Role of Environment Dimensions to strive Sustainable Entrepreneurship: A Triple Bottom Line Approach

Purpose: The study aims to examine the role of Sustainable Entrepreneurship through the lens of Triple Bottom Line (TBL) with intervention of environment dimensions in Indian MSMEs context.   Theoretical framework: Sustainability has become the most important concern in today’s world due to the changes in the climate and environment deterioration. The TBL approach includes the people, planet and profit perspective; environment dimensions include the green and non-green initiatives that would help entrepreneurs to achieve their sustainable goals.   Design/methodology/approach: The quantitative research design is adopted to collect 107 entrepreneurs’ data from Delhi NCR using purposive sampling. The study examines the relationship among Sustainable Entrepreneurs (profit, planet and people) and environmental dimensions (green and non-green initiative) using SPSS and Hayes PROCESS.   Findings: The study concludes that there exists a correlation between people and planet; people and non-green initiatives; planet and profit; planet and non-green initiatives; and lastly green initiatives and non-green initiatives. In addition, non-green initiative mediates the relationship between people and planet. However, planet is correlated with only profit.   Research, Practical & Social implications: The research discusses various approaches for MSME to endeavour sustainability with the help of environment dimensions. The appropriate practice of adopting such sustainable approaches will eventually drive enterprises towards profit, thus becoming sustainable entrepreneurs.   Originality/value: TBL approach is viewed along with the environmental dimensions for the purpose of protecting environment and enabling an enterprise move towards higher profit. The study also discusses strategies for policymakers, education institutes for promoting sustainable entrepreneurship.

Wireless Body Area Networks for Health-Care Systems

Body Area Network (BAN) development has been driven by pressure to reduce health care costs and by an increased focus on prevention and early risk BANs are highly localized wireless networks that can potentially support a variety of medical applications. Our final paper deals with all aspects involved in Wireless BAN (WBAN) in health care arena

Study of Electron Transport in Semiconductor Materials

The Monte Carlo Simulation Technique is described and the technique has been applied to obtain the velocity-field characteristics of different compound semiconductors. The results agree with the available experimental data and with those obtained by Boltzmann Transport Equation analytically

Skyrmions and magnetic bubbles in spin-orbit coupled metallic magnets

Motivated by the observation of Skyrmion-like magnetic textures in 2D itinerant ferromagnets Fe$_n$GeTe$_2$ ($n \geq3$), we develop a microscopic model combining itinerant magnetism and spin-orbit coupling on a triangular lattice. The ground state of the model in the absence of magnetic field consists of filamentary magnetic domain walls revealing a striking similarity with our magnetic force microscopy experiments on Fe$_3$GeTe$_2$. In the presence of magnetic field, these filaments were found to break into large size magnetic bubbles in our experiments. We identify uniaxial magnetic anisotropy as an important parameter in the model that interpolates between magnetic Skyrmions and ferromagnetic bubbles. Consequently, our work uncovers new topological magnetic textures that merge properties of Skyrmions and ferromagnetic bubbles

Odgovor na stres u pasa pod epiduralnom anestezijom deksmedetomidinom uz primjenu lokalnih anestetika ili bez njih i premedikaciju atropin-midazolamom

The aim of our study was to evaluate stress response in atropine-midazolam premedicated dogs under epidural dexmedetomidine alone or with local anaesthetics. A total of 24 healthy, client-owned mixed breed adult dogs, with an average weight of 18.1 ± 2.4 kg were allotted randomly (n = 6) to four groups, viz: A, B, C and D. All the animals were premedicated intramuscularly with atropine (0.04 mg/kg) and after 5 minutes by intravenous midazolam (0.7 mg/kg). After 10 minutes of premedication, in group A dexmedetomidine (7 μg/kg) and in groups B, C and D, in addition to dexmedetomidine (7 μg/kg), lidocaine (4.4 mg/kg), bupivacaine (2 mg/kg) and ropivacaine (2 mg/kg) were administered, respectively, at the lumbosacral epidural space. Anaesthesia was maintained with 1 per cent propofol as and when needed. Stress response during the surgical procedure was evaluated and assessed by measuring plasma levels of insulin, glucose, cortisol and blood neutrophil count at 0 min, 30 min and 90 min after epidural administration of the drugs in all groups. Insulin fluctuated non-significantly around the baseline in all groups, except for a very significant decrease at 30 min in group C, and a significant increase at the same interval in group B. Glucose values significantly increased in group D at 90 min. Cortisol showed a non-significant decrease from base values in all groups, except for a significant increase at 90 min in group A. The neutrophil count varied non-significantly at all intervals in all groups. No significant differences were recorded in glucose, cortisol and neutrophil count between the different groups at different intervals. It was concluded that dexmedetomidine, in combination with lidocaine, bupivacaine or ropivacaine, at the doses studied may be employed safely for epidural anaesthesia and analgesia, with adequate blunting of stress response during surgical procedures.Cilj istraživanja bio je procijeniti odgovor na stres u pasa pod epiduralnom anestezijom deksmedetomidinom, uz primjenu lokalnih anestetika ili bez njih, kojima je kao premedikacija dan atropin-midazolam. Uključena su 24 zdrava odrasla psa mješanca, u vlasništvu klijenata. Prosječna tjelesna masa pasa iznosila je 18,1 ± 2,4 kg. Metodom slučajnog izbora psi su podijeljeni u četiri skupine iste veličine (n = 6) s oznakama A, B, C i D. Sve su životinje za premedikaciju intramuskularno dobile atropin (0,04 mg/kg) i nakon pet minuta intravenski midazolam (0,7 mg/kg). Deset minuta poslije premedikacije svim je skupinama u lumbosakralni epiduralni prostor dan deksmedetomidin (7 μg/kg), s tim da je skupini B dodan i lidokain (4,4 mg/kg), skupini C bupivakain (2 mg/kg), a skupini D ropivakain (2 mg/kg). Anestezija je održavana 1 %-tnim propofolom prema potrebi. Odgovor na stres za vrijeme kirurškog zahvata ustanovljen je mjerenjem razina inzulina, glukoze, kortizola u plazmi i broja neutrofila u krvi. Navedeni pokazatelji mjereni su 0 minuta, 30 minuta i 90 minuta nakon epiduralne primjene lijekova u svim skupinama. Vrijednosti inzulina nisu pokazale veću promjenjivost, osim statistički visoko značajnog smanjenja u skupini C nakon 30 minuta i statistički značajnog povećanja u skupini B u istom intervalu. Kod pasa iz skupine D razina glukoze značajno je porasla u 90. minuti. Smanjenje razina kortizola u svim skupinama nije bilo značajno, a u skupini A opažen je značajni porast ovog pokazatelja 90 minuta nakon primjene lijekova. Broj neutrofila nije značajnije varirao ni u jednoj skupini i ni u jednom intervalu mjerenja. Nije bilo značajnih razlika u razinama glukoze i kortizola te broju neutrofila među skupinama u različiitm intervalima. Zaključeno je da se sa svrhom smanjenja stresa pri kirurškim zahvatima za epiduralnu anesteziju i analgeziju sigurno može rabiti deksmedetomidin u kombinaciji s istraženim dozama lidokaina, bupivakaina ili ropivakaina

Integrated view and comparative analysis of baseline protein expression in mouse and rat tissues

The increasingly large amount of proteomics data in the public domain enables, among other applications, the combined analyses of datasets to create comparative protein expression maps covering different organisms and different biological conditions. Here we have reanalysed public proteomics datasets from mouse and rat tissues (14 and 9 datasets, respectively), to assess baseline protein abundance. Overall, the aggregated dataset contained 23 individual datasets, including a total of 211 samples coming from 34 different tissues across 14 organs, comprising 9 mouse and 3 rat strains, respectively. In all cases, we studied the distribution of canonical proteins between the different organs. The number of canonical proteins per dataset ranged from 273 (tendon) and 9,715 (liver) in mouse, and from 101 (tendon) and 6,130 (kidney) in rat. Then, we studied how protein abundances compared across different datasets and organs for both species. As a key point we carried out a comparative analysis of protein expression between mouse, rat and human tissues. We observed a high level of correlation of protein expression among orthologs between all three species in brain, kidney, heart and liver samples, whereas the correlation of protein expression was generally slightly lower between organs within the same species. Protein expression results have been integrated into the resource Expression Atlas for widespread dissemination

Expression Atlas update: gene and protein expression in multiple species.

The EMBL-EBI Expression Atlas is an added value knowledge base that enables researchers to answer the question of where (tissue, organism part, developmental stage, cell type) and under which conditions (disease, treatment, gender, etc) a gene or protein of interest is expressed. Expression Atlas brings together data from >4500 expression studies from >65 different species, across different conditions and tissues. It makes these data freely available in an easy to visualise form, after expert curation to accurately represent the intended experimental design, re-analysed via standardised pipelines that rely on open-source community developed tools. Each study's metadata are annotated using ontologies. The data are re-analyzed with the aim of reproducing the original conclusions of the underlying experiments. Expression Atlas is currently divided into Bulk Expression Atlas and Single Cell Expression Atlas. Expression Atlas contains data from differential studies (microarray and bulk RNA-Seq) and baseline studies (bulk RNA-Seq and proteomics), whereas Single Cell Expression Atlas is currently dedicated to Single Cell RNA-Sequencing (scRNA-Seq) studies. The resource has been in continuous development since 2009 and it is available at https://www.ebi.ac.uk/gxa