NEISKORIŠTENI POTENCIJAL I VISOKOTEHNOLOŠKA TRGOVINA: SLUČAJ IZVOZA ZEMALJA ASEAN-6

This study aims to quantify the impact of untapped export potential on ASEAN-6 countries’ high-tech exports for the 2006-2016 period. Our innovative aspect sheds new light on the relationship between the untapped export potential in the previous year and export performance in the current year. Using a system GMM estimator, we found several significant results. Firstly, untapped export potential in the last year has a positive impact on ASEAN-6 countries’ high-tech exports in the current year. Secondly, the effect of untapped export potential on ASEAN-6 countries’ high-tech exports depends on supply competencies (ASEAN-6 countries’ human capital and research and development capability) and the bilateral linkage (importing countries’ trade barriers and institutional similarity between ASEAN-6 countries and importing countries). Thirdly, supply competencies are the most important when ASEAN-6 countries export high-tech goods to high-income countries. In contrast, the bilateral linkage is the most crucial when ASEAN-6 countries ship high-tech products to low-income countries. Measures to enhance human capital, upgrade research and development capability, promote trade liberalization, and minimize the institutional distance with the trading partners are the remedy for ASEAN-6 countries to tap the untapped potential.Ova studija ima za cilj kvantificirati utjecaj neiskorištenog izvoznog potencijala na visokotehnološki izvoz zemalja ASEAN-6 za razdoblje 2006.-2016. Naš inovativni aspekt baca novo svjetlo na odnos između neiskorištenog izvoznog potencijala u prethodnoj godini i izvoznih rezultata u tekućoj godini. Koristeći sustav GMM procjenitelja, pronašli smo nekoliko značajnih rezultata. Prvo, neiskorišteni izvozni potencijal u prošloj godini ima pozitivan učinak na visokotehnološki izvoz zemalja ASEAN-6 u tekućoj godini. Drugo, učinak neiskorištenog izvoznog potencijala na visokotehnološki izvoz zemalja ASEAN-6 ovisi o opskrbnim kompetencijama (ljudski kapital i sposobnost istraživanja i razvoja u zemljama ASEAN-6) i bilateralnoj povezanosti (trgovinske prepreke zemalja uvoznica i institucionalna sličnost između zemlje ASEAN-6 i zemlje uvoznice). Treće, kompetencije u opskrbi su najvažnije kada zemlje ASEAN-6 izvoze robu visoke tehnologije u zemlje s visokim dohotkom. Nasuprot tome, bilateralna veza je najvažnija kada zemlje ASEAN-6 isporučuju visokotehnološke proizvode u zemlje s niskim prihodima. Mjere za poboljšanje ljudskog kapitala, nadogradnju istraživačkih i razvojnih sposobnosti, promicanje liberalizacije trgovine i smanjenje institucionalne udaljenosti s trgovinskim partnerima, lijek su za zemlje ASEAN-6 da iskoriste neiskorišteni potencijal

GC-MS analysis and cytotoxic activity of the n-hexane fraction from Curcuma sahuynhensis Škornick. & N.S.Lý leaves collected in Vietnam

Curcuma sahuynhensis Škornick. & N.S.Lý is an endemic plant in Vietnam that has been used by the Sa Huynh people as a spice and medicine to cure illnesses linked to digestive disorders. Very little information is available so far about the chemical composition and biological effects of C. sahuynhensis. To find new pharmaceutical ingredients, the in vitro cytotoxic effect and the chemical profile of C. sahuynhensis leaf extract were investigated. In this study, the percolation method and liquid-liquid dispersion technique were used to extract dry sample powder. The chemical composition was detected by gas chromatography-mass spectrometry (GC-MS). The Sulforhodamine B and MTT methods were used to determine the cytotoxic activity. The chemical composition analysis showed that the leaf extract contained 14 components. The major components in the n-hexane extract were 6,10,14-trimethylpentadecan-2-one, phytol, 1-ethylbutyl hydroperoxide, isoborneol, 1-methylpentyl hydroperoxide, and neophytadiene. On human cancer cell lines, namely MFC-7, SK-LU-1, Hela, MKN-7, and HL-60, the leaf extract showed dose-dependent cytotoxic activity, with IC50 values ranging from 221.70±10.24 to 369.42±10.60 ?g/mL. The present study provides significant information on the chemical components and cytotoxic effects of the n-hexane extract from C. sahuynhensis leaves. The findings will continue to be crucial in future research on the evaluation of secondary metabolite compound analysis for cancer therapeutic effects

Factors affecting the creativity of high school students

Creativity is a vital personality quality of each individual. Each person has their potential for creativity, and it can be nurtured and developed in an appropriate and safe environment. The purpose of the study was to find out which factors from schools and students themselves affect creativity as well as the association between creativity and age, gender and giftedness of students, which then a basis to adjust and establish appropriate methods from schools, families, and students themselves to develop elements and their creativity. The study was conducted on 108 high school students in three grades from giftedness and non-giftedness schools. The data was collected through a survey method using a self-constructed questionnaire and drawing creativity test TCT-DP to determine students' creativity levels and personal information. The study's finding, which uses mathematical methods and one-way analysis of variance, reveals that factors affecting elements and creativity level are objective factors including education environment from school; behavior of teachers, and subjective factors including interests, perspectives, and thoughts of students. It was also found that there were no significant differences in the components of creativity and creativity among students in different grades, gender, and groups of giftedness schools

Synthesis, crystal structure and Hirshfeld surface analysis of 4-[3-(4-hy-droxy-phen-yl)-4,5-di-hydro-1H-pyrazol-5-yl]-2-meth-oxy-phenol monohydrate.

In the title pyrazoline derivative, C16H16N2O3·H2O, the pyrazoline ring has an envelope conformation with the substituted sp 2 C atom on the flap. The pyrazoline ring makes angles of 86.73 (12) and 13.44 (12)° with the tris-ubstituted and disubstituted benzene rings, respectively. In the crystal structure, the mol-ecules are connected into chains running in the b-axis direction by O-H⋯N hydrogen bonding. Parallel chains inter-act through N-H⋯O hydrogen bonds and π-π stacking of the tris-ubstituted phenyl rings. The major contribution to the surface contacts are H⋯H contacts (44.3%) as concluded from a Hirshfeld surface analysis

The Epidemiology of Interpandemic and Pandemic Influenza in Vietnam, 2007–2010: The Ha Nam Household Cohort Study I

Prospective community-based studies have provided fundamental insights into the epidemiology of influenza in temperate regions, but few comparable studies have been undertaken in the tropics. The authors conducted prospective influenza surveillance and intermittent seroprevalence surveys in a household-based cohort in Vietnam between December 2007 and April 2010, resulting in 1,793 person-seasons of influenza surveillance. Age- and sex-standardized estimates of the risk of acquiring any influenza infection per season in persons 5 years of age or older were 21.1% (95% confidence interval: 17.4, 24.7) in season 1, 26.4% (95% confidence interval: 22.6, 30.2) in season 2, and 17.0% (95% confidence interval: 13.6, 20.4) in season 3. Some individuals experienced multiple episodes of infection with different influenza types/subtypes in the same season (n = 27) or reinfection with the same subtype in different seasons (n = 22). The highest risk of influenza infection was in persons 5–9 years old, in whom the risk of influenza infection per season was 41.8%. Although the highest infection risk was in school-aged children, there were important heterogeneities in the age of infection by subtype and season. These heterogeneities could influence the impact of school closure and childhood vaccination on influenza transmission in tropical areas, such as Vietnam

CHẾ TẠO VÀ TÍNH CHẤT CỦA VẬT LIỆU TỔ HỢP GRAPHENE – ỐNG NANO CÁCBON – HẠT NANO VÀNG

In this work, a composite nanomaterial consisting of graphene (Gr), double-wall carbon nanotube (DWCNTs) and gold nanoparticles (AuNPs), designated as DWCNTs-AuNPs-Gr was synthesized via the thermal chemical vapour deposition technique. The morphology and electrical and electrochemical properties of the material were characteried by using field emission scanning electron microscopy, Raman spectroscopy, four-probe sheet resistance measurement, and cyclic voltammetry (CV). The average sheet resistance value of DWCNTs-AuNPs-Gr is 549 W/sq, 2.3 times lower than that of graphene. The current response of a DWCNTs-AuNPs-Gr-modified electrode in a 2 mM K3[Fe(CN)6]/K4[Fe(CN)6] solution with 0.1 M PBS is 15.79 µA, 1.48 times higher than that of a graphene-modified electrode and 2.57 times higher than that of a bare electrode. The DWCNTs-AuNPs-Gr material can be used for electrochemical biosensors to detect various bioelements.Trong công trình này, màng tổ hợp của vật liệu graphene (Gr) – ống nano cácbon hai tường (DWCNT) và hạt nano kim loại vàng (AuNPs) (DWCNT-AuNPs-Gr) đã được chế tạo bằng phương pháp lắng đọng pha hơi nhiệt hóa học (CVD). Hình thái học bề mặt và các tính chất điện, điện hóa của vật liệu tổ hợp đã được khảo sát thông qua kính hiển vi điện tử quét phát xạ trường, phổ Raman, điện trở bốn mũi dò và kỹ thuật quét thế vòng (CV). Với nồng độ DWCNTs 0,3 g/L và tốc độ quay phủ 4000 vòng/phút, vật liệu DWCNTs-AuNPs-Gr có điện trở bề mặt giảm 2,3 lần so với màng Gr và đạt khoảng 549 W/sq; dòng đỉnh đáp ứng trong dung dịch 2 mM K3[Fe(CN)6]/K4[Fe(CN)6] trong 0,1 M PBS đạt 15,79 µA tại 50 mV/s, cao gấp 1,48 lần so với điện cực biến tính màng Gr và gấp 2,57 lần so với điện cực trần. Vật liệu DWCNTs-AuNPs-Gr có tiềm năng ứng dụng trong cảm biến điện hóa để phát hiện các phần tử sinh học khác nhau

Discrepancies in Infectivity of Flavivirus and SARS-CoV-2 Clinical Samples: An Improved Assay for Infectious Virus Shedding and Viremia Assessment

Infectivity and neutralizing antibody titers of flavivirus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are frequently measured using the conventional plaque assay. While the assay is useful in the determination of infectivity, conventional plaque assays generally possess lower sensitivity and are time-consuming compared to nucleic acid amplification tests. In this study, a microcrystalline cellulose (MCC), Avicel, was evaluated as an alternative to the conventional virus overlay medium, methylcellulose, for a plaque assay. The plaque assay was performed using dengue and COVID-19 clinical samples and laboratory-established flavivirus and SARS-CoV-2 strains. In virus titration of clinical samples, the plaques were significantly larger, and the virus titers were higher when Avicel MCC-containing overlay medium was used than with conventional methylcellulose overlay medium. In addition, for some clinical samples and laboratory virus strains, infectious particles were detected as plaques in the Avicel MCC-containing medium, but not in the conventional methylcellulose medium. The results suggest that the viremia titer determined using the new overlay medium containing Avicel MCC may better reflect the innate infectious and plaque-forming capabilities of clinical samples and better reflect virus infectivity