Computer aids and human second reading as interventions in screening mammography: two systematic reviews to compare effects on cancer detection and recall rate

Background: There are two competing methods for improving the accuracy of a radiologist interpreting screening mammograms: computer aids (CAD) or independent second reading. Methods: Bibliographic databases were searched for clinical trials. Meta-analyses estimated impacts of CAD and double reading on odds ratios for cancer detection and recall rates. Sub-group analyses considered double reading with arbitration. Results: Ten studies compared single reading with CAD to single reading. Seventeen compared double to single reading. Double reading increases cancer detection and recall rates. Double reading with arbitration increases detection rate (CI: 1.02-1.15) and decreases recall rate (CI: 0.92-0.96). CAD does not have a significant effect on cancer detection rate (CI: 0.96-1.13) and increases recall rate (95% CI: 1.09-1.12). However, there is considerable heterogeneity in the impact on recall rate in both sets of studies. Conclusion: The evidence that double reading with arbitration enhances screening is stronger than that for single reading with CAD

Evidence of photospheric vortex flows at supergranular junctions observed by FG/SOT (Hinode)

Twisting motions of different nature are observed in several layers of the solar atmosphere. Chromospheric sunspot whorls and rotation of sunspots or even higher up in the lower corona sigmoids are examples of the large scale twisted topology of many solar features. Nevertheless, their occurrence at large scale in the quiet photosphere has not been investigated. The present study reveals the existence of vortex flows located at the supergranular junctions of the quiet Sun. We use a 1-hour and a 5-hour time series of the granulation in Blue continuum and G-band images from FG/SOT to derive the photospheric flows. A feature tracking technique called Balltracking is performed to track the granules and reveal the underlying flow fields. In both time series we identify long-lasting vortex flow located at supergranular junctions. The first vortex flow lasts at least 1 hour and is ~20-arcsec-wide (~15.5 Mm). The second vortex flow lasts more than 2 hours and is ~27-arcsec-wide (~21 Mm).Comment: 4 pages, 10 figure

Post-hoc derivation of SOHO Michelson doppler imager flat fields

<p><b>Context:</b> The SOHO satellite now offers a unique perspective on the Sun as it is the only space-based instrument that can provide large, high-resolution data sets over an entire 11-year solar cycle. This unique property enables detailed studies of long-term variations in the Sun. One significant problem when looking for such changes is determining what component of any variation is due to deterioration of the instrument and what is due to the Sun itself. One of the key parameters that changes over time is the apparent sensitivity of individual pixels in the CCD array. This can change considerably as a result of optics damage, radiation damage, and aging of the sensor itself. In addition to reducing the sensitivity of the telescope over time, this damage significantly changes the uniformity of the flat field of the instrument, a property that is very hard to recalibrate in space. For procedures such as feature tracking and intensity analysis, this can cause significant errors.</p> <p><b>Aims:</b> We present a method for deriving high-precision flat fields for high-resolution MDI continuum data, using analysis of existing continuum and magnetogram data sets.</p> <p><b>Methods:</b> A flat field is constructed using a large set (1000-4000 frames) of cospatial magnetogram and continuum data. The magnetogram data is used to identify and mask out magnetically active regions on the continuum data, allowing systematic biases to be avoided. This flat field can then be used to correct individual continuum images from a similar time.</p> <p><b>Results:</b> This method allows us to reduce the residual flat field error by around a factor 6-30, depending on the area considered, enough to significantly change the results from correlation-tracking analysis. One significant advantage of this method is that it can be done retrospectively using archived data, without requiring any special satellite operations.</p&gt

Synthesising and utilising complex evidence to inform policy in education and health.

Oslo, Norway, May 19 to 21, 200

Balltracking: an highly efficient method for tracking flow fields

We present a method for tracking solar photospheric flows that is highly efficient, and demonstrate it using high resolution MDI continuum images. The method involves making a surface from the photospheric granulation data, and allowing many small floating tracers or balls to be moved around by the evolving granulation pattern. The results are tested against synthesised granulation with known flow fields and compared to the results produced by Local Correlation tracking (LCT). The results from this new method have similar accuracy to those produced by LCT. We also investigate the maximum spatial and temporal resolution of the velocity field that it is possible to extract, based on the statistical properties of the granulation data. We conclude that both methods produce results that are close to the maximum resolution possible from granulation data. The code runs very significantly faster than our similarly optimised LCT code, making real time applications on large data sets possible. The tracking method is not limited to photospheric flows, and will also work on any velocity field where there are visible moving features of known scale length