Experimental study on Gaussian-modulated coherent states quantum key distribution over standard telecom fiber

In this paper, we present a fully fiber-based one-way Quantum Key Distribution (QKD) system implementing the Gaussian-Modulated Coherent States (GMCS) protocol. The system employs a double Mach-Zehnder Interferometer (MZI) configuration in which the weak quantum signal and the strong Local Oscillator (LO) go through the same fiber between Alice and Bob, and are separated into two paths inside Bob's terminal. To suppress the LO leakage into the signal path, which is an important contribution to the excess noise, we implemented a novel scheme combining polarization and frequency multiplexing, achieving an extinction ratio of 70dB. To further minimize the system excess noise due to phase drift of the double MZI, we propose that, instead of employing phase feedback control, one simply let Alice remap her data by performing a rotation operation. We further present noise analysis both theoretically and experimentally. Our calculation shows that the combined polarization and frequency multiplexing scheme can achieve better stability in practice than the time-multiplexing scheme, because it allows one to use matched fiber lengths for the signal and the LO paths on both sides of the double MZI, greatly reducing the phase instability caused by unmatched fiber lengths. Our experimental noise analysis quantifies the three main contributions to the excess noise, which will be instructive to future studies of the GMCS QKD systems. Finally, we demonstrate, under the "realistic model" in which Eve cannot control the system within Bob's terminal, a secure key rate of 0.3bit/pulse over a 5km fiber link. This key rate is about two orders of magnitude higher than that of a practical BB84 QKD system.Comment: 21 pages, 9 figure

Experimental quantum tossing of a single coin

The cryptographic protocol of coin tossing consists of two parties, Alice and Bob, that do not trust each other, but want to generate a random bit. If the parties use a classical communication channel and have unlimited computational resources, one of them can always cheat perfectly. Here we analyze in detail how the performance of a quantum coin tossing experiment should be compared to classical protocols, taking into account the inevitable experimental imperfections. We then report an all-optical fiber experiment in which a single coin is tossed whose randomness is higher than achievable by any classical protocol and present some easily realisable cheating strategies by Alice and Bob.Comment: 13 page

Demonstration of the First Prototype of RUGBI, Design and Deployment of a Grid for Bioinformatics

présenté par N. Jacq, proceedings publiés par "Studies in health technology and informatics" seriesInternational audienceRUGBI is an industrial and academic project to design and deploy on top of existing technologies a computing grid offering a set of grid and bioinformatics services to analyse proteins. It aims to support life sciences SMEs for computing and storage, to deploy an interregional grid for bioinformatics and to create a biologists community in a grid environment. The proposed demonstration presents the first prototype of RUGBI architecture and bioinformatics services

Clinical features and outcome of bone and joint infections with streptococcal involvement: 5-year experience of interregional reference centres in the south of France

International audienceStreptococcal bone and joint infections are less common than staphylococcal cases. Few studies have reported the cases with well-identified Streptococcus species. Their clinical features and prognosis are not clearly known to date. Moreover, no treatment regimen has yet been clarified. We reviewed the streptococcal bone and joint infection cases managed in our centres from We described the epidemiology, clinical and microbiologic characteristics, treatment approach and outcome. Among the 93 cases, 83% of patients were men with a median age of 60 years, and 90% of patients had comorbidities or risk factors. Bacteraemia occurred in 14% of cases. Serious complications occurred in six patients, including severe sepsis (two cases) and infective endocarditis (two cases). Orthopaedic device infections were observed in 35% of cases, including 17 patients with internal osteosynthesis device infection, 14 with prosthetic joint infection and three with vertebral osteosynthesis device infection. The median time between orthopaedic device implantation and onset of infection was 447 days. Fourteen species of Streptococcus were identified, including 97 isolates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and three isolates using molecular identification. The five most represented species included S. agalactiae (37%), S. dysgalactiae (12%), S. anginosus (11%), S. constellatus (10%) and S. pneumoniae (9%). Streptococci isolates were susceptible to amoxicillin, with the exception of one S. mitis isolate. Remission 1 year after the end of treatment was recorded in 83%. One patient died of infection; eight patients had infections that failed to respond to treatment; and seven patients experienced relapse. Twenty patients (22%) had an unfavourable functional outcome, including 19 amputations and one arthrodesis. Five significant prognostic factors associated with an unfavourable clinical outcome were identified, including peripheral neuropathy (p 0.009), peripheral arterial disease (p 0.019), diabetes mellitus (p 0.031), location in the femur (p 0.0036), location in the foot (p 0.0475), osteitis without an orthopaedic device (p 0.041) and infection caused by S. dysgalactiae (p 0.020). The rate of poor outcomes remains high despite the low number of Streptococcus isolates resistant to antibiotics. Some prognostic factors, such as the presence of S. dysgalactiae, are associated with an unfavourable clinical outcome. Antibiotic regimens of streptococcal bone and joint infections are not standardized and need to be further investigated

Illusory movements prevent cortical disruption caused by immobilization

International audienceEnforced limb disuse strongly disrupts the cortical networks that are involved in sensorimotor activities. This disruption causes a cortical reorganization that may be functionally maladaptive. In this study, we used functional magnetic resonance imaging (fMRI) to investigate whether it is possible to prevent this reorganization by compensating for the lack of actual kinesthetic perception with illusory movements induced by ``neuromimetic'' proprio-tactile feedback that is artificially delivered during immobilization. Sixteen healthy volunteers were equipped for five days with full-hand ortheses that prevented them from performing finger and hand movements but allowed for kinesthetic and tactile sensations. Eight participants received a twice-daily proprio-tactile treatment consisting of the perception of kinesthetic sensations resembling those felt during actual movements generated by miniature vibrators set in the ortheses at the finger and wrist levels. Eight untreated participants received no stimulation. The effects of hand immobilization and treatment were assessed by fMRI during a calibrated voluntary hand movement task and hand tactile stimulation before cast placement and immediately after cast removal. We found that the sensorimotor network was preserved in subjects who underwent this treatment during hand immobilization, while the sensorimotor network of untreated subjects was significantly altered. These findings suggest that sensory feedback and associated movement perception may counteract disuse-induced cortical plastic changes through recruitment of a large part of the cortical network used for actual performed movement. The possibility of guiding cortical plasticity with proprioceptive augmented feedback is potentially relevant for rehabilitation efforts. (C) 2012 Elsevier Inc. All rights reserved

Experimental study of polarization properties of highly birefringent photonic crystal fibers

We analyze experimentally the polarization properties of highly nonlinear small-core photonic crystal fibers (PCFs) with no intentional birefringence. The properties of recently emerged polarization maintaining PANDA PCFs are also investigated. The wavelength and temperature dependence of phase and group delay of these fibers are examined in the telecommunications wavelength range. Compared to a standard PANDA fiber, the polarization characteristics and temperature dependence are found to be qualitatively different for both types of fiber

Grid infrastructures for computational neuroscience: The neuGRID example

Neuroscience is increasingly making use of statistical and mathematical tools to extract information from images of biological tissues. Computational neuroimaging tools require substantial computational resources and the increasing availability of large image datasets will further enhance this need. Many efforts have been directed towards creating brain image repositories including the recent US Alzheimer Disease Neuroimaging Initiative. Multisite-distributed computing infrastructures have been launched with the goal of fostering shared resources and facilitating data analysis in the study of neurodegenerative diseases. Currently, some Grid- and non-Grid-based projects are aiming to establish distributed e-infrastructures, interconnecting compatible imaging datasets and to supply neuroscientists with the most advanced information and communication technologies tools to study markers of Alzheimer's and other brain diseases, but they have so far failed to make a difference in the larger neuroscience community. NeuGRID is an Europeon comission-funded effort arising from the needs of the Alzheimer's disease imaging community, which will allow the collection and archiving of large amounts of imaging data coupled with Grid-based algorithms and sufficiently powered computational resources. The major benefit will be the faster discovery of new disease markers that will be valuable for earlier diagnosis and development of innovative drugs. The initial setup of neuGRID will feature three nodes equipped with supercomputer capabilities and resources of more than 300 processor cores, 300 GB of RAM memory and approximately 20 TB of physical space. The scope of this article is highlights the new perspectives and potential for the study of the neurodegenerative disorders using the emerging Grid technology. © 2009 Future Medicine Ltd