MicroRNAs in B cell development and malignancy

MicroRNAs are small RNA molecules that regulate gene expression and play critical roles in B cell development and malignancy. miRNA expression is important globally, as B cell specific knockouts of Dicer show profound defects in B cell development; and is also critical at the level of specific miRNAs. In this review, we discuss miRNAs that are involved in normal B cell development in the bone marrow and during B cell activation and terminal differentiation in the periphery. Next, we turn to miRNAs that are dysregulated during diseases of B cells, including malignant diseases and autoimmunity. Further study of miRNAs and their targets will lead to a better understanding of B cell development, and should also lead to the development of novel therapeutic strategies against B cell diseases

Frequency Coded Chipless RFID Tag using Spurline Resonators

A novel compact chipless RFID tag using spurline resonators is discussed in this paper. The detection of the tag's ID is using the spectral signature of a spurline resonator circuit. The tag has a data capacity of 8-bits in the range 2.38 to 4.04 GHz. The tag consists of a spurline multiresonating circuit and two cross polarised antennas. The prototype of the tag is fabricated on a substrate C-MET/LK4.3 of dielectric constant 4.3 and loss tangent 0.0018. The measured results show that group delay response can also be used to decode the tag’s identity

Evaluation of mechanical and corrosive properties of aluminium AA7075 metal matrix composites

Composites are most successful materials used for recent works in the industries. Metal composites possess significantly improved properties including high tensile strength , toughness, hardness, low density and good wear resistance compared to alloys or any other metals .By increasing the content of Zirconium and Chromium in AA 7075 metal matrix composites corrosion resistance is increased.  Modified stir casting method is used for the even distribution of Zirconium and Chromium in AA7075 metal matrix composites. Ultimate tensile strength of AA7075 metal matrix composite improved by increasing the content of Zirconium and compared with unreinforced alloy of aluminum. Hardness and tensile strength of AA7075 composites is increased where ductility is decreased .Hence composites AA7075 metal matrix to enhance the mechanical and physical properties for widely used in the automobile and spacecraft applications to improve fuel efficiency. Aluminum metal matrix composites are being used in place of cast iron and steel due to their light weight and high strength

Data Storage, Security And Techniques In Cloud Computing

Cloud computing is the computing technology which provides resources like software, hardware, services over the internet. Cloud computing provides computation, software, data access, and storage services that do not require end- user knowledge of the physical location and configuration of the system that delivers the services. Cloud computing enables the user and organizations to store their data remotely and enjoy good quality applications on the demand without having any burden associated with local hardware resources and software managements but it possesses a new security risk towards correctness of data stored at cloud. The data storage in the cloud has been a promising issue in these days. This is due to the fact that the users are storing their valuable data and information in the cloud. The users should trust the cloud service providers to provide security for their data. Cloud storage services avoid the cost storage services avoids the cost expensive on software, personnel maintains and provides better performance less storage cost and scalability, cloud services through internet which increase their exposure to storage security vulnerabilities however security is one of the major drawbacks that preventing large organizations to enter into cloud computing environment. This work surveyed on several storage techniques and this advantage and its drawbacks

A hybrid multiple attribute decision making method for solving problems of industrial environment

The selection of appropriate alternative in the industrial environment is an important but, at the same time, a complex and difficult problem because of the availability of a wide range of alternatives and similarity among them. Therefore, there is a need for simple, systematic, and logical methods or mathematical tools to guide decision makers in considering a number of selection attributes and their interrelations. In this paper, a hybrid decision making method of graph theory and matrix approach (GTMA) and analytical hierarchy process (AHP) is proposed. Three examples are presented to illustrate the potential of the proposed GTMA-AHP method and the results are compared with the results obtained using other decision making methods