145 research outputs found
Comparative Myology and Evolution of Marsupials and Other Vertebrates, With Notes on Complexity, Bauplan, and "Scala Naturae"
Global entrainment of transcriptional systems to periodic inputs
This paper addresses the problem of giving conditions for transcriptional
systems to be globally entrained to external periodic inputs. By using
contraction theory, a powerful tool from dynamical systems theory, it is shown
that certain systems driven by external periodic signals have the property that
all solutions converge to a fixed limit cycle. General results are proved, and
the properties are verified in the specific case of some models of
transcriptional systems. The basic mathematical results needed from contraction
theory are proved in the paper, making it self-contained
Modern pollen rain and fungal spore assemblages from pasture woodlands around Lake Saint-Point (France)
Bundle of care taking into account time to improve long-term outcome after cardiac arrest
Antiarrhythmic drugs in out-of-hospital cardiac arrest: is there a place for potassium chloride?
Association between hyperoxemia and mortality in patients treated by eCPR after out-of-hospital cardiac arrest
Étude de la cinétique per-effort des paramètres des gaz du sang veineux au cours d'un ultra-trail
Variable selection methods were poorly reported but rarely misused in major medical journals: Literature review
International audienceObjective This work presents a review of the literature on reporting, practice and misuse of knowledge-based and data-driven variable selection methods, in five highly cited medical journals, considering recoding and interaction unlike previous reviews. Study Design and Setting Original observational studies with a predictive or explicative research question with multivariable analyses published in N. Engl. J. Med., Lancet, JAMA, Br. Med. J. and Ann. Intern. Med. between 2017 and 2019 were searched. Article screening was performed by a single reader, data extraction was performed by two readers and a third reader participated in case of disagreement. The use of data-driven variable selection methods in causal explicative questions was considered as misuse. Results 488 articles were included. The variable selection method was unclear in 234 (48%) articles, data-driven in 78 (16%) articles and knowledge-based in 176 (36%) articles. The most common data-driven methods were: Univariate selection (n = 22, 4.5%) and model comparisons or testing for interaction (n = 17, 3.5%). Data-driven methods were misused in 51 (10.5%) of articles. Conclusion Overall reporting of variable selection methods is insufficient. Data-driven methods seem to be used only in a minority of articles of the big five medical journals
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