890 research outputs found

    Biaxial prestressing of brittle materials

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    Strengthening of chemically consolidated zirconia with tungsten fibers, graphite fibers, sapphire whiskers, and silicon carbide whiskers is investigated. Addition of silicon carbide whiskers gives the highest increase in strength of zirconia at room and elevated temperatures. Prestressing with tungsten cables increases tensile strength and ductilit

    Актуализация принципов планирования деятельности предприятия

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    Рассматриваются вопросы развития некоторых принципов планирования показателей деятельности предприятий в контексте современной парадигмы менеджмента, дается характеристика принципов планирования и условий их применения

    Recombinant human erythropoietin in the treatment of chemotherapy-induced anemia and prevention of transfusion requirement associated with solid tumors: A randomized, controlled study

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    Background: Anemia is a common side effect of anticancer chemotherapy. Blood transfusion, previously the only available treatment for chemotherapy-induced anemia, may result insome clinical or subclinical adverse effects in the recipients. Recombinant human erythropoietin (rhEPO) provides a new treatment modality for chemotherapy-induced anemia. Patients and methods: To evaluate the effect of rhEPO onthe need for blood transfusions and on hemoglobin (Hb)concentrations, 227 patients with solid tumors and chemotherapy-induced anemia were enrolled in a randomized, controlled, clinical trial. Of 189 patients evaluable for efficacy, 101 received 5000 IU rhEPO daily s.c, while 88 patients received no treatment during the 12-week controlled phase of the study. Results: The results demonstrate a statistically significant reduction in the need for blood transfusions (28% vs. 42%, P = 0.028) and in the mean volume of packed red blood cells transfused (152 ml vs. 190 ml, p = 0.044) in patients treated with rhEPO compared to untreated controls. This effect was even more pronounced in patients receiving platinum-based chemotherapy (26% vs. 45%, % 0.038). During the controlled treatment phase, the median Hb values increased in the rhEPO patients while remaining unchanged in the control group. The response was seen in all tumor types. Conclusions: RhEPO administration at a dose of 5000 IU daily s.c. increases hemoglobin levels and reduces transfusionrequirements in chemotherapy-induced anemia, especially during platinum-based chemotherap

    ℓ-space spectroscopy of the Cosmic Microwave Background with the BOOMERanG experiment

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    The BOOMERanG experiment has recently produced detailed maps of the Cosmic Microwave Background, where sub-horizon structures are resolved with good signal to noise ratio. A power spectrum (spherical harmonics) analysis of the maps detects three peaks, at multipoles ℓ = (213_(-13)^(+10)),(541_(-32)^(+20))(845_(-25)^(+12)). In this paper we discuss the data analysis and the implications of these results for cosmology

    Regulation 13D and the Regulatory Process

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    Pursuant to its authority under the Securities Exchange Act of 1934, the Securities and Exchange Commission (SEC) has promulgated Schedule 13D, which imposes certain disclosure requirements on persons within ten days of the date that they acquire more than five percent of the beneficial ownership of a public company. As this article goes to press Congress is on the verge of reducing the threshold acquisition percentage perhaps to two percent and shortening the window from ten days to two or even one day. As such, it seems an appropriate time to evaluate the welfare effects of these disclosure requirements

    Privacy in crowdsourcing:a systematic review

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    The advent of crowdsourcing has brought with it multiple privacy challenges. For example, essential monitoring activities, while necessary and unavoidable, also potentially compromise contributor privacy. We conducted an extensive literature review of the research related to the privacy aspects of crowdsourcing. Our investigation revealed interesting gender differences and also differences in terms of individual perceptions. We conclude by suggesting a number of future research directions.</p

    Restrictions on Short Sales: An Analysis of the Uptick Rule and Its Role in View of the October 1987 Stack Market Crash

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    On October 29, 1929 the stock market crashed. Congress used the crash as an opportunity to introduce the pervasive regulation of securities markets that exists today. One of many practices for which Congress considered regulation appropriate was short sales. Representative Adolph Sabath of Illinois wanted to ban all short sales\u27 in order to eliminate what we term \u27short selling\u27 . . . the greatest evil that has been permitted or sanctioned by the Government that I know of. Fifty-eight years later, on October 19, 1987 the stock market crashed again. In response to the crash, Congress and other regulators once again have called for increased regulation of the securities markets. And as before, there have been calls for increased regulation of short sales, although now the calls for regulation of short sales extend to the derivative markets as well. For example, Congressman Edward Markey, Chairman of the House Telecommunications and Finance Committee, reportedly considered a plan to limit short sales in the futures market

    Proactive and politically skilled professionals: What is the relationship with affective occupational commitment?

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    The aim of this study is to extend research on employee affective commitment in three ways: (1) instead of organizational commitment the focus is on occupational commitment; (2) the role of proactive personality on affective occupational commitment is examined; and (3) occupational satisfaction is examined as a mediator and political skills as moderator in the relationship between proactive personality and affective occupational commitment. Two connected studies, one in a hospital located in the private sector and one in a university located in the public sector, are carried out in Pakistan, drawing on a total sample of over 400 employees. The results show that proactive personality is positively related to affective occupational commitment, and that occupational satisfaction partly mediates the relationship between proactive personality and affective occupational commitment. No effect is found for a moderator effect of political skills in the relationship between proactive personality and affective occupational commitment. Political skills however moderate the relationship between proactive personality and affective organizational commitment

    How do MNC R&amp;D laboratory roles affect employee international assignments?

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    Research and development (R&#38;D) employees are important human resources for multinational corporations (MNCs) as they are the driving force behind the advancement of innovative ideas and products. International assignments of these employees can be a unique way to upgrade their expertise; allowing them to effectively recombine their unique human resources to progress existing knowledge and advance new ones. This study aims to investigate the effect of the roles of R&#38;D laboratories in which these employees work on the international assignments they undertake. We categorise R&#38;D laboratory roles into those of the support laboratory, the locally integrated laboratory and the internationally interdependent laboratory. Based on the theory of resource recombinations, we hypothesise that R&#38;D employees in support laboratories are not likely to assume international assignments, whereas those in locally integrated and internationally interdependent laboratories are likely to assume international assignments. The empirical evidence, which draws from research conducted on 559 professionals in 66 MNC subsidiaries based in Greece, provides support to our hypotheses. The resource recombinations theory that extends the resource based view can effectively illuminate the international assignment field. Also, research may provide more emphasis on the close work context of R&#38;D scientists rather than analyse their demographic characteristics, the latter being the focus of scholarly practice hitherto

    Development of a system for biaxial prestressing brittle materials

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    Strengthening zirconia with discontinuous tungsten graphite, sapphire, and silicon carbide fiber
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