19 research outputs found
Entrenamiento de fuerza en niños y diabetes
Revisión bibliogråfica sobre el entrenamiento de fuerza en niños y los cambios provocados en el cuerpo a nivel hormonal o metabólico, y asà encontrar un método de prevención o tratamiento para la diabetes desde edades tempranas
BOTĂNICA E FISIOLOGIA/ BOTANY AND PHYSIOLOGY ANTIOXIDANT ACTIVITY AND PHYSICOCHEMICAL PARAMETERS IN âCUERNAVAQUEĂAâ MEXICAN PLUM (Spondias purpurea L.) AT DIFFERENT RIPENING STAGES
31 visiones actuales de la transparencia
Treinta y una aportaciones de autores nacionales y extranjeros sobre la transparencia de las instituciones pĂșblicas y de los sujetos obligados por la Ley 19/2013 de 9 de diciembre y el derecho de acceso a la informaciĂłn pĂșblica
Jardins per a la salut
Facultat de FarmĂ cia, Universitat de Barcelona. Ensenyament: Grau de FarmĂ cia. Assignatura: BotĂ nica farmacĂšutica. Curs: 2014-2015. Coordinadors: Joan Simon, CĂšsar BlanchĂ© i Maria Bosch.Els materials que aquĂ es presenten sĂłn el recull de les fitxes botĂ niques de 128 espĂšcies presents en el JardĂ Ferran Soldevila de lâEdifici HistĂČric de la UB. Els treballs han estat realitzats manera individual per part dels estudiants dels grups M-3 i T-1 de lâassignatura BotĂ nica FarmacĂšutica durant els mesos de febrer a maig del curs 2014-15 com a resultat final del Projecte dâInnovaciĂł Docent «Jardins per a la salut: aprenentatge servei a BotĂ nica farmacĂšutica» (codi 2014PID-UB/054). Tots els treballs sâhan dut a terme a travĂ©s de la plataforma de GoogleDocs i han estat tutoritzats pels professors de lâassignatura. Lâobjectiu principal de lâactivitat ha estat fomentar lâaprenentatge autĂČnom i col·laboratiu en BotĂ nica farmacĂšutica. TambĂ© sâha pretĂšs motivar els estudiants a travĂ©s del retorn de part del seu esforç a la societat a travĂ©s dâuna experiĂšncia dâAprenentatge-Servei, deixant disponible finalment el treball dels estudiants per a poder ser consultable a travĂ©s dâuna Web pĂșblica amb la possibilitat de poder-ho fer in-situ en el propi jardĂ mitjançant codis QR amb un smartphone
New Liquid Source of Antioxidant Phenolic Compounds in the Olive Oil Industry: Alperujo Water
14 PĂĄginas.-- 3 Figuras.-- 4 TablasThe current management of alperujo as the main solid by-product from the two-phase olive oil extraction system has led to the appearance of a new liquid effluent that until now was treated together with the alperujo itself. The composition and antioxidant properties of its bioactive components at different depths of the pond were studied using colorimetric and HPLC with UV and MS detectors, DPPH, reducing power and rancimat. The concentration of suspended solids varied between 1.71 and 8.49 g/L, total fat was between 0.74 and 1.47 g/L, and total phenols were found between 3.74 and 4.11 g/L, which included hydroxytyrosol, 3,4-dihydroxyphenylglycol and tyrosol as the main phenols. Two types of extracts were obtained through two industrial systems with ethyl acetate and by chromotography, with an average content in total sugars of 2.1% and 3.16%, total phenols of 17.9% and 28.6% and hydroxytyrosol of 51.5 and 79.0 mg/g of extract, respectively. The activity presented by the chromatographic extract was higher in terms of free radical sequestering capacity, reducing power and the inhibition of lipid oxidation. Obtaining bioactive extracts would improve the formulation of food with natural components and at the same time would be the first step in a biorefinery to improve the management of the new effluent.This research was supported by the Spanish Ministry of Economy and Competitiveness and co-funded by a European Social Fund (ESF) (project AGL2016-79088R), the Spanish Ministry of Economy and Competitiveness Ramon y Cajal Programme: (RyC 2012-10456).Peer reviewe
Clinical factors associated with discontinuation of ts/ bDMARDs in rheumatic patients from the BIOBADASER III registry
Rheumatoid arthritis; Spondyloarthritis; Ankylosing spondylitis; Psoriatic arthritisArtritis reumatoide; Espondiloartritis; Espondilitis anquilosante; Artritis psoriĂĄsicaArtritis reumatoide; Espondiloartritis; Espondiliti anquilosant; Artritis psoriĂ sicaBiologic and targeted synthetic disease-modifying antirheumatic drugs (ts/bDMARDs) play a pivotal role in the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). Persistence of therapy provides an index of a drugâs overall effectiveness. The objective of the study was to identify factors associated with discontinuation of ts/bDMARDs in a real-world dataset. The study population comprised patients diagnosed with RA, PsA, and AS included in the BIOBADASER registry for whom follow-up data were available until November 2019. Patient features and treatment data were included in the analysis. The KaplanâMeier method was used to study
survival of the different drugs according to the reason for discontinuation. Factors associated with discontinuation were studied using Cox regression models and bivariate and multivariate analyses. P values of less than 0.05 were regarded as statistically significant. The study population comprised 4,752 patients who received a total of 8,377 drugs, of which 4,411 (52.65%) were discontinued. The KaplanâMeier curves showed that survival for first-line treatment was greater in all 3 groups (p < 0.001). Patients with RA had a greater risk of discontinuation if they were younger (HR, 0.99; 95% CI 0.99â1.00), if they were receiving anti-TNFα agents (HR, 0.61; 95% CI 0.54â0.70), and if they
had more comorbid conditions (HR, 1.09; 95% CI 1.00â1.17). Patients with PsA had a higher risk if they were women (HR, 1.36; 95% CI 1.15â1.62) and if they were receiving other ts/bDMARDs (HR, 1.29; 95% CI 1.05â1.59). In patients with AS, risk increased with age (HR, 1.01; 95% CI 1.00â1.02), as did the number of comorbid conditions (HR, 1.27; 95% CI 1.12â1.45). The factors that most affected discontinuation of ts/bDMARDs were line of treatment, age, type of drug, sex, comorbidity and the year of initiation of treatment. The association with these factors differed with each disease, except for first-line treatment, which was associated with a lower risk of discontinuation in all 3 diseases
New Liquid Source of Antioxidant Phenolic Compounds in the Olive Oil Industry: Alperujo Water
The current management of alperujo as the main solid by-product from the two-phase olive oil extraction system has led to the appearance of a new liquid effluent that until now was treated together with the alperujo itself. The composition and antioxidant properties of its bioactive components at different depths of the pond were studied using colorimetric and HPLC with UV and MS detectors, DPPH, reducing power and rancimat. The concentration of suspended solids varied between 1.71 and 8.49 g/L, total fat was between 0.74 and 1.47 g/L, and total phenols were found between 3.74 and 4.11 g/L, which included hydroxytyrosol, 3,4-dihydroxyphenylglycol and tyrosol as the main phenols. Two types of extracts were obtained through two industrial systems with ethyl acetate and by chromotography, with an average content in total sugars of 2.1% and 3.16%, total phenols of 17.9% and 28.6% and hydroxytyrosol of 51.5 and 79.0 mg/g of extract, respectively. The activity presented by the chromatographic extract was higher in terms of free radical sequestering capacity, reducing power and the inhibition of lipid oxidation. Obtaining bioactive extracts would improve the formulation of food with natural components and at the same time would be the first step in a biorefinery to improve the management of the new effluent
Bayesian Analysis of the Effects of Olive Oil-Derived Antioxidants on Cryopreserved Buck Sperm Parameters
The present study evaluates the effect of olive oil-derived antioxidants, hydroxytyrosol (HT) and 3,4-dihydroxyphenylglycol (DHPG), on cryopreserved caprine sperm using Bayesian inference of ANOVA. For this proposal, sperm was collected, pooled and diluted in freezing media supplemented with different concentrations of HT, DHPG and the mixture (MIX) of both antioxidants. Sperm motility, viability, acrosome integrity, mitochondrial status, and lipid peroxidation (LPO) were assessed in fresh and frozen-thawed sperm samples. The results provided evidence that HT at low concentrations improves sperm motility and viability, and reduces the LPO. Contrastingly, DHPG and MIX exert a positive effect by reducing LPO values as concentration increases. Additionally, mitochondrial potential was reduced when samples were supplemented with HT at low concentrations and mixture of both antioxidants. Conclusively, the addition of olive oil-derived antioxidants (HT at 10 ”g/mL and DHPG at 30 ”g/mL) implements a protective effect in cryopreserved buck sperm. Bayesian analysis alternatives offer new possibilities to determine the repercussion of antioxidants on sperm, both quantitatively and qualitatively