Vanishing Cosmological Constant in Modified Gauss-Bonnet Gravity with Conformal Anomaly

We consider dark energy cosmology in a de Sitter universe filled with quantum conformal matter. Our model represents a Gauss-Bonnet model of gravity with contributions from quantum effects. To the General Relativity action an arbitrary function of the GB invariant, f(G), is added, and taking into account quantum effects from matter the cosmological constant is studied. For the considered model the conditions for a vanishing cosmological constant are considered. Creation of a de Sitter universe by quantum effects in a GB modified gravity is discussed.Comment: 8 pages latex, 1 figure. To appear in Int. J. Mod. Phys.

Controlling pulse propagation in optical fibers through nonlinearity and dispersion management

In case of the nonlinear Schr\"odinger equation with designed group velocity dispersion, variable nonlinearity and gain/loss; we analytically demonstrate the phenomenon of chirp reversal crucial for pulse reproduction. Two different scenarios are exhibited, where the pulses experience identical dispersion profiles, but show entirely different propagation behavior. Exact expressions for dynamical quasi-solitons and soliton bound-states relevant for fiber communication are also exhibited.Comment: 4 pages, 5 eps figure

Producción de huevos en Eurypodius latreillii Guérin, 1828 (Decapoda: Majidae) en el Estrecho de Magallanes, sur de Chile

Egg production and reproductive investment were studied in the spider crab Eurypodius latreillii from the Straits of Magellan, southern Chile. A total of 66 ovigerous females were analyzed, ranging in size from 29.0 to 62.9 mm carapace length. E. latreillii produced up to 15886 embryos, and clutch size increased with maternal size. Initial egg size was large (0.162 mm3), and the embryo volume increase during the incubation period was 32 %. Brood mortality was substantial (83 %), and since egg volume increase could not compensate for the egg loss, average egg mass volume decreased considerably during embryogenesis. The average brood mass at laying accounted for 13 % of the maternal body mass (on a wet mass basis), and this value coincides with previous findings concerning energy allocation for egg production in other brachyuran crabs. In general, our data regarding E. latreillii correspond well with those from spider crab species inhabiting the northern hemisphere. The large egg size of E. latreillii compared with majids from other geographical regions may be an indication of a latitudinal gradient in the reproductive biology of majid crabs. Future studies with spider crabs from the southern hemisphere are desirable to substantiate this assumption.Se estudió la producción de huevos y la inversión reproductiva del cangrejo araña Eurypodius latreillii proveniente del Estrecho de Magallanes, sur de Chile. Se analizaron un total de 66 hembras ovígeras con un rango de tamaños entre 29,0 y 62,9 mm de longitud de caparazón. E. latreilli produjo hasta un máximo de 15886 embriones, y el número de huevos aumentó con el tamaño de la hembra. El tamaño inicial del huevo fue grande (0,162 mm3) y el aumento del volumen embrionario durante el período de incubación fue de 32 %. La mortalidad de huevos fue considerable (83 %), y como el aumento en el volumen de los huevos no pudo compensar la pérdida de huevos, el promedio del volumen de la masa de los huevos disminuyó de forma considerable durante la embriogénesis. La masa de huevos representó un 13 % de la masa corporal de la madre, y este valor coincide con observaciones previas sobre la asignación de energía para la producción de huevos en otros braquiuros. En general, nuestros datos sobre E. latreillii concuerdan con datos sobre especies del cangrejo araña del hemisferio norte. El tamaño grande de huevos de E. latreillii comparado con Majidae de otras regiones geográficas podría ser interpretado como una indicación de un gradiente latitudinal en la biología reproductiva de cangrejos májidos. Para corroborar esta interpretación se requerirían estudios futuros con cangrejos araña del hemisferio sur

Microscopic analytical theory of a correlated, two-dimensional N-electron gas in a magnetic field

We present a microscopic, analytical theory describing a confined N-electron gas in two dimensions subject to an external magnetic field. The number of electrons N and strength of the electron-electron interaction can be arbitrarily large, and all Landau levels are included implicitly. A possible connection with the Integer and Fractional Quantum Hall Effects is proposed.Comment: The revised version contains minor changes to text. To be published in J. Phys: Condens. Mat

Shaping the edge radial electric field to create shearless transport barriers in tokamaks

In tokamak-confined plasmas, particle transport can be reduced by modifying the radial electric field. In this paper, we investigate the influence of both a well-like and a hill-like shaped radial electric field profile on the creation of shearless transport barriers (STBs) at the plasma edge, which are a type of barrier that can prevent chaotic transport and are related to the presence of extreme values in the rotation number profile. For that, we apply an ExB drift model to describe test particle orbits in large aspect-ratio tokamaks. We show how these barriers depend on the electrostatic fluctuation amplitudes and on the width and depth (height) of the radial electric field well-like (hill-like) profile. We find that, as the depth (height) increases, the STB at the plasma edge becomes more resistant to fluctuations, enabling access to an improved confinement regime that prevents chaotic transport. We also present parameter spaces with the radial electric field parameters, indicating the STB existence for several electric field configurations at the plasma edge, for which we obtain a fractal structure at the barrier/non-barrier frontier, typical of quasi-integrable Hamiltonian systems.Comment: 12 pages and 8 figure

Adiabatic Compression of Soliton Matter Waves

The evolution of atomic solitary waves in Bose-Einstein condensate (BEC) under adiabatic changes of the atomic scattering length is investigated. The variations of amplitude, width, and velocity of soliton are found for both spatial and time adiabatic variations. The possibility to use these variations to compress solitons up to very high local matter densities is shown both in absence and in presence of a parabolic confining potential.Comment: to appear in J.Phys.

New Distance-Based approach for Genome-Wide Association Studies

With the raise of genome-wide association studies (GWAS), the analysis of typical GWAS data sets with thousands of potentially predictive single nucleotide-polymorphisms (SNPs) has become crucial in Biomedicine research. Here, we propose a new method to identify SNPs related to disease in case-control studies. The method, based on genetic distances between individuals, takes into account the possible population substructure, and avoids the issues of multiple testing. The method provides two ordered lists of SNPs; one with SNPs which minor alleles can be considered risk alleles for the disease, and another one with SNPs which minor alleles can be considered as protective. These two lists provide a useful tool to help the researcher to decide where to focus attention in a first stage

ExB drift particle transport in tokamaks

In tokamaks, modification of the plasma profiles can reduce plasma transport, improving particle confinement. However, this improvement is still not completely understood. In this work, we consider a drift wave test particle model to investigate the influence of the electric and magnetic field profiles on plasma transport. Test particle orbits subjected to ExB drift are numerically integrated and their transport coefficient is obtained. We conclude that sheared profiles reduce particle transport, even for high amplitude perturbations. In particular, nonmonotonic electric and magnetic fields produce shearless transport barriers, which are particularly resistant to perturbations and reduce even more the transport coefficient.Comment: 10 pages, 9 figures, 1 table. Published in Brazilian Journal of Physic

S-adenosyl-L-methionine protects the liver against the cholestatic, cytotoxic, and vasoactive effects of leukotriene D4: a study with isolated and perfused rat liver

Cysteinyl-leukotrienes can cause cholestasis and liver damage when administered at nanomolar concentrations. Using the isolated and perfused rat liver we analyzed whether S-adenosyl-L-methionine (SAMe) may protect this organ against the noxious effects of leukotriene-D4 (LTD4). We observed that a 2 nmol bolus of this compound decreased bile flow (-12.6% +/- 1.6%, P < .02), and bile salt excretion (-23.5% +/- 2.2%, P < .02; both compared with baseline values), caused the release of glutamic-oxaloacetic transaminase (GOT) and lactic dehydrogenase (LDH) to the hepatic effluent, and increased significantly the perfusion pressure as compared with a control group not receiving LTD4 (6.0 +/- 1.1 vs. 0.2 +/- 0.02 mm hg, respectively; P < .001). The cholestatic effect of LTD4 was attenuated by infusion of SAMe which, at rates of 67 and 100 microg/min, totally prevented the decrease in bile salt excretion. Likewise, in SAMe infused livers, the release to the effluent of GOT and LDH was lower than in the group receiving LTD4 only, and was even lower than in the control group. We also found that the increase in perfusion pressure induced by LTD4 was prevented by SAMe in a dose-dependent manner. Of interest, SAMe increased the biliary excretion of the eicosanoid in a dose-related fashion. We conclude that SAMe reverts the cholestatic, cytotoxic, and hemodynamic effects of LTD4 on the liver, and that these protective effects might be partly because of a stimulation of the biliary excretion of the leukotriene

Functional Interplay of Type-2 Corticotrophin Releasing Factor and Dopamine Receptors in the Basolateral Amygdala-Medial Prefrontal Cortex Circuitry

Background: Basolateral amygdala (BLA) excitatory projections to medial prefrontal cortex (PFC) play a key role controlling stress behavior, pain, and fear. Indeed, stressful events block synaptic plasticity at the BLA-PFC circuit. The stress responses involve the action of corticotrophin releasing factor (CRF) through type 1 and type 2 CRF receptors (CRF1 and CRF2). Interestingly, it has been described that dopamine receptor 1 (D1R) and CRF peptide have a modulatory role of BLA-PFC transmission. However, the participation of CRF1 and CRF2 receptors in BLA-PFC synaptic transmission still is unclear. Methods: We used in vivo microdialysis to determine dopamine and glutamate (GLU) extracellular levels in PFC after BLA stimulation. Immunofluorescence anatomical studies in rat PFC synaptosomes devoid of postsynaptic elements were performed to determine the presence of D1R and CRF2 receptors in synaptical nerve endings. Results: Here, we provide direct evidence of the opposite role that CRF receptors exert over dopamine extracellular levels in the PFC. We also show that D1R colocalizes with CRF2 receptors in PFC nerve terminals. Intra-PFC infusion of antisauvagine-30, a CRF2 receptor antagonist, increased PFC GLU extracellular levels induced by BLA activation. Interestingly, the increase in GLU release observed in the presence of antisauvagine-30 was significantly reduced by incubation with SCH23390, a D1R antagonist. Conclusion: PFC CRF2 receptor unmasks D1R effect over glutamatergic transmission of the BLA-PFC circuit. Overall, CRF2 receptor emerges as a new modulator of BLA to PFC glutamatergic transmission, thus playing a potential role in emotional disorders. Keywords: CRF2 receptor; D1 receptor; dopaminergic transmission; glutamatergic transmission; prefrontal cortex