Biaix de gènere als fons de l'Arxiu Municipal de Barcelona: Anàlisi i proposta de millora

El treball analitza els productors i productores dels fons personals i la temàtica dels fons d'entitats conservats a l'Arxiu Municipal de Barcelona amb l'objectiu de detectar si s'estan donant biaixos de gènere a l'AMB a l'hora d'adquirir documentació privada. Els resultats demostren que del total de fons personals custodiats a l'AMB, només el 13% són produïts per dones, així com que no es conserva cap fons d'associacions relacionat amb la lluita feminista, les dones o el col·lectiu LGTBI. En segon lloc, s'estudien les polítiques de gènere i LGTBI de l'Ajuntament de Barcelona i el grau d'aplicació d'aquestes als arxius de l'AMB.En primer lugar, el trabajo analiza la producción de los fondos personales y la temática de los fondos de entidades conservados en el Archivo Municipal de Barcelona (AMB) con el objetivo de detectar si se está dando un sesgo de género en el AMB a la hora de adquirir documentación privada. Los resultados demuestran que, del total de fondos personales custodiados en él, solo el 13% son producidos por mujeres, así como que no se conserva ningún fondo de asociaciones relacionado con la lucha feminista, las mujeres o el colectivo LGTBI. En segundo lugar, se estudian las políticas de género y LGTBI del Ayuntamiento de Barcelona y el grado de aplicación de estas en el AMB.This academic work analyzes the production of personal funds and the thematic of the entities funds preserved in the Arxiu Municipal de Barcelona (AMB). The main objective is to detect if there is a gender bias in the AMB when acquiring private documentation. The results show that from the total funds only 13% of the funds kept in the AMB are produced by women; as well as any entity fund related with women's movement or the LGTBI collective is preserved in the AMB. They also show an absence of funds coming from feminist or LGTBI organizations. This paper also studies the Barcelona City Council's gender and LGTBI policies and how they are applied in the AMB

Reduced serial dependence suggests deficits in synaptic potentiation in anti-NMDAR encephalitis and schizophrenia

A mechanistic understanding of core cognitive processes, such as working memory, is crucial to addressing psychiatric symptoms in brain disorders. We propose a combined psychophysical and biophysical account of two symptomatologically related diseases, both linked to hypofunctional NMDARs: schizophrenia and autoimmune anti-NMDAR encephalitis. We first quantified shared working memory alterations in a delayed-response task. In both patient groups, we report a markedly reduced influence of previous stimuli on working memory contents, despite preserved memory precision. We then simulated this finding with NMDAR-dependent synaptic alterations in a microcircuit model of prefrontal cortex. Changes in cortical excitation destabilized within-trial memory maintenance and could not account for disrupted serial dependence in working memory. Rather, a quantitative fit between data and simulations supports alterations of an NMDAR-dependent memory mechanism operating on longer timescales, such as short-term potentiation

La huella de Maruja Mallo en la obra poética de Rafael Alberti

Treball de fi de grau d'Humanitats. Curs 2017-2018Director: Domingo Ródenas de MoyaEl presente trabajo pretende reivindicar a la interesantísima Maruja Mallo, haciendo hincapié en la importancia que esta tuvo en el desarrollo artístico e intelectual de dicho poeta. Además, como suplemento, el estudio incluye un breve análisis sobre la historiografía del arte y como esta ha construido un discurso histórico incompleto y sesgado, que solo ha tenido en cuenta a una mitad privilegiada de la población

La huella de Maruja Mallo en la obra poética de Rafael Alberti

Treball de fi de grau d'Humanitats. Curs 2017-2018El presente trabajo pretende reivindicar a la interesantísima Maruja Mallo, haciendo hincapié en la importancia que esta tuvo en el desarrollo artístico e intelectual de dicho poeta. Además, como suplemento, el estudio incluye un breve análisis sobre la historiografía del arte y como esta ha construido un discurso histórico incompleto y sesgado, que solo ha tenido en cuenta a una mitad privilegiada de la población

Construcció industrialitzada i innovació: treballs d'assignatura tardor 2012: Torre Agbar

2013/201

Construcció industrialitzada i innovació: treballs d'assignatura tardor 2012: Torre Agbar

2013/201

Sex-Specific Protective Effects of APOE ε2 on Cognitive Performance

Apolipoprotein E (APOE) has an important role in the multiple trajectories of cognitive aging. However, environmental variables and other genes mediate the impact of APOE on cognition. Our main objective was to analyze the effect of APOE genotype on cognition and its interactions and relationships with sex, age, lipid profile, C-reactive protein, and Brain-derived neurotrophic factor (BDNF) genotype in a sample of 648 healthy participants over 50 years of age with a comprehensive neuropsychological assessment. Our results showed that APOE ε2 carriers performed better in the Verbal Memory (p = .002) and Fluency Domains (p = .001). When we studied the effect of sex, we observed that the beneficial effect of APOE ε2 on the normalized values of these cognitive domains occurred only in females (β = 0.735; 95% confidence interval, 0.396–1.074; p = 3.167·10−5 and β = 0.568; 95% confidence interval, 0.276–0.861; p = 1.853·10−4, respectively). Similarly, the sex-specific effects of APOE ε2 were further observed on lipidic and inflammation biomarkers. In the whole sample, APOE ε2 carriers showed significantly lower levels of total cholesterol, low-density lipoprotein cholesterol, and C-reactive protein. These differences were found only among females. Furthermore, total cholesterol and low-density lipoprotein cholesterol mediated the protective effect of APOE ε2 on cognition in the whole sample and total cholesterol in females, providing candidate physiological mechanisms for the observed genetic effects. Our results show that the neuroprotective role of APOE ε2 in cognition varies with sex and that the lipidic profile partially mediates this protection. Age-related cognitive and functional decline is a continuous biological process with different cognitive trajectories (1). Complex interactions between heritability, environmental influence, and cognitive functions in aging have been highlighted (2). In particular, genetic differences explain around 15%–25% of the variance in life expectancy (3). Therefore, the identification of susceptibility genes and their biological effects on cognitive aging is required to establish interindividual differences in this process and promote early personalized interventions to delay cognitive decline and minimize the financial burden of aging in the health care system.This work was supported by the grants 2009FI_B00285 to J.M. from the Generalitat of Catalonia, AP2006-00311 to J.J.S.-R. from the Ministerio de Ciencia y Educación, the Regional Government of Navarre to J.L.-O., FIS PI-070393 to J.F.A. from the Ministerio de Ciencia de Innovación, and from SEJ2006-15399/PSIC and the ICREA Academia program to M.M

Episodic memory and executive functions in cognitively healthy individuals display distinct neuroanatomical correlates which are differentially modulated by aging

The neuroanatomical bases of episodic memory (EM) and executive functions (EFs) have been widely addressed in patients with brain damage and in individuals with neurologic disorders. These studies reported that larger brain structures support better outcomes in both cognitive domains, thereby supporting the "bigger is better" account. However, relatively few studies have explored the cerebral morphological properties underlying EM and EFs in cognitively healthy individuals and current findings indicate no unitary theoretical explanation for the structure-function relationship. Moreover, existing studies have typically restricted the analyses to a priori defined regions of interest. Here we conducted unbiased voxel-wise analysis of the associations between regional gray as well as white matter volumes (GMv; WMv) and performance in both cognitive domains in a sample of 463 cognitively intact individuals. We found that efficiency in EM was predicted by lower GMv in brain areas belonging to the default-mode network (DMN). By contrast, EFs performance was predicted by larger GMv in a distributed set of regions, which overlapped with the executive control network (ECN). Volume of white matter bundles supporting both cross-cortical and interhemispheric connections was positively related to processing speed. Furthermore, aging modulated the relationship between regional volumes and cognitive performance in several areas including the hippocampus and frontal cortex. Our data extend the critical role of the DMN and ECN by showing that variability in their morphological properties, and not only their activation patterns, affects EM and EFs, respectively. Moreover, our finding that aging reverts these associations supports previously advanced theories of cognitive neurodevelopment

Construcció industrialitzada i innovació: recull de treballs curs 2012-2013

2013/201

Construcció industrialitzada i innovació: recull de treballs curs 2012-2013

2013/201