155 research outputs found
Thermal out-of-time-order correlators, KMS relations, and spectral functions
We describe general features of thermal correlation functions in quantum
systems, with specific focus on the fluctuation-dissipation type relations
implied by the KMS condition. These end up relating correlation functions with
different time ordering and thus should naturally be viewed in the larger
context of out-of-time-ordered (OTO) observables. In particular, eschewing the
standard formulation of KMS relations where thermal periodicity is combined
with time-reversal to stay within the purview of Schwinger-Keldysh functional
integrals, we show that there is a natural way to phrase them directly in terms
of OTO correlators. We use these observations to construct a natural causal
basis for thermal n-point functions in terms of fully nested commutators. We
provide several general results which can be inferred from cyclic orbits of
permutations, and exemplify the abstract results using a quantum oscillator as
an explicit example.Comment: 36 pages + appendices. v2: minor changes + refs added. v3: minor
changes, published versio
Spin coherent quantum transport of electrons between defects in diamond
The nitrogen-vacancy color center in diamond has rapidly emerged as an
important solid-state system for quantum information processing. While
individual spin registers have been used to implement small-scale diamond
quantum computing, the realization of a large-scale device requires development
of an on-chip quantum bus for transporting information between distant qubits.
Here we propose a method for coherent quantum transport of an electron and its
spin state between distant NV centers. Transport is achieved by the
implementation of spatial stimulated adiabatic Raman passage through the
optical control of the NV center charge states and the confined conduction
states of a diamond nanostructure. Our models show that for two NV centers in a
diamond nanowire, high fidelity transport can be achieved over distances of
order hundreds of nanometres in timescales of order hundreds of nanoseconds.
Spatial adiabatic passage is therefore a promising option for realizing an
on-chip spin quantum bus
Hysteresis Loop Effect on Coronal Index and Solar Flare Index During Solar Cycles 22 and 23
The hysteresis loop effect on the solar activity as coronal index (CI) and solar flare index (SFI) over cosmic ray intensity (CRI) at the low cut-off rigidities neutron monitoring station Oulu on the monthly basis data for the period January 1, 1986 to December 31, 2008 has been studied. It is observed that the shape of the hysteresis loops is varying from solar cycle 22 to 23. The hysteresis loops for solar cycle 23 are broad ovals whereas for solar cycle 22 are nearly flat. A complementary feature of the cosmic ray intensity decreases more rapidly as the increase in solar activity (coronal index and solar flare index). The positive solar polar magnetic parameter (A>0) and negative solar polar magnetic parameter (A<0) is representing the hysteresis loops
Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with preserved ejection fraction
Background-Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling. Organic nitrates reduce wave reflections acutely, but whether this is sustained chronically or affected by hydralazine coadministration is unknown. Methods and Results-We randomized 44 patients with heart failure with preserved ejection fraction in a double-blinded fashion to isosorbide dinitrate (ISDN; n=13), ISDN+hydralazine (ISDN+hydral; n=15), or placebo (n=16) for 6months. The primary end point was the change in reflection magnitude (RM; assessed with arterial tonometry and Doppler echocardiography). Secondary end points included change in left ventricular mass and fibrosis, measured with cardiac magnetic resonance imaging, and the 6-minute walk distance. ISDN reduced aortic characteristic impedance (mean baseline=0.15 [95% CI, 0.14-0.17], 3 months=0.11 [95% CI, 0.10-0.13], 6 months=0.10 [95% CI, 0.08-0.12] mmHg/mL per second; P=0.003) and forward wave amplitude (P-f, mean baseline=54.8 [95% CI, 47.6-62.0], 3 months=42.2 [95% CI, 33.2-51.3]; 6 months=37.0 [95% CI, 27.2-46.8] mmHg, P=0.04), but had no effect on RM (P=0.64), left ventricular mass (P=0.33), or fibrosis (P=0.63). ISDN+hydral increased RM (mean baseline=0.39 [95% CI, 0.35-0.43]; 3 months=0.31 [95% CI, 0.25-0.36]; 6 months=0.44 [95% CI, 0.37-0.51], P=0.03), reduced 6-minute walk distance (mean baseline=343.3 [95% CI, 319.2-367.4]; 6 months=277.0 [95% CI, 242.7-311.4] meters, P=0.022), and increased native myocardial T1 (mean baseline=1016.2 [95% CI, 1002.7-1029.7]; 6 months=1054.5 [95% CI, 1036.5-1072.3], P=0.021). A high proportion of patients experienced adverse events with active therapy (ISDN=61.5%, ISDN+hydral=60.0%; placebo=12.5%; P=0.007). Conclusions-ISDN, with or without hydralazine, does not exert beneficial effects on RM, left ventricular remodeling, or submaximal exercise and is poorly tolerated. ISDN+hydral appears to have deleterious effects on RM, myocardial remodeling, and submaximal exercise. Our findings do not support the routine use of these vasodilators in patients with heart failure with preserved ejection fraction
Supersymmetric States in Large N Chern-Simons-Matter Theories
In this paper we study the spectrum of BPS operators/states in N=2
superconformal U(N) Chern-Simons-matter theories with adjoint chiral matter
fields, with and without superpotential. The superconformal indices and
conjectures on the full supersymmetric spectrum of the theories in the large N
limit with up to two adjoint matter fields are presented. Our results suggest
that some of these theories may have supergravity duals at strong coupling,
while some others may be dual to higher spin theories of gravity at strong
coupling. For the N=2 theory with no superpotential, we study the
renormalization of R-charge at finite 't Hooft coupling using "Z-minimization".
A particularly intriguing result is found in the case of one adjoint matter.Comment: 53 pages, 18 figures. v2: improved numerics, additional comments
adde
On The Stability Of Non-Supersymmetric AdS Vacua
We consider two infinite families of Non-Supersymmetric vacua, called
Type 2) and Type 3) vacua, that arise in massive IIA supergravity with flux. We
show that both families are perturbatively stable. We then examine
non-perturbative decays of these vacua to other supersymmetric and
non-supersymmetric vacua mediated by instantons in the thin wall
approximation. We find that many decays are ruled out since the tension of the
interpolating domain wall is too big compared to the energy difference in AdS
units. In fact, within our approximations no decays of Type 2) vacua are
allowed, although some decays are only marginally forbidden. This can be
understood in terms of a "pairing symmetry" in the landscape which relate Type
2) vacua with supersymmetric ones of the same energy.Comment: 50 pages, Minor changes in section 2.2.
Adaptation of Microelectrode Array Technology for the Study of Anesthesia-Induced Neurotoxicity in the Intact Piglet Brain
Every year, millions of children undergo anesthesia for a multitude of procedures. However, studies in both animals and humans have called into question the safety of anesthesia in children, implicating anesthetics as potentially toxic to the brain in development. To date, no studies have successfully elucidated the mechanism(s) by which anesthesia may be neurotoxic. Animal studies allow investigation of such mechanisms, and neonatal piglets represent an excellent model to study these effects due to their striking developmental similarities to the human brain.
This protocol adapts the use of enzyme-based microelectrode array (MEA) technology as a novel way to study the mechanism(s) of anesthesia-induced neurotoxicity (AIN). MEAs enable real-time monitoring of in vivo neurotransmitter activity and offer exceptional temporal and spatial resolution. It is hypothesized that anesthetic neurotoxicity is caused in part by glutamate dysregulation and MEAs offer a method to measure glutamate. The novel implementation of MEA technology in a piglet model presents a unique opportunity for the study of AIN
Holographic Fermi and Non-Fermi Liquids with Transitions in Dilaton Gravity
We study the two-point function for fermionic operators in a class of
strongly coupled systems using the gauge-gravity correspondence. The gravity
description includes a gauge field and a dilaton which determines the gauge
coupling and the potential energy. Extremal black brane solutions in this
system typically have vanishing entropy. By analyzing a charged fermion in
these extremal black brane backgrounds we calculate the two-point function of
the corresponding boundary fermionic operator. We find that in some region of
parameter space it is of Fermi liquid type. Outside this region no well-defined
quasi-particles exist, with the excitations acquiring a non-vanishing width at
zero frequency. At the transition, the two-point function can exhibit non-Fermi
liquid behaviour.Comment: 52 pages, 6 figures. v3: Appendix F added showing numerical
interpolation between the near-horizon region and AdS4. Additional minor
comments also adde
Diamond nano-pillar arrays for quantum microscopy of neuronal signals
Modern neuroscience is currently limited in its capacity to perform long
term, wide-field measurements of neuron electromagnetics with nanoscale
resolution. Quantum microscopy using the nitrogen vacancy centre (NV) can
provide a potential solution to this problem with electric and magnetic field
sensing at nano-scale resolution and good biocompatibility. However, the
performance of existing NV sensing technology does not allow for studies of
small mammalian neurons yet. In this paper, we propose a solution to this
problem by engineering NV quantum sensors in diamond nanopillar arrays. The
pillars improve light collection efficiency by guiding excitation/emission
light, which improves sensitivity. More importantly, they also improve the size
of the signal at the NV by removing screening charges as well as coordinating
the neuron growth to the tips of the pillars where the NV is located. Here, we
provide a growth study to demonstrate coordinated neuron growth as well as the
first simulation of nano-scopic neuron electric and magnetic fields to assess
the enhancement provided by the nanopillar geometry.Comment: 18 pages including supplementary and references, 12 figure
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