311 research outputs found
Toward the use of similarity theory in two-phase choked flows
Comparison of two phase choked flows in normalized coordinates were made between pure components and available data using a reference fluid to compute the thermophysical properties. The results are favorable. Solution of the governing equations for two LNG mixtures show some possible similarities between the normalized choked flows of the two mixtures, but the departures from the pure component loci are significant
Tumour necrosis factor-α up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-κB
BACKGROUND: A series of controlled changes including proliferation, secretion and menstrual shedding occur in the human endometrium during every normal menstrual cycle. Macrophage migration inhibitory factor (MIF), a multifunctional cytokine with numerous proinflammatory, immunomodulatory and angiogenic properties, appears to be expressed in the human endometrium and to follow a regulated cycle phase-dependent expression, but the mechanisms underlying endometrial MIF expression remain to be fully elucidated. METHODS AND RESULTS: Results from enzyme-linked immunosorbent assay (ELISA) demonstrated a significant dose- and time-dependent increase in MIF secretion by human endometrial cells in response to tumour necrosis factor-alpha (TNF-α) (0.1-100 ng/ml). This increase was also observed at the mRNA level as shown by reverse transcription (RT)-PCR. Curcumin (10−8 mol/l), a known nuclear factor (NF)-κB inhibitor, inhibited the TNF-α-induced pIκB phosphorylation as shown by western blotting, NF-κB translocation into the nucleus as shown by electrophoretic mobility shift assay, and MIF synthesis and secretion as measured by ELISA and RT-PCR. The expression of a dominant-negative NF-κB inhibitor (IκB) significantly decreased the TNF-α-induced MIF promoter activity as analysed by transient cell transfection. CONCLUSIONS: These results indicate clearly that TNF-α up-regulates the expression of MIF in endometrial stromal cells. This took place possibly through NF-κB activation, and may play an important role in the physiology of the human endometriu
Master crossover functions for the one-component fluid "subclass"
Introducing three well-defined dimensionless numbers, we establish the link
between the scale dilatation method able to estimate master (i.e. unique)
singular behaviors of the one-component fluid "subclass" and the universal
crossover functions recently estimated [Garrabos and Bervillier, Phys. Rev. E
74, 021113 (2006)] from the bounded results of the massive renormalization
scheme applied to the..
Critical Viscosity Exponent for Fluids: What Happend to the Higher Loops
We arrange the loopwise perturbation theory for the critical viscosity
exponent , which happens to be very small, as a power series in
itself and argue that the effect of loops beyond two is negligible.
We claim that the critical viscosity exponent should be very closely
approximated by .Comment: 9 pages and 3 figure
Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB.
Existence of a critical point in the phase diagram of the ideal relativistic neutral Bose gas
We explore the phase transitions of the ideal relativistic neutral Bose gas
confined in a cubic box, without assuming the thermodynamic limit nor
continuous approximation. While the corresponding non-relativistic canonical
partition function is essentially a one-variable function depending on a
particular combination of temperature and volume, the relativistic canonical
partition function is genuinely a two-variable function of them. Based on an
exact expression of the canonical partition function, we performed numerical
computations for up to hundred thousand particles. We report that if the number
of particles is equal to or greater than a critical value, which amounts to
7616, the ideal relativistic neutral Bose gas features a spinodal curve with a
critical point. This enables us to depict the phase diagram of the ideal Bose
gas. The consequent phase transition is first-order below the critical pressure
or second-order at the critical pressure. The exponents corresponding to the
singularities are 1/2 and 2/3 respectively. We also verify the recently
observed `Widom line' in the supercritical region.Comment: 1+25 pages, 6 B/W figures: Comment on the Widom line added. Minor
improvement. Version to appear in `New Journal of Physics
Thermodynamic characteristics of the classical n-vector magnetic model in three dimensions
The method of calculating the free energy and thermodynamic characteristics
of the classical n-vector three-dimensional (3D) magnetic model at the
microscopic level without any adjustable parameters is proposed. Mathematical
description is perfomed using the collective variables (CV) method in the
framework of the model approximation. The exponentially decreasing
function of the distance between the particles situated at the N sites of a
simple cubic lattice is used as the interaction potential. Explicit and
rigorous analytical expressions for entropy,internal energy, specific heat near
the phase transition point as functions of the temperature are obtained. The
dependence of the amplitudes of the thermodynamic characteristics of the system
for and on the microscopic parameters of the interaction
potential are studied for the cases and . The obtained
results provide the basis for accurate analysis of the critical behaviour in
three dimensions including the nonuniversal characteristics of the system.Comment: 25 pages, 5 figure
Free Energy Minimizers for a Two--Species Model with Segregation and Liquid-Vapor Transition
We study the coexistence of phases in a two--species model whose free energy
is given by the scaling limit of a system with long range interactions (Kac
potentials) which are attractive between particles of the same species and
repulsive between different species.Comment: 32 pages, 1 fig, plain tex, typeset twic
Communication: Analytic continuation of the virial series through the critical point using parametric approximants
The mathematical structure imposed by the thermodynamic critical point motivates an approximant that synthesizes two theoretically sound equations of state: the parametric and the virial. The former is constructed to describe the critical region, incorporating all scaling laws; the latter is an expansion about zero density, developed from molecular considerations. The approximant is shown to yield an equation of state capable of accurately describing properties over a large portion of the thermodynamic parameter space, far greater than that covered by each treatment alone
- …