo de peso vivo, diariamente, até a morte. Os do grupo II receberam a mesma quantidade da planta, porém até o 5º dia após o aparecimento dos primeiros sintomas de intoxicação. Os do grupo III serviram como controle e receberam capim elefante (Pennisetum purpureum) na quantidade de 0,5% de matéria seca por quilo de peso vivo. Os sinais clínicos de intoxicação foram observados 24 horas após a administração da I. asarifolia caracterizando-se por balanço lateral da cabeça, tremores musculares, perda do equilíbrio, sonolência, excita ção, ranger dos dentes, gemido, decúbito lateral e prostração. Todos os animais do grupo I morreram intoxicados e, do grupo II, apenas dois animais vieram a óbito. Três animais do grupo II recuperaram-se gradativamente e no 24º dia do experimento não apresentaram sintomas clínicos nem seqüelas. Com base nos achados clínicos, hematológicos e anátomo-patológicos conclui-se que: a I. asarifolia é uma planta tóxica para caprinos e que os sintomas são progressivos e dependem da administração contínua da planta. Clinical symptoms, haematological and pathological disorders in goats intoxicated experimentally with Ipomoea asarifolia (salsa). Abstract - The Ipomoea asariffoilia is a native plant in Northeast of Brazil which goats eat during dry period and lacking of food. In this paper, it described the clinical symptoms, haematological and pathological disorders and vital functions in goats intoxicated experimentally with I. asarifolia. Fourteen animals with age between 9-10 months, breeding SRD was utilized and separated into 3 groups. In group I and II contained 5 animals each and group III (control) 4 animals. In group I goats received 0.5% of I. asarifolia dry material (live weight/kilogram) each day until death. In group II was given the same quantity for 5 days after appearance of intoxication symptoms. In control group, the animals received elephant grass (Pennisetum purpureum). The clinical symptoms observed after 24 hours were head swing to side, muscle tremble, loss of equilibrium, excitation, groan, decubit lateral and prostation. All the goats in group I died with intoxicated symptoms and group II only 2 animals. Three goats that survived were recuperated by day 24. It concluded that an I. asarifolia is a toxic plant for goats with progressive symptoms when there is a continuous administration of that plant

Structural studies of two Tinuvin® P analogs: 2-(2,4-Dimethylphenyl)- 2H-benzotriazole and 2-phenyl-2H-benzotriazole

2-(2,4-Dimethylphenyl)-2H-benzotriazole (1) has been synthesized in a three step procedure starting from 2,4-dimethyl-N-(2-nitrophenyl)benzamide via a 5-(2,4-dimethylphenyl)-1-(2-nitrophenyl)-1H-tetrazole intermediate. Its structure and those of Tinuvin® P and 2-phenyl-2H-benzotriazole (5) have been studied by multinuclear NMR (1H-, 13C- and 15N-) in solution and in the solid state. X-ray diffraction analysis of 1 and 5 allowed to us establish the molecular conformation around the single bond connecting the two aromatic systems, in agreement with the conclusions drawn from the NMR study. In the case of 1 ab initio geometry optimization was achieved at the Hartree-Fock HF/6-31G** and DFT B3LYP/6-31G ** levels. © 2007 by MDPI.Peer Reviewe

Seasonal variation in the prevalence of leptospirosis in stray dogs in the citv of S. Paulo (Brazil)

One thousand, four hundred and twenty-eight sera from stray dogs from the city of S. Paulo were examined using agglutination microscopic testing. Of the total of 1428 sera, 308 (21.6%) showed positive. Seasonal influence was observed in the leptospiral infection of the canine population studied in that the largest number of the reagent sera was verified in the summer (24.2%) and autumn (24.9%). In contrast, spring (18.3%) and winter (18.3%) prevalence levels were lower. These differences were considered significant from the statistical point of view. The canicola serotype was found to be the main cause of leptospirosis in the population examined (50.7%), followed by icterohaemorrhagiae (25.5%), grippetyphosa (7.8%), pomona (67%), and ballum (4.4%).Utilizando a técnica da soroaglutinação microscópica para o diagnóstico de leptospirose, 308 (21,6%) de 1428 soros de cães errantes da cidade de São Paulo (Brasil) mostraram-se reagentes. Na população canina estudada, a infecção leptospirótica sofreu influência sazonal. Verão (24,2%) e outono (24,9%) foram as estações do ano com maior número de soros reatores, em oposição à primavera (18,3%) e inverno (18,3%). Estas diferenças foram significantes, estatisticamente. Ô sorotipo canicola é o principal causador da leptospirose na população estudada (50,7%), seguido do icterohaemorrhagiae (25,5%); grippotyphosa (7,8%); pomona (6,7%) e ballum (4,4%)

U-Pb zircon dating of ash fall deposits from the paleozoic paran? basin of Brazil and Uruguay: A reevaluation of the stratigraphic correlations

Ash fall layers and vitroclastic-carrying sediments distributed throughout the entire Permian stratigraphic range of the Paraná Basin (Brazil and Uruguay) occur in the Tubarão Supergroup (Rio Bonito Formation) and the Passa Dois Group (Irati, Estrada Nova/Teresina, Corumbataí, and Rio do Rasto Formations), which constitute the Gondwana 1 Supersequence. U-Pb zircon ages, acquired by SHRIMP and isotope-dissolution thermal ionization mass spectrometer (IDTIMS) from tuffs within the Mangrullo and Yaguari Formations of Uruguay, are compatible with a correlation with the Irati and parts of the Teresina and Rio do Rasto Formations, respectively, of Brazil. U-Pb zircon ages suggest maximum depositional ages for the samples: (1) Rio Bonito Formation: ages ranging from 295:8 5 3:1 to 304:0 5 5:6 Ma (Asselian, lowermost Permian), consistent with the age range of the Protohaploxypinus goraiensis subzone; (2) Irati Formation: ages ranging from 279:9 5 4:8 to 280:0 5 3:0 Ma (Artinskian, middle Permian), consistent with the occurrence of species of the Lueckisporites virkkiae zone; (3) Rio do Rasto Formation: ages ranging from 266:7 5 5:4 to 274:6 5 6:3Ma (Wordian to Roadian, middle Permian). All the SHRIMP U-Pb zircon ages are consistent with their superimposition order in the stratigraphy, the latest revisions to the Permian timescale (International Commission of Stratigraphy, 2018 version), and the most recent appraisals of biostratigraphic data. The ID-TIMS U-Pb zircon ages from the Corumbataí Formation suggest that U-Pb ages may be 110% younger than interpreted biostratigraphic ages

Geology of the Alarcon Rise, Southern Gulf of California

Meter‐scale AUV bathymetric mapping and ROV sampling of the entire 47 km‐long Alarcon Rise between the Pescadero and Tamayo transforms show that the shallowest inflated portion of the segment hosts all four active hydrothermal vent fields and the youngest, hottest, and highest effusion rate lava flows. This shallowest inflated part is located ∼1/3 of the way between the Tamayo and Pescadero transforms and is paved by a 16 km2 channelized flow that erupted from 9 km of en echelon fissures and is larger than historic flows on the East Pacific Rise or on the Gorda and Juan de Fuca Ridges. Starting ∼5 km south of the Pescadero transform, 6.5 km of the Alarcon Rise is characterized by faulted ridges and domes of fractionated lavas ranging from basaltic andesite to rhyolite with up to 77.3 wt % SiO2. These are the first known rhyolites from the submarine global mid‐ocean ridge system. Silicic lavas range from \u3e11.7 ka, to as young as 1.1 ka. A basalt‐to‐basaltic andesite sequence and an andesite‐to‐dacite‐to‐rhyolite sequence are consistent with crystal fractionation but some intermediate basaltic andesite and andesite formed by mixing basalt with dacite or rhyolite. Magmatism occurred along the bounding Tamayo and Pescadero transforms as extensive channelized flows. The flows erupted from ring faults surrounding uplifted sediment hills inferred to overlie sills. The transforms are transtensional to accommodate magma migration from the adjacent Alarcon Rise

Geology of the Alarcon Rise, Southern Gulf of California

Meter‐scale AUV bathymetric mapping and ROV sampling of the entire 47 km‐long Alarcon Rise between the Pescadero and Tamayo transforms show that the shallowest inflated portion of the segment hosts all four active hydrothermal vent fields and the youngest, hottest, and highest effusion rate lava flows. This shallowest inflated part is located ∼1/3 of the way between the Tamayo and Pescadero transforms and is paved by a 16 km2 channelized flow that erupted from 9 km of en echelon fissures and is larger than historic flows on the East Pacific Rise or on the Gorda and Juan de Fuca Ridges. Starting ∼5 km south of the Pescadero transform, 6.5 km of the Alarcon Rise is characterized by faulted ridges and domes of fractionated lavas ranging from basaltic andesite to rhyolite with up to 77.3 wt % SiO2. These are the first known rhyolites from the submarine global mid‐ocean ridge system. Silicic lavas range from \u3e11.7 ka, to as young as 1.1 ka. A basalt‐to‐basaltic andesite sequence and an andesite‐to‐dacite‐to‐rhyolite sequence are consistent with crystal fractionation but some intermediate basaltic andesite and andesite formed by mixing basalt with dacite or rhyolite. Magmatism occurred along the bounding Tamayo and Pescadero transforms as extensive channelized flows. The flows erupted from ring faults surrounding uplifted sediment hills inferred to overlie sills. The transforms are transtensional to accommodate magma migration from the adjacent Alarcon Rise