RICORS2040 : The need for collaborative research in chronic kidney disease

Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true

El reto del aprendizaje basado en proyectos para trabajar en competencias trasversales. Aplicación a asignaturas de Electrónica en la ETSID de la UPV

Congreso Universitario de Innovación Educativa En las Enseñanzas Técnicas, CUIEET (26º. 2018. Gijón

The Role of Scavenging in Disease Dynamics

Contents Introduction................ 161 The Use of Animal Remains and the Exposure of Scavengers to Disease........ 163 The Relevance of Scavenging for Pathogens to Spread and Persist.......... 166 Human Related Factors Resulting in Increased Risk for Disease Transmission Through Scavenging.............. 170 Management of Scavenging to Reduce Disease Risks.............. 173 Restoration of Large Predators.................. 174 Elimination of Hunting of Scavengers............ 174 Destruction of Big Game and Domestic Animal Carcasses........... 174 Restoration of the Effects of Overabundance............. 175 Excluding Mammalian and Avian Scavengers from Natural Carrions.......... 176 Excluding Mammalian and Avian Scavengers from Vulture Restaurants........... 176 Conclusions and Future Perspectives........... 178 References............... 17

Innovative Nondestructive Measurements of Water Activity and the Content of Salts in Low-Salt Hake Minces

Impedance spectroscopy (IS), low-field proton nuclear magnetic resonance (LF 1H NMR), chloride titration, ion chromatography, and an ion selective electrode were used to investigate the physicochemical parameters and measure sodium and potassium contents in low-salt brines and fish. Salt solutions (0–3 w/w, %) and model products of minced hake with added NaCl (0.5–3.0 w/w, %), or a mixture of NaCl and KCl (50/50 w/w, %), were analyzed. Good correlation was observed between the sodium content determined by using the ion selective electrode method and ion chromatography (R2 = 0.97). In both salt solutions and fish minces, the impedance spectroscopy measurements could detect the difference in salt contents in mince with salt contents down to 0.5%. The NMR transversal relaxation time T2 measurements clearly distinguished samples with 0, 0.5, and 1.0–3.0% salt, based on principal component analysis (PCA). Therefore, LF 1H NMR seems to be a suitable technique for studies of low-salt products.acceptedVersio