SEAGRID: A New Dynamic Modelling Tool for Power System Analysis of Ocean Energy Devices

International audienceAs the ocean energy industry approaches commercial readiness, there will be a greater focus on integration of ocean energy devices (OEDs) into the electrical power system network. Device developers will be required to provide dynamic models of their device for grid connection, and ensure their device operates within the limits laid out in the grid code. Project developers will need to assess the impact of different wavefarm configurations, ratings for the electrical equipment, power losses, and performance during a fault. Grid operators will require dynamic models to investigate the impact an OED will have on the grid and also for future grid planning studies. The SEAGRID dynamic modelling tool attempts to address each of these issues using its generic modelling approach. The SEAGRID model is capable of producing a scalable time domain power system dynamic model using empirical test data and component specifications, bypassing the need for a full hydrodynamic study of the device

ZFIRE: The Evolution of the Stellar Mass Tully-Fisher Relation to Redshift 2.0 < Z < 2.5 with MOSFIRE

Using observations made with MOSFIRE on Keck I as part of the ZFIRE survey, we present the stellar mass Tully-Fisher relation at 2.0 < z < 2.5. The sample was drawn from a stellar mass limited, Ks-band selected catalog from ZFOURGE over the CANDELS area in the COSMOS field. We model the shear of the Halpha emission line to derive rotational velocities at 2.2X the scale radius of an exponential disk (V2.2). We correct for the blurring effect of a two-dimensional PSF and the fact that the MOSFIRE PSF is better approximated by a Moffat than a Gaussian, which is more typically assumed for natural seeing. We find for the Tully-Fisher relation at 2.0 < z < 2.5 that logV2.2 =(2.18 +/- 0.051)+(0.193 +/- 0.108)(logM/Msun - 10) and infer an evolution of the zeropoint of Delta M/Msun = -0.25 +/- 0.16 dex or Delta M/Msun = -0.39 +/- 0.21 dex compared to z = 0 when adopting a fixed slope of 0.29 or 1/4.5, respectively. We also derive the alternative kinematic estimator S0.5, with a best-fit relation logS0.5 =(2.06 +/- 0.032)+(0.211 +/- 0.086)(logM/Msun - 10), and infer an evolution of Delta M/Msun= -0.45 +/- 0.13 dex compared to z < 1.2 if we adopt a fixed slope. We investigate and review various systematics, ranging from PSF effects, projection effects, systematics related to stellar mass derivation, selection biases and slope. We find that discrepancies between the various literature values are reduced when taking these into account. Our observations correspond well with the gradual evolution predicted by semi-analytic models.Comment: 21 pages, 14 figures, 1 appendix. Accepted for publication by Apj, February 28, 201

Generic Dynamic Modelling for Grid Integration of Ocean Energy Devices

International audienceAs ocean wave and tidal stream technologies approach commercial readiness, grid operators need to assess the impact a wave or tidal device will have on the electrical grid under both normal and fault conditions. In order to achieve this, it will be necessary for each device developer to supply dynamic models of their device to the grid operator. A generic modelling approach is proposed to facilitate the integration of ocean energy devices into the electrical grid, from the perspective of both device developers and grid operators. This paper outlines issues surrounding dynamic modelling for ocean energy devices, and proposes a generic model structure based on data obtained from a recent survey of device developers. The proposed model structure would simulate the power flow through a device using generic parameters which can be obtained from empirical test data and equipment specifications

A novel live-attenuated vaccine candidate for mayaro Fever.

Mayaro virus (MAYV) is an emerging, mosquito-borne alphavirus that causes a dengue-like illness in many regions of South America, and which has the potential to urbanize. Because no specific treatment or vaccine is available for MAYV infection, we capitalized on an IRES-based approach to develop a live-attenuated MAYV vaccine candidate. Testing in infant, immunocompetent as well as interferon receptor-deficient mice demonstrated a high degree of attenuation, strong induction of neutralizing antibodies, and efficacy against lethal challenge. This vaccine strain was also unable to infect mosquito cells, a major safety feature for a live vaccine derived from a mosquito-borne virus. Further preclinical development of this vaccine candidate is warranted to protect against this important emerging disease

Retrospective analysis of patients’ experience to intravesical Bacillus Calmette-Guerin (BCG)

Why? • Gold standard • Bladder cancer incidence rates are highest in developed countries, especially Northern America and Europe • BCG treatment induction & maintenance has significant benefits, but also has significant side effects that tend to be seen within the first 12 months of treatment • To analyse the reasons for treatment interruption in everyday clinical practice in a large district hospita