Polyphosphazenes for the Stille reaction: A new type of recyclable stannyl reagents

Producción CientíficaThe random phosphazene copolymer {[N=P((CH2)7-Br)Ph]0,5[N=PMePh]0,5}n (2) and the block copolyphosphazene {[N=P((CH2)7-Br)Ph]25[N=PMePh]20}-b-[N=P(O2C12H8)]55 (5), having a branch with two randomly distributed units, have been synthesized and used as precursors for the stannyl derivatives {[N=P((CH2)7-SnBu2An)Ph]0,5[N=PMePh]0,5}n (3) and {[N=P((CH2)7-SnBu2An)Ph]25[N=PMePh]20}-b-[N=P(O2C12H8)]55 (6, An = p-MeOC6H4). Polymers 3 and 6 were tested as recyclable tin reagents in the Stille cross-coupling reaction with C6H5I, using various Pd catalysts and different experimental conditions. Polymer 6 can be recycled without significant release of tin, but its efficiency decreased after three consecutive cycles. This effect was explained by studying the self-assembly of the polymer under the same conditions used for the catalytic experiments, which evidenced the progressive coalescence of the polymeric vesicles (polymersomes) leading to stable and bigger core-shell aggregates by the attraction of the [N=P(O2C12H8)] rich membranes, thus decreasing the accessibility of the tin active centers.2017-12-15Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA302U13)Ministerio de Economía, Industria y Competitividad (CTQ2014-56345)Ministerio de Economía, Industria y Competitividad (CTQ2013-48406-P)Universidad de Oviedo (Project UNOV-13-EMERG-GIJON-08

Baby-led weaning: Health professionals ‘knowledge and attitudes and parents’ experiences from Spain. A mixed methods approach

[EN] Baby-led weaning or self-regulated small chunk feeding by the baby has emerged as an alternative to the traditional method of complementary feeding. Parents and healthcare professionals often differ in the benefits and drawbacks about it. The research aims were to describe the knowledge of health professionals about complementary feeding and baby-led weaning (BLW) method and the attitudes towards its recommendation, and to explore the knowledge, experiences and attitudes of parents who have used this method to feed their children. A mixed methods research was carried out. A questionnaire was completed by 38 health professionals and 10 interviews were conducted with participating mothers. A total of 52.6% of health professionals recommended initiating complementary feeding at 6 months of age, a guideline followed by the mothers who used BLW. Some 86.8% of the professionals knew the BLW method and 76.3% knew its benefits, but the mothers consulted mainly informal sources of information sources to learn about and implement it. The health professionals stated that it facilitated family transition, enabled the infant to adapt better to flavours and textures, promoted chewing and the development of fine motor skills, improved growth and might also be a protective factor against obesity. The mothers noted that the method was natural, encouraged infant autonomy and promoted healthy eating habits. The health professionals expressed varied opinions concerning the risks entailed in the method. The main conclusions are that the majority of health professionals participating in the study know the BLW method, its benefits; however, they do not recommend it in all cases. Mothers listen to the advice of professionals but continue to rely on other informal sources of information.S

Caracterización de la fauna de macroinvertebrados bentónicos en la cuenca del Río Orbigo (león)

P. 195-202Se analizan las asociaciones de macroinvertebrados en relación con las variaciones físicoquimicas y geomorfológicas de la cuenca. En 1os resultados obtenidos del Analisis en Componentes Principales el primer eje diferencia los rios temporalesN

Prevalence and Mode of Birth in Late Fetal Mortality in Spain, 2016–2019

Background: The rate of cesarean sections in late fetal mortality remains high. We aimed to determine the prevalence of late fetal mortality in Spain and risk factors for cesarean birth in women with stillbirth ≥ 28 weeks gestation between 2016–2019. (2) Methods: A retrospective observational study with national data between 2016–2019. A total of 3504 births with fetal dead were included. Sociodemographic, obstetrical and neonatal variables were analyzed using univariate and multivariate logistic regression (MLR), with cesarean birth with a stillborn ≥ 28 weeks gestation as the dependent variable. (3) Results: The late fetal mortality rate was 2.8 × 1000; 22.7% of births were by cesarean section. Factors associated with cesarean were having a multiple birth (aOR 6.78); stillbirth weight (aOR 2.41); birth taking place in towns with over 50,000 inhabitants (aOR 1.34); and mother’s age ≥ 35 (aOR 1.23). (4) Conclusions: The late fetal mortality rate increased during the period. The performance of cesarean sections was associated with the mother’s age, obstetric factors and place of birth. Our findings encourage reflection on how to best put into practice national clinical and socio-educational prevention strategies, as well as the approved protocols on how childbirth should be correctly conducted

Factors Associated with Postpartum Sexual Dysfunction in Spanish Women: A Cross-Sectional Study

(1) Background: Female sexual dysfunction (FSD) has a high prevalence globally, and perinatal factors favor FSD, especially in the postpartum period. The aim was to determine the prevalence and factors influencing FSD in the postpartum period; (2) Methods: An observational study carried out in three primary care centers in southern Spain, with women in the postpartum period who had a single low-risk birth. One hundred and seventeen women answered the Female Sexual Function questionnaire during the 4th month postpartum, between January 2020 and December 2021. Sociodemographic, obstetric, neonatal variables and level of self-esteem were analyzed. A multiple logistic regression model was carried out; (3) Results: 78.4% had high level of self-esteem. FSD prevalence was 89.7%. Factors related to FSD were having an instrumental vaginal delivery, women with university studies, and prenatal preparation. Maternal age ≥ 35, multiparity, pathological processes in the child, a medium–low level of self-esteem and newborn weight were associated with disorders in some of domains of sexual function; (4) Conclusions: FSD is highly prevalent in the postpartum period and is associated with preventable factors. A preventive approach by health professionals to these factors is essential. Health services should implement postpartum follow-up programs, which may coincide in time and place with newborn follow-up programs

Cannabis use network and its relationship to stress in adolescent students

[ES] La adolescencia es un periodo de cambios asociados a un incremento del estrés, y una etapa de especial vulnerabilidad para el inicio de consumo de cannabis. Debido a que en esta etapa adquieren mayor importancia las relaciones entre iguales, ¿existe relación entre las redes, el consumo y el estrés?[EN] Adolescence is a period of change associated with increased stress, and a particularly vulnerable time for the initiation of cannabis use. As peer relationships become more important at this stage, is there a relationship between networks, cannabis use and stress

Preocupaciones prenatales en el primer trimestre de embarazo en la mujer de la comarca del Bierzo

[ES] A lo largo del período de gestación, es común que las mujeres enfrenten diversas inquietudes vinculadas al bienestar del bebé, el proceso del parto y el rol de ser madre. Estas inquietudes que surgen durante el embarazo son perfectamente normales y frecuentes, dado que esta etapa representa una transición en la vida que conlleva notables transformaciones físicas, emocionales y socialesS