Hubungan Antara Iklim Organisasi Dengan Keterikatan Kerja Pada Karyawan PT Angkasa Pura I (Persero) Kantor Cabang Semarang

Organisasi dengan iklim organisasi yang positif dapat meningkatkan motivasi, keterlibatan dan produktivitas karyawan, serta kepuasan kerja yang pada akhirnya dapat meningkatkan keterikatan kerja dalam diri karyawan. Penelitian ini bertujuan untuk mengetahui hubungan antara iklim organisasi dan keterikatan kerja pada karyawan PT Angkasa Pura I (Persero) Kantor Cabang Semarang. Populasi dalam penelitian ini berjumlah 109 orang karyawan tetap PT Angkasa Pura I (Persero) Kantor Cabang Semarang, serta sampel penelitian berjumlah 65 karyawan. Alat ukur yang digunakan adalah Skala Keterikatan Kerja (29 aitem, α = 0,921) dan Skala Iklim Organisasi (31 aitem, α = 0,915). Analisis regresi sederhana menunjukkan adanya hubungan positif yang signifikan antara iklim organisasi dan keterikatan kerja (r = 0,786; p < 0,001), yang berarti bahwa semakin positif iklim organisasi maka semakin tinggi keterikatan kerja karyawan, dan sebaliknya, semakin negatif iklim organisasi maka semakin rendah keterikatan kerja karyawan. Iklim organisasi memberikan sumbangan efektif sebesar 61,8% pada keterikatan kerja. Kondisi tersebut menunjukkan bahwa tingkat konsistensi variabel keterikatan kerja sebesar 61,8% dapat diprediksi oleh iklim organisasi, sisanya 38,2% ditentukan oleh faktor lain yang tidak diukur dalam penelitian ini

Pengaruh Level Protein Dan Asam Asetat Dalam Ransum Terhadap Tingkat Keasaman (Ph) Usus Halus, Laju Digesta Dan Bobot Badan Akhirayam Broiler (the Effect of Levels Protein and Acetic Acid on Feed Formula to Potensial Hydrogen (Ph) Intestine Small, Digest

This research aims to determine the effect of levels protein and acetic acid on feed formula to pH small intestine, digest rate and final body weight of broiler. The materials used in the research were 180 unsex broiler chickens Lohman strain MB 202 with an average weight 45,6 ± 4,8 g. The ration used consisting of broken maize, rice bran, soybean meal, Poutry Meat Meal (PMM), fish meal and premix. The experimental design used was a completely randomized design (CRD) factorial 2x3 with 3 replications. The first factor, the protein level in ration, is CP 21% (T1) and 20% (T2), the second factor is the addition of acetic acid on level 0% (V0), 0,75% (V1), 1,5% (V2). Parameters were observed include pH small intestine, digest rate and final body weight. Research used variance analised.The results showed that the protein level of the ration with the addition of acetic acid in the diet there is no significant interaction (p> 0.05) on the pH small intestine, digesta rate and final body weight. Conclusion The study is a combination of levels protein 21% and 20% with the addition of acetic acid 0%, 0.75% and 1.5% in the diet has not been able to change the pH small intestine, digesta rate and final body weight

Anti-predator behaviour of the red-legged partridge Alectoris rufa (Galliformes: Phasianidae) to simulated terrestrial and aerial predators

This study is intended to investigate the differences in anti-predator behavioural and acoustic response to terrestrial and aerial predators as well as the behavioural differences between sexes in the red-legged partridge. To this aim we observed the response of 114 partridge (57 males and 57 females) to dummy terrestrial and aerial predators, a raptor and a fox. We divided behavioural responses to predators into four mutually exclusive categories: vigilance, freezing, escape and non-anti-predator behaviours. We also recorded and analysed the vocalizations emitted during tests. The animals reacted differently to aerial and terrestrial stimuli. The reactions elicited by the terrestrial predator were ranked as follows: vigilance, escape, non-anti-predator behaviours, and freezing. Those elicited by the aerial predator were ranked as follows: vigilance, freezing, escape and non-anti-predator behaviours. Vigilance and escape were elicited more frequently by the terrestrial predator than by the aerial predator (vigilance: p 0.001; escape: p 0.001). Freezing was the most frequent behaviour following the appearance of the aerial predator (p 0.001). In fact, freezing may represent an effective strategy in an open space, combining camouflage from and detection by the predator. On the other hand, vigilance is an effective behaviour to detect and avoid a terrestrial predator hunting by ambush. We did not find clear-cut differences between sexes. The analysis of vocalizations revealed that the fox and the raptor elicited significantly different calls (p = 0.003); the fox evoked significantly more vocalizations than the raptor (p 0.001), differing in addition in frequency parameters. Thus partridges not only discriminate between aerial and terrestrial predators and behave consequently, but are also able to tune alarm calls in relation to the context of predation

TF-IDF vs word embeddings for morbidity identification in clinical notes: An initial study

Today, we are seeing an ever-increasing number of clinical notes that contain clinical results, images, and textual descriptions of patient's health state. All these data can be analyzed and employed to cater novel services that can help people and domain experts with their common healthcare tasks. However, many technologies such as Deep Learning and tools like Word Embeddings have started to be investigated only recently, and many challenges remain open when it comes to healthcare domain applications. To address these challenges, we propose the use of Deep Learning and Word Embeddings for identifying sixteen morbidity types within textual descriptions of clinical records. For this purpose, we have used a Deep Learning model based on Bidirectional Long-Short Term Memory (LSTM) layers which can exploit state-of-the-art vector representations of data such as Word Embeddings. We have employed pre-trained Word Embeddings namely GloVe and Word2Vec, and our own Word Embeddings trained on the target domain. Furthermore, we have compared the performances of the deep learning approaches against the traditional tf-idf using Support Vector Machine and Multilayer perceptron (our baselines). From the obtained results it seems that the latter outperform the combination of Deep Learning approaches using any word embeddings. Our preliminary results indicate that there are specific features that make the dataset biased in favour of traditional machine learning approaches

New diagnostic possibilities in systemic neonatal infections: metabolomics

Systemic neonatal infection is a serious complication in preterm and term infants and is defined as a complex clinical syndrome caused by bacteria, fungi and virus. Sepsis remains among the leading causes of death in both developed and underdeveloped countries above all in the neonatal period. Earlier diagnosis may offer the ability to initiate treatment to prevent adverse outcomes. There have been many studies on various diagnostic haematological markers like acute phase reactants, C-reactive protein, procalcitonin, interleukins and presepsin. However, there is still no single test that satisfies the criteria as being the ideal marker for the early diagnosis of neonatal sepsis. In this regard, metabolomic analysis seems to be a promising method for determining metabolic variations correlated with systemic neonatal infection

Atherosclerosis, dyslipidemia, and inflammation: the significant role of polyunsaturated fatty acids

Phospholipids play an essential role in cell membrane structure and function. The length and number of double bonds of fatty acids in membrane phospholipids are main determinants of fluidity, transport systems, activity of membrane-bound enzymes, and susceptibility to lipid peroxidation. The fatty acid profile of serum lipids, especially the phospholipids, reflects the fatty acid composition of cell membranes. Moreover, long-chain n-3 polyunsatured fatty acids decrease very-low-density lipoprotein assembly and secretion reducing triacylglycerol production. N-6 and n-3 polyunsatured fatty acids are the precursors of signalling molecules, termed “eicosanoids,” which play an important role in the regulation of inflammation. Eicosanoids derived from n-6 polyunsatured fatty acids have proinflammatory actions, while eicosanoids derived from n-3 polyunsatured fatty acids have antiinflammatory ones. Previous studies showed that inflammation contributes to both the onset and progression of atherosclerosis: actually, atherosclerosis is predominantly a chronic low-grade inflammatory disease of the vessel wall. Several studies suggested the relationship between long-chain n-3 polyunsaturated fatty acids and inflammation, showing that fatty acids may decrease endothelial activation and affect eicosanoid metabolis

A Randomized, Placebo-Controlled, Double-Blind Trial of the Effect of Combined Therapy With Deferoxamine and Deferiprone on Myocardial Iron in Thalassemia Major Using Cardiovascular Magnetic Resonance

Background— Cardiac complications secondary to iron overload are the leading cause of death in β-thalassemia major. Approximately two thirds of patients maintained on the parenteral iron chelator deferoxamine have myocardial iron loading. The oral iron chelator deferiprone has been demonstrated to remove myocardial iron, and it has been proposed that in combination with deferoxamine it may have additional effect. Methods and Results— Myocardial iron loading was assessed with the use of myocardial T2* cardiovascular magnetic resonance in 167 patients with thalassemia major receiving standard maintenance chelation monotherapy with subcutaneous deferoxamine. Of these patients, 65 with mild to moderate myocardial iron loading (T2* 8 to 20 ms) entered the trial with continuation of subcutaneous deferoxamine and were randomized to receive additional oral placebo (deferoxamine group) or oral deferiprone 75 mg/kg per day (combined group). The primary end point was the change in myocardial T2* over 12 months. Secondary end points of endothelial function (flow-mediated dilatation of the brachial artery) and cardiac function were also measured with cardiovascular magnetic resonance. There were significant improvements in the combined treatment group compared with the deferoxamine group in myocardial T2* (ratio of change in geometric means 1.50 versus 1.24; P =0.02), absolute left ventricular ejection fraction (2.6% versus 0.6%; P =0.05), and absolute endothelial function (8.8% versus 3.3%; P =0.02). There was also a significantly greater improvement in serum ferritin in the combined group (−976 versus −233 μg/L; P <0.001). Conclusions— In comparison to the standard chelation monotherapy of deferoxamine, combination treatment with additional deferiprone reduced myocardial iron and improved the ejection fraction and endothelial function in thalassemia major patients with mild to moderate cardiac iron loading

MODEL MATEMATIKA KECANDUAN TERHADAP AIBON

penelitian ini membahas model matematika kecanduan terhadap konsumsi aibon. Dalam skema asumsi kasus kecanduan aibon mendekati kondisi riil. Kecanduan akibat senyawa Lysergic Acid Diethyilamide (LSD) memperlihatkan prilaku dalam system endemik. Oleh karenanya, untuk pemodelan matematika dapat di peroleh. Model disusun dalam pembagian klaster populasi tertutup. Populasi potensial, populasi pecandu aktif dan populasi pecandu yang berhenti. Pada sistem model titik equilibrium yang memungkinkan muncul ada tiga, yaitu &nbsp;dan . Sementara dari ketiga equilibrium tersebut yang asimtotik stabil adalah . Diperoleh juga nilai Reproduction number &nbsp;yaitu sebesar . Dari nilai &nbsp;yang diperoleh inilah dapat dinyatakan bahwa untuk populasi pecandu aktif dapat direduksi. Model matematika kecanduan terhadap aibon ini disajikan untuk mengetahui kelakuan solusi model dan laju perubahan pecandu aktif jika diakukan pengontrolan dan jika tidak dilakukan pengontrolan

Alcohol-related behaviour in freshmen university students in Sardinia, Italy

This study aims to provide a picture of University of Cagliari students’ alcohol-related behaviour and to explore factors associated with it. Data were collected by administering a questionnaire to 992 freshmen university students from different programs consisting of twelve closed questions, including three questions from the Alcohol Use Disorders Identification Test for Consumption (AUDIT-C short form). Three subgroups of alcohol-related behaviour were distinguished (risky drinkers, social drinkers and abstainers). In order to explore factors associated with patterns of alcohol consumption, a multivariate logistic regression was performed. The prevalence of risky drinkers was 35%. A binge-drinking behaviour at least once in the last twelve months was declared by 65% (more widespread in men and in students living away from their parents). Risky consumption is significantly associated with age of onset of alcohol use, living away from parents’ home, drinking outside meals and attending health courses. Regarding the levels of daily alcohol consumption perceived as a health risk, 66% of men and 88% of women indicate values higher than those recommended. The results underline the need for tailored prevention measures. University could be a promising setting to implement actions according to a health promotion perspective, to empower students to control their alcohol consumption

Urinary metabolomics (GC-MS) reveals that low and high birth weight infants share elevated inositol concentrations at birth

Objective: Metabolomics is a new ‘‘omics’’ platform aimed at high-throughput identification, quantification and characterization of small molecule metabolites. The metabolomics approach has been successfully applied to the classification different physiological states and identification of perturbed biochemical pathways. The purpose of the current investigation is the application of metabolomics to explore biological mechanisms which may lead to the onset of metabolic syndrome in adulthood. Methods: We evaluated differences in metabolites in the urine collected within 12 hours from 23 infants with IUGR (IntraUterine Growth Restriction), or LGA (Large for Gestational Age), compared to control infants (10 patients defined AGA: Appropriate for Gestational Age). Urinary metabolites were quantified by GC-MS and used to highlight similarities between the two metabolic diseases and identify metabolic markers for their predisposition. Quantified metabolites were analyzed using a multivariate statistics coupled with receiver operator characteristic curve (ROC) analysis of identified biomarkers. Results: Urinary myo-inositol was the most important discriminant between LGA + IUGR and control infants, and displayed an area under the ROC curve¼1. Conclusion: We postulate that the increase in plasma and consequently urinary inositol may constitute a marker of altered glucose metabolism during fetal development in both IUGR and LGA newborns