1,551 research outputs found
Una fiesta y varias fronteras: los Quintos de Barrancos (Portugal) y Noblejas (España)
En este artículo intentamos ensayar una perspectiva comparativa sobre la fiesta de los quintos en dos municipios distintos, uno en España y otro en Portugal. Para ello analizamos en primer lugar las formas en que se desarrolla la fiesta en ambos casos, señalando las coincidencias y diferencias que existen en la propia celebración. A partir de aquí se desarrolla el análisis comparativo, para el que se introduce una doble perspectiva: el pueblo y la villa como escenarios de la convivencia, y la fiesta como frontera en un sentido espacial y también temporal. Por último, se exponen algunas conclusiones sobre lo que se revela en la comparación
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival
There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5.5 (E5.5) to E7.5 epiblast and E7.5-E8.5 neuroectoderm in vivo. Definitive NSCs (LIF independent but FGF2 dependent) first appear in the E8.5 neural plate and persist throughout life. Primitive NSCs give rise to definitive NSCs. Loss and gain of functions were used to study the role of vascular endothelial growth factor (VEGF)-A and its receptor, Flk1, in NSCs. The numbers of Flk1 knock-out mice embryo-derived and ES cell-derived primitive NSCs were increased because of the enhanced survival of primitive NSCs. In contrast, neural precursor-specific, Flk1 conditional knock-out mice-derived, definitive NSCs numbers were decreased because of the enhanced cell death of definitive NSCs. These effects were not observed in cells lacking Flt1, another VEGF receptor. In addition, the cell death stimulated by VEGF-A of primitive NSC and the cell survival stimulated by VEGF-A of definitive NSC were blocked by Flk1/Fc-soluble receptors and VEGF-A function-blocking antibodies. These VEGF-A phenotypes also were blocked by inhibition of the downstream effector nuclear factor kappa B (NF-kappa B). Thus, both the cell death of primitive NSC and the cell survival of definitive NSC induced by VEGF-A stimulation are mediated by bifunctional NF-kappa B effects. In conclusion, VEGF-A function through Flk1 mediates survival (and not proliferative or fate change) effects on NSCs, specifically
Aplikasi Enkripsi SMS Dengan Modifikasi Vigenere Cipher Pada Ponsel Android
Communicating is one of the earth's human nature as a means of communicating to understand each other. As for how communication has developed very rapidly from era to era. One way is through writing or message. Messages a delivery of information that can be read and have meaning.In recent years, rapid development occurs on mobile phone technology (cell phones). One of them is a smart phone that has a full feature with complex operating system like a computer. Various operating system for mobile phones were introduced, such as Android. Although equipped with premium features and the operating system, for the security of the delivery of messages through SMS facility, is still considered inadequate. By encrypting the content of messages to be sent, then the level of information security of the message can be improved. Of the various techniques of encryption, encryption method Vigenere cipher Caesar cipher with modifications and Eulerian numbers chosen as the method with a light workload. Access to the message of the application must be secured with the password, so the message will be safe from unauthorized parties
Penggunaan Principal Component Analysis dan Euclidean Distance untuk Identifikasi Citra Tanda Tangan
Teknologi computer vision untuk identifikasi identitas spesifik seseorang telah banyak berkembang, baik identifikasi melalui sidik jari, retina, suara, bahkan tanda tangan. Tanda tangan merupakan identitas autentifikasi yang umum digunakan. Dengan perkembangan teknologi digital, diperlukan metode autentifikasi tanda tangan untuk memastikan keamanan, keaslian, dan kesesuaian tanda tangan. Penelitian ini bertujuan menggunakan metode Principal Component Analysis (PCA) dan Euclidean Distance untuk mengidentifikasi tanda tangan dengan perlakuan yang berbeda. Pengujian menunjukkan tingkat akurasi terbaik pada nilai threshold sebesar 50 – 219 dengan nilai akurasi 95%. Penggunaan dimensi berbeda antara citra training dan citra testing menghasilkan akurasi 60%. Pengujian dengan tinta warna berbeda menunjukan tingkat akurasi mencapai 100%. Dengan demikian, metode PCA dan Euclidean Distance dapat digunakan untuk mengidentifikasi tanda tangan
Experience using high-dose glucose-insulin-potassium (GIK) in critically ill patients
Purpose
To audit the use of GIK in terms of safety, haemodynamic effects, and impact on catecholamine dosage.
Materials and methods
A retrospective, descriptive, evaluative audit of GIK use within the adult ICU of a London teaching hospital was conducted. Rescue therapy of GIK (up to 1.0 Units insulin/kg/h) was administered to improve cardiac function. Outcomes were ICU survival, change in cardiac index (CI) and blood lactate levels, events of hypoglycaemia, hyperglycaemia, hypokalaemia and hyperkalaemia, and discontinuation time of catecholamine inotropes.
Results
Of 85 patients treated with GIK, 13 (15.3%) survived their ICU stay and 9 (10.5%) were discharged home. In patients surviving until 72 h, a trend of improved CI and lactate levels was seen, often with reductions in catecholamine dosing. Inotropes were discontinued in 35 (54%) patients. Severe hypoglycaemia ( 20 mmol/l), hypokalaemia ( 7 mmol/l) during GIK affected 1, 6, 8 and 1 patients, respectively. These abnormalities were quickly identified. No measurable harm was noted.
Conclusions
High-dose GIK can be safely used in critically ill patients, though blood glucose and potassium levels must be monitored frequently. GIK was associated with improved CI and blood lactate levels. Impact on survival requires prospective evaluation
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