Language as a social reality: The effects of the infantilization of women

The current study examined how people’s perceptions can be affected by various terms used to describe women. Participants from a Midwestern university read a script describing 26-year-old Erin either as a “woman,” a “girl,” or “person.” Participants then rated Erin on eighteen different traits (e.g., mature, forceful). They also completed an ambivalent sexism scale and answered three questions about their use and interpretations of the terms “girl” and “woman.” It was predicted that the participants in the “woman” condition would rate Erin as more mature, responsible, warm, understanding, and successful than the participants in the “girl” condition. Also, it was predicted that those in the “girl” condition would rate Erin as more feminine, gullible, and childlike. A research question asked how differing levels of ambivalent sexism might affect the ratings of Erin. Only 34% of participants were able to correctly recall how Erin was described in the scenario (i.e., girl, woman, person). There were few effects of gender or interactions, with no main effects of condition. Overall, higher levels of ambivalent sexism did significantly correlate with a few trait ratings of Erin. The qualitative results showed that over half of the participants reported using “girl” and less than a third reported using “woman” as their main term for adult females. Additionally, “girl” is often interpreted as more childlike, whereas “woman” is often interpreted as more adult-like. Although the manipulation did not seem to be effective, there was some evidence that there is some sort of effect of whether a woman is referred to as a “woman,” “girl,” or “person.

HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured. Animal models for the study of CRC-induced cachexia, in particular models containing LM, are sparse; therefore, we aimed to characterize two new models of CRC cachexia. Male NSG mice were injected subcutaneously (HCT116) or intrasplenically (mHCT116) with human HCT116 CRC tumor cells to disseminate LM, whereas experimental controls received saline (n=5-8/group). Tumor growth was accompanied by loss of skeletal muscle mass (HCT116: -20%; mHCT116: -31%; quadriceps muscle) and strength (HCT116: -20%; mHCT116: -27%), with worsened loss of skeletal muscle mass in mHCT116 compared with HCT116 (gastrocnemius: -19%; tibialis anterior: -22%; quadriceps: -21%). Molecular analyses revealed elevated protein ubiquitination in HCT116, whereas mHCT116 also displayed elevated Murf1 and atrogin-1 expression, along with reduced mitochondrial proteins PGC1α, OPA1, mitofusin 2 and cytochrome C. Further, elevated IL6 levels were found in the blood of mHCT116 hosts, which was associated with higher phosphorylation of STAT3 in skeletal muscle. To clarify whether STAT3 was a main player in muscle wasting in this model, HCT116 cells were co-cultured with C2C12 myotubes. Marked myotube atrophy (-53%) was observed, along with elevated phospho-STAT3 levels (+149%). Conversely, inhibition of STAT3 signaling by means of a JAK/STAT3 inhibitor was sufficient to rescue myotube atrophy induced by HCT116 cells (+55%). Overall, our results indicate that the formation of LM exacerbates cachectic phenotype and associated skeletal muscle molecular alterations in HCT116 tumor hosts

A way to estimate the heavy quark thermalization rate from the lattice

The thermalization rate of a heavy quark is related to its momentum diffusion coefficient. Starting from a Kubo relation and using the framework of the heavy quark effective theory, we argue that in the large-mass limit the momentum diffusion coefficient can be defined through a certain Euclidean correlation function, involving color-electric fields along a Polyakov loop. Furthermore, carrying out a perturbative computation, we demonstrate that the spectral function corresponding to this correlator is relatively flat at small frequencies. Therefore, unlike in the case of several other transport coefficients, for which the narrowness of the transport peak makes analytic continuation from Euclidean lattice data susceptible to severe systematic uncertainties, it appears that the determination of the heavy quark thermalization rate could be relatively well under control.Comment: 17 pages. v2: clarifications and references added, published versio

Breaking Ground: Planning and Building in Priority Growth Districts

The need to control sprawl, encourage Smart Growth, and create more livable neighborhoods that instill a sense of community through traditional neighborhood design, are topics in the forefront of national discussions about community planning and development. There is an innovative land use technique that can be used by communities to manage and define future growth in a way that creates more livable places, places that are environmentally, socially, and fiscally sound. Specifically, a community may designate mixed-use Priority Growth Districts, or PGDs, which direct development to selected locations and also specify a design that is attractive to the community’s current and future residents. This report provides the necessary tools and describes the steps that a community may take to designate Priority Growth Districts and reap their many benefits. The PGD concept discussed here is particularly suited for outlying suburban and exurban counties, where the rate of growth is significant but there is still a rural character that can be preserved. Growth in these areas may result from the actions of transportation agencies, which make outlying communities more accessible, from housing shortages in areas near job centers, or from the changing housing needs of current residents. The pressure to provide new homes can best be addressed through the identification of PGDs where roadways and other infrastructure either exist or can be accommodated. This report draws examples primarily from Dutchess and Orange counties in New York State, but the principles and techniques discussed here are applicable in various locations

Overwhelmed to Action: Digital Preservation Challenges at the Under-resourced Institution

Digital preservation advocates at small or mid-sized institutions struggle with the expectations of implementing a digital preservation program. Given that they operate with fewer resources than their larger colleagues, implementation can seem overwhelmingly difficult. With digital preservation a pressing issue, how do these libraries begin to tackle the challenge? Advocates at Milner Library have had the advantage of collaborating on the Institute of Museum and Library Services (IMLS) National Leadership Grant, Preserving (Digital) Objects With Restricted Resources (POWRR). This case study examines how they have applied the lessons they have learned to go from being overwhelmed to taking action. Along the way, they have encountered several misconceptions and challenges. This paper reviews the misconceptions and suggests approaches to the challenges of digital preservation. Some of the challenges include: minimal funds, change fatigue, lack of training, lack of engagement, and difficulty in framing the argument for administrators. Milner Library digital preservation advocates have approached the task by seeking collaborations, raising awareness, and starting small. It is possible to start the cultural change that is required to implement a digital preservation program, even with restricted resources

The INGRID project: Development of Solutions for Sustainable and Highly Interconnected Grids

One of the current main challenges in green-power storage and smart grids is the lack of effective solutions for accommodating the unbalance between renewable energy sources - offering intermittent electricity supply - and a variable electricity demand. Integrating intermittent renewable energy sources by safe and cost-effective energy storage systems is today achievable. Coupled with electrolizers, high-capacity solid-state storage of green-hydrogen is practicable to sustain integration, monitoring and control of large quantity of GWh from renewable generation. The 23.9 MLN Euros INGRID European large demonstrative project started in July 2012 combines magnesium-based material solid-state hydrogen storage systems with advanced ICT technologies to intelligently interconnect miscellaneous energy networks (i.e. electricity and gas) and safely delivering green-hydrogen to various existing or forthcoming markets. One solution INGRID project addresses is an off-grid utility to store renewable electricity captured from wind sources to refill full-battery electric cars

Colour-electric spectral function at next-to-leading order

The spectral function related to the correlator of two colour-electric fields along a Polyakov loop determines the momentum diffusion coefficient of a heavy quark near rest with respect to a heat bath. We compute this spectral function at next-to-leading order, O(alpha_s^2), in the weak-coupling expansion. The high-frequency part of our result (omega >> T), which is shown to be temperature-independent, is accurately determined thanks to asymptotic freedom; the low-frequency part of our result (omega << T), in which Hard Thermal Loop resummation is needed in order to cure infrared divergences, agrees with a previously determined expression. Our result may help to calibrate the overall normalization of a lattice-extracted spectral function in a perturbative frequency domain T << omega << 1/a, paving the way for a non-perturbative estimate of the momentum diffusion coefficient at omega -> 0. We also evaluate the colour-electric Euclidean correlator, which could be directly compared with lattice simulations. As an aside we determine the Euclidean correlator in the lattice strong-coupling expansion, showing that through a limiting procedure it can in principle be defined also in the confined phase of pure Yang-Mills theory, even if a practical measurement could be very noisy there.Comment: 38 page

On p_T-broadening of high energy partons associated with the LPM effect in a finite-volume QCD medium

We study the contributions from radiation to $p_{\perp}$-broadening of a high energy parton traversing a QCD medium with a finite length $L$. The interaction between the parton and the medium is described by decorrelated static multiple scattering. Amplitudes of medium-induced gluon emission and parton self-energy diagrams are evaluated in the soft gluon limit in the BDMPS formalism. We find both the double-logarithmic correction from incoherent scattering, which is parametrically the same as that in single scattering, and the logarithmic correction from the LPM effect. Therefore, we expect a parametrically large correction from radiation to the medium-induced $p_\perp$-broadening in perturbative QCD.Comment: 19 pages, focusing only on calculations about the medium-induced diagrams, origin for double-log reinterpreted, final version to appear in JHE

Spinor Helicity and Dual Conformal Symmetry in Ten Dimensions

The spinor helicity formalism in four dimensions has become a very useful tool both for understanding the structure of amplitudes and also for practical numerical computation of amplitudes. Recently, there has been some discussion of an extension of this formalism to higher dimensions. We describe a particular implementation of the spinor-helicity method in ten dimensions. Using this tool, we study the tree-level S-matrix of ten dimensional super Yang-Mills theory, and prove that the theory enjoys a dual conformal symmetry. Implications for four-dimensional computations are discussed.Comment: 24 pages, 1 figure