717 research outputs found

    Redundancy Strategies for a High Splitting Optically Amplified Passive Optical Network

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    Copyright IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.High splitting, optically amplified, passive optical networks (SuperPONs) are investigated in terms of redundancy provision and protection mechanisms. Options for redundancy, including the important special case of dual homing, are detailed, and it is determined as to which of these options (duplication of the feeder and first distribution section, and N+1 protection of the optical amplifiers in the amplified splitter) would be required to be provided to all attached users to facilitate appropriate availability of the basic telephony service. The distributed amplified splitter dual homing solution is found to outperform the single amplified splitter solution in terms of its survivability. The protection mechanisms necessary to automatically switch to the redundant provision are discussed and it is seen that with the aid of suitable regular precautionary procedures protection switching can generally be provided rapidly (<50 ms). Finally, an availability, and cost versus availability, study confirms the aforementioned redundancy assessment for fiber-to-the-home (FTTH) implementations, but shows fiber-to-the-curb (FTTC) as needing additional redundancyPeer reviewe

    Designing a Microfluidic Sorting Network with Heat Treated Plastic

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    A microfluidic device is necessary to sort nanodiamonds based on their luminescence. We explored utilizing the repeatable shrinkage of heat treated Shrinky Dink (polystyrene) sheets in an effort to find an easier, cheaper alternative to the traditional photolithography process. Our work found encouraging results but the plastic’s capabilities must be further studied to decisively determine its usefulness.https://digitalcommons.hamilton.edu/posters/1000/thumbnail.jp

    Stakeholder Perception in the Organizational Environment Focusing on Behavior

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    Behavior has meaning for the organizational climate, leading to studies such as this related to stakeholder perception in the institutional environment. This task is based on the Behavioral Management Theory and the additional concepts required. It was sought to know the relation of the intervening factors, from the method of case study of qualitative-quantitative nature, in order to establish comparisons and to produce the results. The general objective is to study the stakeholder perception process in the organizational environment focused on the behavioral effect and it has as specific objectives to treat and identify the relationship of the intervening factors with the organizational climate in the face of data collected among the consulted, to perform the SWOT on the positioning of individuals in the organizational environment and how this perception is characterized in the face of the organizational climate present in the consulted organ. The research indicates that the majority of respondents stated that the organizational climate present in the organ consulted satisfactory, propitiates the good organizational environment in the organ. Confrontation between the theoretical indicatives and the reality identified in the institutional environment allows to affirm that in fact there is internal influence, such as the motivation and external organization, as the possibility of losing the employee attracted by other opportunities outside the institution. Analysis allows to identify the need for physical improvement of the professional space, and in the interaction between stakeholders; redistribution of work that avoids overload; but the motivation and good internal relation between the individuals surpass the expectation. This work interests the managers in public organs and other interested in the subject here treated

    Innovating Management Control by Dynamic Analysis of Pareto in a Hotel Business

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    This paper deals with the Pareto Analysis of problems observed and criticized by clients in a hotel establishment in the municipality of Porto Velho, capital of the State of Rondocirc;nia. The general objective of the research is to study the use of Pareto Analysis in these problems that annoy the clients; (1), to group the data in descending order of frequency and to calculate the cumulative values (2), and indicating innovation for managerial control through a tool for Pareto Analysis in a dynamical way (3). The methodology of the qualitative-quantitative approach, of an exploratory nature, is adopted; the bibliographic survey and the field research are applied in support of the case study. Through the database system that the company under study possesses, the data necessary to be used in the Pareto Analysis are obtained, completing the first specific objective; the grouping of these data in descending order of absolute frequency, the calculation of the cumulative values, the preparation of the Pareto Diagram and the analysis carried out successfully completed the second specific objective; and finally the study is finished with the creation of a tool that allows a more dynamic analysis of the scenario in which the company is inserted, as a proposal of innovation for the institution to perform its practical and dynamic analyzes, useful in decision making. This study is a contribution of the academy to managers who work with complex decisions in hotel or related establishments interested in customer satisfaction

    Quantifying the effects of antibiotic treatment on the extracellular polymer network of antimicrobial resistant and sensitive biofilms using multiple particle tracking

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    Novel therapeutics designed to target the polymeric matrix of biofilms requires innovative techniques to accurately assess their efficacy. Here, multiple particle tracking (MPT) was developed to characterize the physical and mechanical properties of antimicrobial resistant (AMR) bacterial biofilms and to quantify the effects of antibiotic treatment. Studies employed nanoparticles (NPs) of varying charge and size (40–500 nm) in Pseudomonas aeruginosa PAO1 and methicillin-resistant Staphylococcus aureus (MRSA) biofilms and also in polymyxin B (PMB) treated Escherichia coli biofilms of PMB-sensitive (PMBSens) IR57 and PMB-resistant (PMBR) PN47 strains. NP size-dependent and strain-related differences in the diffusion coefficient values of biofilms were evident between PAO1 and MRSA. Dose-dependent treatment effects induced by PMB in PMBSens E. coli biofilms included increases in diffusion and creep compliance (P < 0.05), not evident in PMB treatment of PMBR E. coli biofilms. Our results highlight the ability of MPT to quantify the diffusion and mechanical effects of antibiotic therapies within the AMR biofilm matrix, offering a valuable tool for the pre-clinical screening of anti-biofilm therapies

    Formulation and Evaluation of Cephalexin Extended-release Matrix Tablets Using Hydroxy Propyl Methyl Cellulose as Rate-controlling Polymer

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    The present investigation reports the design and evaluation of six-hour extended release film-coated matrix tablets of cephalexin using different grades of hydrophilic polymer hydroxypropylmethylcellulose (HPMC) employing direct compression method. The preformulation studies performed included the physical compatibility studies, Differential Scanning Calorimetry analysis, drug characterization using Fourier Transform Infra Red spectroscopic analysis and particle size analysis using sieve method. The tablets were evaluated for weight variation, hardness, thickness and friability. Results of the studies indicate that the polymers used have significant release-retarding effect on the formulation. The dissolution profile comparison of the prepared batches P1 to P8 and market preparation (Sporidex AF 375) was done by using Food and Drug Administration-recommended similarity factor (f2) determination. The formulation P8 (10% HPMC K4M, 15% HPMC 15cps) with a similarity factor (f2) of 77.75 was selected as the optimized formulae for scale-up batches. The dissolution data of the best formulation P8 was fitted into zero order, first order, Higuchi and Korsemeyer-Peppas models to identify the pharmacokinetics and mechanism of drug release. The results of the accelerated stability study of best formulation P8 for three months revealed that storage conditions were not found to have made any significant changes in final formulation F3. The release of cephalexin was prolonged for 6 h by using polymer combinations of HPMC and a twice daily matrix tablet was formulated

    Generational Differences and Determinants of Purchase Behavior towards Sustainable Clothing in a Developing Economy

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    The fashion industry contributes significant plastic pollution and greenhouse gas emissions globally. One approach to minimize the industry’s environmental impact is through a shift to sustainable clothing. This study determined the predictors of purchase behavior towards sustainable clothing in a developing economy, which is the Philippines. Furthermore, this paper compared Filipinos from Generations X and Z. Results of a multiple regression analysis from a sample of 212 participants in an online survey showed that generation and environmental knowledge predicted the purchase of sustainable clothing. Moreover, Gen Z scored higher in environmental knowledge and purchase of sustainable clothing. The findings provide insights on increasing the usage of sustainable clothing, which can significantly reduce the environmental impact of the fashion industry

    From d-wave to s-wave pairing in the iron-pnictide superconductor (Ba,K)Fe2As2

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    The nature of the pairing state in iron-based superconductors is the subject of much debate. Here we argue that in one material, the stoichiometric iron pnictide KFe2As2, there is overwhelming evidence for a d-wave pairing state, characterized by symmetry-imposed vertical line nodes in the superconducting gap. This evidence is reviewed, with a focus on thermal conductivity and the strong impact of impurity scattering on the critical temperature Tc. We then compare KFe2As2 to Ba0.6K0.4Fe2As2, obtained by Ba substitution, where the pairing symmetry is s-wave and the Tc is ten times higher. The transition from d-wave to s-wave within the same crystal structure provides a rare opportunity to investigate the connection between band structure and pairing mechanism. We also compare KFe2As2 to the nodal iron-based superconductor LaFePO, for which the pairing symmetry is probably not d-wave, but more likely s-wave with accidental line nodes

    Long‐Term Outcomes of Cardiac Resynchronization Therapy Using Apical Versus Nonapical Left Ventricular Pacing

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    Background Experimental evidence indicates that left ventricular (LV) apical pacing is hemodynamically superior to nonapical LV pacing. Some studies have shown that an LV apical lead position is unfavorable in cardiac resynchronization therapy. We sought to determine whether an apical LV lead position influences cardiac mortality after cardiac resynchronization therapy. Methods and Results In this retrospective observational study, the primary end point of cardiac mortality was assessed in relation to longitudinal (basal, midventricular, or apical) and circumferential (anterior, lateral, or posterior) LV lead positions, as well as right ventricular (apical or septal), assigned using fluoroscopy. Lead positions were assessed in 1189 patients undergoing cardiac resynchronization therapy implantation over 15 years. After a median follow‐up of 6.0 years (interquartile range: 4.4–7.7 years), an apical LV lead position was associated with lower cardiac mortality than a nonapical position (adjusted hazard ratio: 0.74; 95% confidence interval, 0.56–0.99) after covariate adjustment. There were no differences in total mortality or heart failure hospitalization. Death from pump failure was lower with apical than nonapical positions (adjusted hazard ratio: 0.69; 95% confidence interval, 0.51–0.94). Compared with a basal position, an apical LV position was also associated with lower risk of sudden cardiac death (adjusted hazard ratio: 0.34; 95% confidence interval, 0.13–0.93). No differences emerged between circumferential LV lead positions or right ventricular positions with respect to any end point. Conclusions In recipients of cardiac resynchronization therapy, an apical LV lead position was associated with better long‐term cardiac survival than a nonapical position. This effect was due to a lower risk of pump failure and sudden cardiac death

    Quasiparticle excitation in and around the vortex core of underdoped YBa_2Cu_4O_8 studied by site-selective NMR

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    We report a site-selective ^{17}O spin-lattice relaxation rate T_1^{-1} in the vortex state of underdoped YBa_2Cu_4O_8. We found that T_1^{-1} at the planar sites exhibits an unusual nonmonotonic NMR frequency dependence. In the region well outside the vortex core, T_1^{-1} cannot be simply explained by the density of states of the Doppler-shifted quasiparticles in the d-wave superconductor. Based on T_1^{-1} in the vortex core region, we establish strong evidence that the local density of states within the vortex core is strongly reduced.Comment: 5 pages, 3 figure
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