FP-tree and COFI Based Approach for Mining of Multiple Level Association Rules in Large Databases

In recent years, discovery of association rules among itemsets in a large database has been described as an important database-mining problem. The problem of discovering association rules has received considerable research attention and several algorithms for mining frequent itemsets have been developed. Many algorithms have been proposed to discover rules at single concept level. However, mining association rules at multiple concept levels may lead to the discovery of more specific and concrete knowledge from data. The discovery of multiple level association rules is very much useful in many applications. In most of the studies for multiple level association rule mining, the database is scanned repeatedly which affects the efficiency of mining process. In this research paper, a new method for discovering multilevel association rules is proposed. It is based on FP-tree structure and uses cooccurrence frequent item tree to find frequent items in multilevel concept hierarchy.Comment: Pages IEEE format, International Journal of Computer Science and Information Security, IJCSIS, Vol. 7 No. 2, February 2010, USA. ISSN 1947 5500, http://sites.google.com/site/ijcsis

Oxidative stress specifically downregulates survivin to promote breast tumour formation.

BackgroundBreast cancer, a heterogeneous disease has been broadly classified into oestrogen receptor positive (ER+) or oestrogen receptor negative (ER-) tumour types. Each of these tumours is dependent on specific signalling pathways for their progression. While high levels of survivin, an anti-apoptotic protein, increases aggressive behaviour in ER- breast tumours, oxidative stress (OS) promotes the progression of ER+ breast tumours. Mechanisms and molecular targets by which OS promotes tumourigenesis remain poorly understood.ResultsDETA-NONOate, a nitric oxide (NO)-donor induces OS in breast cancer cell lines by early re-localisation and downregulation of cellular survivin. Using in vivo models of HMLE(HRAS) xenografts and E2-induced breast tumours in ACI rats, we demonstrate that high OS downregulates survivin during initiation of tumourigenesis. Overexpression of survivin in HMLE(HRAS) cells led to a significant delay in tumour initiation and tumour volume in nude mice. This inverse relationship between survivin and OS was also observed in ER+ human breast tumours. We also demonstrate an upregulation of NADPH oxidase-1 (NOX1) and its activating protein p67, which are novel markers of OS in E2-induced tumours in ACI rats and as well as in ER+ human breast tumours.ConclusionOur data, therefore, suggest that downregulation of survivin could be an important early event by which OS initiates breast tumour formation

Effect of Neemta 2100 toxicity on acetylcholinesterase and serum glutamate oxaloacetate transaminase enzymes in serum of fish, Oreochromis mossambicus

Acetylcholinesterase and serum glutamate oxaloacetate transaminase enzymes have been used as marker monitoring the effect of neem seed based pesticide Neemta 2100 on the fish, Oreochromis mossambicus. Fishes exposed to sublethal concentrations of Neemta 2100 for acute periods of 24 and 48 hours were sacrificed to determine enzyme activities in serum affected due to toxicity. Laboratory studies of in vivo exposure of this pesticide showed synergistic inhibitory effect during acute period of toxicity. Acetylcholinesterase was noticed as 6.25 µm substrate hydrolyzed/mg protein/hour and serum glutamate oxaloacetate transaminase was noticed as 36.71 µm substrate hydrolyzed/mg protein/hour in control fish serum. Significant decrease in GOT level in Neemta 2100 treated fishes after short term exposure indicated its severe toxicity to fish

Economics analysis of tomato cultivation under poly house and open field conditions in Haryana, India

In the present paper an attempt has been made to study the comparative economics of tomato cultivation under poly house and open field conditions in Karnal district, Haryana. Production and marketing constraints under poly house cultivation have also been identified. The primary data for the agriculture year 2013-14 were collected by personal interviews of the selected farmers with the help of a specially designed schedule. Simple statistical tool like Averages and percentages were used to compare, contrast and interpret the results properly. The overall findings of the study reveal that the cost of cultivation of tomato under poly houses was higher by Rs. 206816.90/acre as com-pared to open field conditions. At the same time, the net returns under poly houses were higher by Rs. 51097.54/acre. Farmers realized 53.71 % higher yield of tomato under poly house as compared to open field conditions. The gross return, returns over variable cost and net return were also higher by 106.94 %, 160.70 % and 48.70 %, respectively in case of poly house as compared to open field conditions. The results of the study also revealed that the tomato cultivation under poly houses has significantly contributed to the yield

Does size matter? The benefits and challenges of voluntary sector partnerships in dementia service provision for South Asian communities in England

YesIn response to the need for improved access to dementia services for minority ethnic communities, the Alzheimer’s Society piloted, in 2014, the Information Programme for South Asian Families (IPSAF), an adapted version of its existing course for carers. It delivered this in partnership with local black and minority ethnic community and faith organisations, a new approach for the Alzheimer’s Society. In most cases, the partnerships formed were strong and effective, and have given rise to ongoing plans for joint working that bring benefits to both the local organisations and the Alzheimer’s Society. However, the current realities of UK voluntary and community sector dynamics raise questions of ownership and issues around how to establish genuine partnerships. In this article, we reflect on what the IPSAF experience indicates about the potential for equitable partnerships between small and large organisations, and draw out lessons for building effective, mutually beneficial relationships

An economic analysis of cucumber (Cucumis sativus L.) cultivation in eastern zone of Haryana (India) under polyhouse and open field condition

The study was conducted in north zone of Haryana (India) state to find out the economic analysis of cucumber cultivation under polyhouse and open field condition. The primary data was collected by personal interview of the selected respondents with the help of well-designed and pre tested schedule. Simple statistical tools like average and percentage were used to calculate the economics of the crop. In the present study, it was found that the cost of cultivation of cucumber per acre under polyhouse was Rs. 283684.40 while in case of open field condition it was Rs. 98003.39. In case of production and net returns, it was higher per acre in polyhouse; 245.47 quintal and Rs. 97138.68, respectively. Present study concluded that yield and income of farmers can be increased with help of polyhouse technology in case of cucumber cultivation

What do adolescents perceive to be key features of an effective dementia education and awareness initiative?

The development of dementia friendly communities is a current global and national priority for the UK. As a response to policy, there have been a number of dementia awareness initiatives disseminated with the aim of reducing the stigma associated with a diagnosis of dementia. The inclusion of adolescents in such initiatives in imperative in order to sustain dementia friendly communities. With this is mind, the aim of this study was to establish the dementia education needs of adolescents and effective dissemination strategies to convey key messages. A total of 42 adolescents aged 12 to 18 years participated in eight focus group discussions. Key themes to emerge from discussions included: the importance of dementia awareness, topics of interest within dementia, preferred methods of learning, the inclusion of the person living with dementia and the use of social media. The findings of the study will enable the development of appropriate dementia awareness initiatives for adolescents and thus facilitate the sustainability of dementia friendly communities