Occurrence of and attempts to eradicate grape phylloxera (Homoptera: Phylloxeridae) in British Columbia

oai:jesbc.journals.sfu.ca:article/1817The chronological occurrence, survey methods, and eradication programs of the grape phylloxera, Phyiloxera vitifoliae (Fitch), in British Columbia are described. The insect was first found in the Okanagan Valley in 1961. Though an eradication program at that time was apparently successful, the insect reappeared in 1971. It is now well established in the area. The pest was accidentally introduced on imported vines

The elements of a computational infrastructure for social simulation

Applications of simulation modelling in social science domains are varied and increasingly widespread. The effective deployment of simulation models depends on access to diverse datasets, the use of analysis capabilities, the ability to visualize model outcomes and to capture, share and re-use simulations as evidence in research and policy-making. We describe three applications of e-social science that promote social simulation modelling, data management and visualization. An example is outlined in which the three components are brought together in a transport planning context. We discuss opportunities and benefits for the combination of these and other components into an e-infrastructure for social simulation and review recent progress towards the establishment of such an infrastructure

Copper-catalyzed functionalization of enynes.

From Europe PMC via Jisc Publications RouterHistory: ppub 2020-10-01, epub 2020-10-07Publication status: PublishedFunder: Engineering and Physical Sciences Research Council; Grant(s): EP/P001386/1, EP/M005062/1The copper-catalyzed functionalization of enyne derivatives has recently emerged as a powerful approach in contemporary synthesis. Enynes are versatile and readily accessible substrates that can undergo a variety of reactions to yield densely functionalized, enantioenriched products. In this perspective, we review copper-catalyzed transformations of enynes, such as boro- and hydrofunctionalizations, copper-mediated radical difunctionalizations, and cyclizations. Particular attention is given to the regiodivergent functionalization of 1,3-enynes, and the current mechanistic understanding of such processes

An approximate model for cancellous bone screw fixation

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Taylor & Francis.This paper presents a finite element (FE) model to identify parameters that affect the performance of an improved cancellous bone screw fixation technique, and hence potentially improve fracture treatment. In cancellous bone of low apparent density, it can be difficult to achieve adequate screw fixation and hence provide stable fracture fixation that enables bone healing. Data from predictive FE models indicate that cements can have a significant potential to improve screw holding power in cancellous bone. These FE models are used to demonstrate the key parameters that determine pull-out strength in a variety of screw, bone and cement set-ups, and to compare the effectiveness of different configurations. The paper concludes that significant advantages, up to an order of magnitude, in screw pull-out strength in cancellous bone might be gained by the appropriate use of a currently approved calcium phosphate cement

Teamworking under Lean in UK public services: lean teams and team targets in Her Majesty's Revenue & Customs (HMRC)

The authors of The Machine that Changed the World were in no doubt about the importance of teamworking in lean production: ‘in the end’, they say [Womack, J., Jones, D, & Roos, D. (1990). The machine that changed the world. New York: Rawson Associates, p. 99], ‘it is the dynamic work team that emerges as the heart of the lean factory’. It is with this bold statement in mind that we seek to explore and develop our conceptual and practical understanding of how teamworking operates under Lean. We examine these issues in the context of a high-profile case of Lean implementation in the UK public sector, the Pacesetter programme of the UK's tax assessment and collection service, Her Majesty's Revenue & Customs (HMRC). We find that although the teams themselves were ostensibly set up on a lean basis, they were largely unable to operate as such as a result of the pressures they faced to meet their work targets. The operation of the teams thus retained, and was shaped by, characteristics of the pre-existing ‘target-based’ mode of teamworking. This, in turn, suggests particular ways in which we might better understand how Lean interacts with the context or environment into which it is introduced. These findings also to some degree run counter to the overwhelmingly negative account of Lean put forward in other recent studies of HMRC [e.g. Carter, B., Danford, A., Howcroft, D., Richardson, H., Smith, A., & Taylor, P. (2013a). Taxing times: Lean working and the creation of (in)efficiencies in HM Revenue and Customs. Public Administration, 91, 83–97]

Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles

The expedient assembly of complex, natural product-like small molecules can deliver new chemical entities with the potential to interact with biological systems and inspire the development of new drugs and probes for biology. Diversity-oriented synthesis is a particularly attractive strategy for the delivery of complex molecules in which the 3-dimensional architecture varies across the collection. Here we describe a folding cascade approach to complex polycyclic systems bearing multiple stereocentres mediated by reductive single electron transfer (SET) from SmI2. Simple, linear substrates undergo three different folding pathways triggered by reductive SET. Two of the radical cascade pathways involve the activation and functionalization of otherwise inert secondary alkyl and benzylic groups by 1,5-hydrogen atom transfer (HAT). Combination of SmI2, a privileged reagent for cascade reactions, and 1,5-HAT can lead to complexity-generating radical sequences that unlock access to diverse structures not readily accessible by other means

An evaluation of maternity care provided in three Sure Start Local Programmes in Islington. Summary report

This report summarises the key findings and recommendations. The methods and detailed findings are described in the full report and further analysis of the quantitative data is in a supplementary report “Detailed quantitative analysis and findings.” Both are available from Islington Sure Start