An Examination of Paper Manufacture Quality Control Methods and How They Effect Consumer Complaints

Information gathered by means of a consumer survey indicates that the majority of problems affecting roll runnability are caused by employee work habits and supervision, rather than machinery, during the manufacture of a roll of paper. A second survey, in the form of a three-part questionnaire, was sent to mills in the United States and Canada, producing newsprint, fine paper, groundwood printing and specialty papers. The survey obtained information about testing and supervision procedures plus the formal training of those responsible for quality control. The conclusion indicate that the lack of professional training may contribute to potential customer complaints

Ultrasonic locating devices for central venous cannulation: meta-analysis

OBJECTIVES: To assess the evidence for the clinical effectiveness of ultrasound guided central venous cannulation. DATA SOURCES: 15 electronic bibliographic databases, covering biomedical, science, social science, health economics, and grey literature. DESIGN: Systematic review and meta-analysis of randomised controlled trials. POPULATIONS: Patients scheduled for central venous access. INTERVENTION REVIEWED: Guidance using real time two dimensional ultrasonography or Doppler needles and probes compared with the anatomical landmark method of cannulation. DATA EXTRACTION: Risk of failed catheter placement (primary outcome), risk of complications from placement, risk of failure on first attempt at placement, number of attempts to successful catheterisation, and time (seconds) to successful catheterisation. DATA SYNTHESIS: 18 trials (1646 participants) were identified. Compared with the landmark method, real time two dimensional ultrasound guidance for cannulating the internal jugular vein in adults was associated with a significantly lower failure rate both overall (relative risk 0.14, 95% confidence interval 0.06 to 0.33) and on the first attempt (0.59, 0.39 to 0.88). Limited evidence favoured two dimensional ultrasound guidance for subclavian vein and femoral vein procedures in adults (0.14, 0.04 to 0.57 and 0.29, 0.07 to 1.21, respectively). Three studies in infants confirmed a higher success rate with two dimensional ultrasonography for internal jugular procedures (0.15, 0.03 to 0.64). Doppler guided cannulation of the internal jugular vein in adults was more successful than the landmark method (0.39, 0.17 to 0.92), but the landmark method was more successful for subclavian vein procedures (1.48, 1.03 to 2.14). No significant difference was found between these techniques for cannulation of the internal jugular vein in infants. An indirect comparison of relative risks suggested that two dimensional ultrasonography would be more successful than Doppler guidance for subclavian vein procedures in adults (0.09, 0.02 to 0.38). CONCLUSIONS: Evidence supports the use of two dimensional ultrasonography for central venous cannulation

Public Interest Immunity: Al Megrahi v HM Advocate

The Lockerbie case has already contributed significantly to the jurisprudence of the law of evidence. Al Megrahi v HM Advocate continues in that vein, shedding some light on how the law relating to public interest immunity now operates following devolution

Impaired neural discrimination of emotional speech prosody in children with autism spectrum disorder and language impairment

Autism spectrum disorders (ASD) are characterized by deficient social and communication skills, including difficulties in perceiving speech prosody. The present study addressed processing of emotional prosodic changes (sad, scornful and commanding) in natural word stimuli in typically developed school aged children and in children with ASD and language impairment. We found that the responses to a repetitive word were diminished in amplitude in the children with ASD, reflecting impaired speech encoding. Furthermore, the amplitude of the MMN/LDN component, reflecting cortical discrimination of sound changes, was diminished in the children with ASD for the scornful deviant. In addition, the amplitude of the P3a, reflecting involuntary orienting to attention-catching changes, was diminished in the children with ASD for the scornful deviant and tended to be smaller for the sad deviant. These results suggest that prosody processing in ASD is impaired at various levels of neural processing, including deficient pre-attentive discrimination and involuntary orientation to speech prosody. (C) 2016 Elsevier Ireland Ltd. All rights reserved.Peer reviewe

Understanding How Juveniles Become Human Traffickers

Modern-day slavery, also known as human trafficking, exists and grows worldwide, exploiting people for their physical and sexual labor (Banks & Kyckelhahn, 2011). Though media sources and legal changes have increased awareness about the issue of human trafficking, there is still a great void of research about the population of traffickers and perpetrators, especially a particularly concerning population: youth traffickers (Blank, Troshynski, 2007). Youth perpetrators have an easier time recruiting minors into human trafficking because they appear more trustworthy. However, little to no research is available to explain the histories and characteristics of this phenomenon regarding youth perpetrators. Therefore, we will seek to begin answering the following research question: What are the experiences of youth perpetrators? Researchers will use a qualitative, exploratory research design and a non-probable snowball sampling method to examine the experiences of current perpetrators who trafficked while they were minors. Using a semi-structured, in-depth interview, researchers will triangulate data from audio transcripts and copious field notes. The interviews with traffickers will be completed with phenomenological interviewing. The data will be analyzed using grounded theory methodology in which the researchers will work through multiple stages of coding with an outside coder to increase believability and trustworthiness. The researchers will also conduct data analysis with a limited number of traffickers to expand the study’s believability. We expect to find coding trends and theories related to the childhood experiences of this population and their life outcomes. The findings of this research will assist in working against the recruitment of additional minors to human trafficking. The goal of this research is to increase a general understanding of the experiences of youth traffickers and perpetrators, as well as encouraging others to engage in more quality research opportunities about trafficking as a whole

The Effect of Early vs. Normal Calf Weaning on Feedlot Performance and Herd Management: A Cross-Discipline Case Study

A study of early vs. normal weaning of calves concludes that early weaning improves feedlot production efficiency, reducing per day and per pound feedlot production costs. Early weaned steers finished higher thus feedlot profitability was not affected. Early weaning has a positive affect on cow health and pasture utilization rates.Livestock Production/Industries,

Survival and Spatial Ecology of the Snapping Turtle, Chelydra serpentina, on the Upper Mississippi River

We studied the survival and spatial ecology of adult Snapping Turtles (Chelydra serpentina) on Pool 8 of the Upper Mississippi River (UMR) during 1997-2001. We captured 597 Snapping Turtles 745 times (333 adult males; 238 adult females; and 26 juveniles) at two study sites; Goose Island, Wisconsin and Lawrence Lake, Minnesota. From this sample, we radio-marked 104 Snapping Turtles of legal harvest size 128 times. Annual survival ranged from 0.857 to 1.000 and averaged 0.944 with Goose Island and Lawrence Lake estimates pooled. Legal harvest was the most important cause of mortality and accounted for 57% of documented deaths. Annual home range size using the Poly-Buff (PB) method averaged 11.13 ha and ranged from 2.20 ha to 37.18 ha. Emergent and rooted-floating aquatic vegetation were used disproportionally more than their availability and 72% of all locations collected during the active period occurred within these habitat types. Overall, radio-marked Snapping Turtles selected hibernacula in the following habitat categories; marshes (38%), main/side channels (28%), backwater sloughs and small ponds (14%), spring areas (10%), small tributary streams (7%), and tertiary channels (3%). Developing conservative, consistent harvest regulations among the states that border the UMR should be a management priority

Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation

Background: Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1). It is associated with reduced life expectancy, cardiovascular problems, a variety of insidiously progressing detrimental symptoms and metabolic malfunction. Treatments include surgery, radiotherapy and pharmacotherapy. Pegvisomant (PEG) is a genetically engineered GH analogue licensed as a third or fourth line option when other treatments have failed to normalise IGF-1 levels. Methods: Evidence about effectiveness and cost-effectiveness of PEG was systematically reviewed. Data were extracted from published studies and used for a narrative synthesis of evidence. A decision analytical economic model was identified and modified to assess the cost-effectiveness of PEG. Results: One RCT and 17 non-randomised studies were reviewed for effectiveness. PEG substantially reduced and rapidly normalised IGF-1 levels in the majority of patients, approximately doubled GH levels, and improved some of the signs and symptoms of the disease. Tumour size was unaffected at least in the short term. PEG had a generally safe adverse event profile but a few patients were withdrawn from treatment because of raised liver enzymes. An economic model was identified and adapted to estimate the lower limit for the cost-effectiveness of PEG treatment versus standard care. Over a 20 year time horizon the incremental cost-effectiveness ratio was pound81,000/QALY and pound212,000/LYG. To reduce this to pound30K/QALY would require a reduction in drug cost by about one third. Conclusion: PEG is highly effective for improving patients' IGF-1 level. Signs and symptoms of disease improve but evidence is lacking about long term effects on improved signs and symptoms of disease, quality of life, patient compliance and safety. Economic evaluation indicated that if current standards (UK) for determining cost-effectiveness of therapies were to be applied to PEG it would be considered not to represent good value for money