25 research outputs found
Serum apelin and galectin-3 in preeclampsia in Iraq
Objective This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE). Methods Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant. Results The PE group had significantly lower apelin and higher galectin-3 levels than the control group. PE group exhibited dyslipidemia and had higher β-cell functions than the controls. Galectin-3 level correlates with insulin, glucose, and IR. High galectin-3 also is correlated positively with dyslipidemia. Conclusion In PE, there is a possible contribution of galectin-3 to the harmful effects of IR and dyslipidemia
Experience and confidence in vaginal breech and twin deliveries among obstetric trainees and new specialists in Australia and New Zealand
Safety of nifedipine in threatened preterm labor: Investigation by three-dimensional echocardiography
Antenatal Betamethasone: A Prolonged Time Interval from Administration to Delivery Is Associated with an Increased Incidence of Severe Intraventricular Hemorrhage in Infants Born before 28 Weeks Gestation
OBJECTIVE: To examine the effects of antenatal steroids on severe intraventricular hemorrhage (IVH) in infants born during the IVH vulnerable period (<28 weeks gestational age) and to evaluate rates of IVH correlated with the time interval between treatment or retreatment and birth. STUDY DESIGN: 429 infants (< 28 weeks gestation), who delivered ≥24 hours after the first BMZ course (two doses), were divided into groups based on the interval between the first course of BMZ and delivery: <10 days or ≥10 days. The primary outcome was severe IVH. Multiple regression analyses were performed to adjust for potential confounders. RESULTS: 392 infants delivered after a single BMZ course (312 delivered <10 days; 80 ≥10 days). The incidence of severe IVH was 17% for infants delivered ≥10 days and 7% for those delivered <10 days after a single BMZ course (aOR 4.16; 95% CI 1.59–10.87, p=0.004). 37 infants (born ≥10 days from the first BMZ course) received a second/rescue BMZ course. The incidence of severe IVH among infants receiving a second/rescue course was 8%, which was similar to the incidence among infants born <10 days (aOR 1.7; 95% CI 0.41–6.6, p=0.48). CONCLUSION: In infants born before 28 weeks gestation, delivery ≥10 days from the first BMZ course is associated with a higher incidence of severe IVH; a second/rescue course may reverse this effect