Numerical simulation of liquid sloshing in a partially filled container with inclusion of compressibility effects

A numerical scheme of study is developed to model compressible two-fluid flows simulating liquid sloshing in a partially filled tank. For a two-fluid system separated by an interface as in the case of sloshing, not only a Mach-uniform scheme is required, but also an effective way to eliminate unphysical numerical oscillations near the interface. By introducing a preconditioner, the governing equations expressed in terms of primitive variables are solved for both fluids (i.e. water, air, gas etc.) in a unified manner. In order to keep the interface sharp and to eliminate unphysical numerical oscillations in unsteady fluid flows, the non-conservative implicit Split Coefficient Matrix Method (SCMM) is modified to construct a flux difference splitting scheme in the dual time formulation. The proposed numerical model is evaluated by comparisons between numerical results and measured data for sloshing in an 80% filled rectangular tank excited at resonance frequency. Through similar comparisons, the investigation is further extended by examining sloshing flows excited by forced sway motions in two different rectangular tanks with 20% and 83% filling ratios. These examples demonstrate that the proposed method is suitable to capture induced free surface waves and to evaluate sloshing pressure loads acting on the tank walls and ceiling

Experimental investigation of shock-cell noise reduction for dual-stream nozzles in simulated flight comprehensive data report. Volume 1: Test nozzles and acoustic data

Parameters which contribute to supersonic jet shock noise were investigated for the purpose of determining means to reduce such noise generation to acceptable levels. Six dual-stream test nozzles with varying flow passage and plug closure designs were evaluated under simulated flight conditions in an anechoic chamber. All nozzles had combined convergent-divergent or convergent flow passages. Acoustic behavior as a function of nozzle flow passage geometry was measured. The acoustic data consist primarily of 1/3 octave band sound pressure levels and overall sound pressure levels. Detailed schematics and geometric characteristics of the six scale model nozzle configurations and acoustic test point definitions are presented. Tabulation of aerodynamic test conditions and a computer listing of the measured acoustic data are displayed

Evidence for a circumplanetary disk around protoplanet PDS 70 b

We present the first observational evidence for a circumplanetary disk around the protoplanet PDS~70~b, based on a new spectrum in the $K$ band acquired with VLT/SINFONI. We tested three hypotheses to explain the spectrum: Atmospheric emission from the planet with either (1) a single value of extinction or (2) variable extinction, and (3) a combined atmospheric and circumplanetary disk model. Goodness-of-fit indicators favour the third option, suggesting circumplanetary material contributing excess thermal emission --- most prominent at $\lambda \gtrsim 2.3 \mu$m. Inferred accretion rates ($\sim 10^{-7.8}$--$10^{-7.3} M_J$ yr$^{-1}$) are compatible with observational constraints based on the H$\alpha$ and Br$\gamma$ lines. For the planet, we derive an effective temperature of 1500--1600 K, surface gravity $\log(g)\sim 4.0$, radius $\sim 1.6 R_J$, mass $\sim 10 M_J$, and possible thick clouds. Models with variable extinction lead to slightly worse fits. However, the amplitude ($\Delta A_V \gtrsim 3$mag) and timescale of variation ($\lesssim$~years) required for the extinction would also suggest circumplanetary material.Comment: 8 pages, 2 figures, 1 table. This is a pre-copyedited, author-produced PDF of an article accepted for publication in ApJL on 2019 May 1

Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria.

Dihydroartemisinin-piperaquine (DP) could become a leading fixed combination malaria treatment worldwide. Although there is accumulating evidence of efficacy and safety from clinical trials, data on cardiotoxicity are limited. In two randomized controlled trials in Thailand, 56 patients had ECGs performed before treatment, 4 hours after the first dose, and 4 hours after the last dose. The mean (95% CI) changes in QTc interval (Bazett's correction) were 2 (-6 to 9) ms and 14 (7 to 21) ms, respectively. These small changes on the third day of treatment are similar to those observed elsewhere in the convalescent phase following antimalarial treatment with drugs known to have no cardiac effects and are therefore likely to result from recovery from acute malaria and not the treatment given. At therapeutic doses, DP does not have clinically significant effects on the electrocardiogram

Understanding initial data for black hole collisions

Numerical relativity, applied to collisions of black holes, starts with initial data for black holes already in each other's strong field. The initial hypersurface data typically used for computation is based on mathematical simplifying prescriptions, such as conformal flatness of the 3-geometry and longitudinality of the extrinsic curvature. In the case of head on collisions of equal mass holes, there is evidence that such prescriptions work reasonably well, but it is not clear why, or whether this success is more generally valid. Here we study these questions by considering the ``particle limit'' for head on collisions of nonspinning holes. Einstein's equations are linearized in the mass of the small hole, and described by a single gauge invariant spacetime function psi, for each multipole. The resulting equations have been solved by numerical evolution for collisions starting from various initial separations, and the evolution is studied on a sequence of hypersurfaces. In particular, we extract hypersurface data, that is psi and its time derivative, on surfaces of constant background Schwarzschild time. These evolved data can then be compared with ``prescribed'' data, evolved data can be replaced by prescribed data on any hypersurface, and evolved further forward in time, a gauge invariant measure of deviation from conformal flatness can be evaluated, etc. The main findings of this study are: (i) For holes of unequal mass the use of prescribed data on late hypersurfaces is not successful. (ii) The failure is likely due to the inability of the prescribed data to represent the near field of the smaller hole. (iii) The discrepancy in the extrinsic curvature is more important than in the 3-geometry. (iv) The use of the more general conformally flat longitudinal data does not notably improve this picture.Comment: 20 pages, REVTEX, 26 PS figures include

Free-jet feasibility study of a thermal acoustic shield concept for AST/VCE application-dual stream nozzles. Comprehensive data report. Volume 2: Laser velocimeter and suppressor. Base pressure data

Acoustic and diagnostic data that were obtained to determine the influence of selected geometric and aerodynamic flow variables of coannular nozzles with thermal acoustic shields are summarized in this comprehensive data report. A total of 136 static and simulated flight acoustic test points were conducted with 9 scale-model nozzles. Aerodynamic laser velocimeter measurements were made for four selected plumes. In addition, static pressure data in the chute base region of the suppressor configurations were obtained to assess the influence of the shield stream on the suppressor base drag

Evolving the Bowen-York initial data for spinning black holes

The Bowen-York initial value data typically used in numerical relativity to represent spinning black hole are not those of a constant-time slice of the Kerr spacetime. If Bowen-York initial data are used for each black hole in a collision, the emitted radiation will be partially due to the ``relaxation'' of the individual holes to Kerr form. We compute this radiation by treating the geometry for a single hole as a perturbation of a Schwarzschild black hole, and by using second order perturbation theory. We discuss the extent to which Bowen-York data can be expected accurately to represent Kerr holes.Comment: 10 pages, RevTeX, 4 figures included with psfi

Colliding black holes: how far can the close approximation go?

We study the head-on collision of two equal-mass momentarily stationary black holes, using black hole perturbation theory up to second order. Compared to first-order results, this significantly improves agreement with numerically computed waveforms and energy. Much more important, second-order results correctly indicate the range of validity of perturbation theory. This use of second-order, to provide ``error bars,'' makes perturbation theory a viable tool for providing benchmarks for numerical relativity in more generic collisions and, in some range of collision parameters, for supplying waveform templates for gravitational wave detection.Comment: 6 pages, RevTeX, 2 figures included with eps

Analysis of variation in distance, number, and distribution of spotting in southeast Australian wildfires

Spotting during wildfires can significantly influence the way wildfires spread and reduce the chances of successful containment by fire crews. However, there is little published empirical evidence of the phenomenon. In this study, we have analysed spotting patterns observed from 251 wildfires from a database of over 8000 aerial line scan images capturing active wildfire across mainland southeast Australia between 2002 and 2018. The images were used to measure spot fire numbers, number of “long-distance” spot fires (> 500 m), and maximum spotting distance. We describe three types of spotting distance distributions, compare patterns among different regions of southeast Australia, and associate these with broad measures of rainfall, elevation, and fuel type. We found a relatively high correlation between spotting distance and numbers; however, there were also several cases of wildfires with low spot fire numbers producing very long-distance spot fires. Most long-distance spotting was associated with a “multi-modal” distribution type, where high numbers of spot fires ignite close to the source fire and isolated or small clumps of spot fires ignite at longer distances. The multi-modal distribution suggests that current models of spotting distance, which typically follow an exponential-shaped distribution, could underestimate long-distance spotting. We also found considerable regional variation in spotting phenomena that may be associated with significant variation in rainfall, topographic ruggedness, and fuel descriptors. East Victoria was the most spot-fire-prone of the regions, particularly in terms of long-distance spotting

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

This is the final version. It was first published by Wiley in The Journal of Physiology at http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.275263/abstract.Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species (ROS) generation, but at the cost of impaired electron transport chain (ETC) activity. Dietary nitrate supplementation improves mitochondrial efficiency and can promote tissue oxygenation by enhancing blood flow. We therefore hypothesised that ETC dysfunction, impaired energetics and oxidative damage in the hearts of rats exposed to chronic hypoxia could be alleviated by sustained administration of a moderate dose of dietary nitrate. Male Wistar rats (n=40) were given water supplemented with 0.7 mmol/L NaCl (as control) or 0.7 mmol/L NaNO3, elevating plasma nitrate levels by 80%, and were exposed to 13% O2 (hypoxia) or normoxia (n=10 per group) for 14 days. Respiration rates, ETC protein levels, mitochondrial density, ATP content and protein carbonylation were measured in cardiac muscle. Complex I respiration rates and protein levels were 33% lower in hypoxic/NaCl rats compared with normoxic/NaCl controls. Protein carbonylation was 65% higher in hearts of hypoxic rats compared with controls, indicating increased oxidative stress, whilst ATP levels were 62% lower. Respiration rates, complex I protein and activity, protein carbonylation and ATP levels were all fully protected in the hearts of nitrate-supplemented hypoxic rats. Both in normoxia and hypoxia, dietary nitrate suppressed cardiac arginase expression and activity and markedly elevated cardiac L-arginine concentrations, unmasking a novel mechanism of action by which nitrate enhances tissue NO bioavailability. Dietary nitrate therefore alleviates metabolic abnormalities in the hypoxic heart, improving myocardial energetics