Concentration, spin and shape of dark matter haloes: scatter and the dependence on mass and environment

We use a series of cosmological N-body simulations for a flat Λ cold dark matter (ΛCDM) cosmology to investigate the structural properties of dark matter haloes, at redshift zero, in the mass range 3 × 109 h−1 ≲Mvir ≲ 3 × 1013 h−1 M⊙. These properties include the concentration parameter, c, the spin parameter, λ, and the mean axis ratio, . For the concentration-mass relation we find c∝ in agreement with the model proposed by Bullock et al., but inconsistent with the alternative model of Eke et al. The normalization of the concentration-mass relation, however, is 15 per cent lower than suggested by Bullock et al. The results for λ and are in good agreement with previous studies, when extrapolated to the lower halo masses probed here, while c and λ are anticorrelated, in that high-spin haloes have, on average, lower concentrations. In an attempt to remove unrelaxed haloes from the sample, we compute for each halo the offset parameter, xoff, defined as the distance between the most bound particle and the centre of mass, in units of the virial radius. Removing haloes with large xoff increases the mean concentration by ∼10 per cent, lowers the mean spin parameter by ∼15 per cent, and removes the most prolate haloes. In addition, it largely removes the anticorrelation between c and λ, though not entirely. We also investigate the relation between halo properties and their large-scale environment density. For low-mass haloes we find that more concentrated haloes live in denser environments than their less concentrated counterparts of the same mass, consistent with recent correlation function analyses. Note, however, that the trend is weak compared to the scatter. For the halo spin parameters we find no environment dependence, while there is a weak indication that the most spherical haloes reside in slightly denser environments. Finally, using a simple model for disc galaxy formation we show that haloes that host low surface brightness galaxies are expected to be hosted by a biased subset of haloes. Not only do these haloes have spin parameters that are larger than average, they also have concentration parameters that are ∼15 per cent lower than the average at a given halo mass. We discuss the implications of all these findings for the claimed disagreement between halo concentrations inferred from low surface brightness rotation curves, and those expected for a ΛCDM cosmolog

Concentration, Spin and Shape of Dark Matter Haloes: Scatter and the Dependence on Mass and Environment

We use a series of cosmological N-body simulations for a flat LCDM cosmology to investigate the properties of dark matter haloes in the mass range 3.0e9-3.0e13 Msun. These properties include the concentration parameter (c), the spin parameter (lambda) and the mean axis ratio (q). For the concentration-mass relation we find c~M^(-0.11) in agreement with the model proposed by Bullock et al. even if we find a lower normalization (15%). The results for lambda and q are in good agreement with previous studies, while c and lambda are anti-correlated. In an attempt to remove unrelaxed haloes, we use the offset parameter (xoff), defined as the distance between the most bound particle and the center of mass. Removing haloes with large xoff increases the c by ~10%, lowers the lambda by ~15%, and removes the most prolate haloes. In addition, it largely removes the anti-correlation between c and lambda though not entirely. We also investigate the effects of the large-scale environment. We find that more concentrated haloes live in denser environments. Note, however, that the trend is weak compared to the scatter. For the spin parameters we find no environment dependence, while there is a weak indication that the most spherical haloes reside in denser region. Finally, using a simple model for disk galaxy formation we show that haloes that host low surface brightness galaxies are expected to be hosted by a biased sub-set of haloes. Not only do these haloes have spin parameters that are larger than average, they also have c that are 15% percent lower than the average at a given halo mass. We discuss the implications of all these findings for the claimed disagreement between halo concentrations inferred from LSB rotation curves, and those expected for a LCDM cosmology. (abridged)Comment: 23 pages, 14 figure. Resolution and environment effects discussed in more details. Conclusions unchanged. References added. Accepted for publication by MNRAS. A preprint with high-resolution figures is available at http://www-theorie.physik.unizh.ch/~andrea/ConcParam

Strontium and Oxygen Isotope Profiles of Sequentially Sampled Modern Bison (Bison bison bison) Teeth from Interior Alaska as Proxies of Seasonal Mobility

Studies addressing prehistoric mobility in animals typically use isotopic analyses of sequentially formed tissues, such as the growth layers in teeth, to infer physical movement on the landscape. Strontium isotope ratios (87Sr/86Sr values), which vary geographically, are particularly useful for this purpose, especially when paired with stable oxygen isotope ratios (δ18O), which vary seasonally. Together, these two isotope systems can provide information about past animal movement patterns on a seasonal scale. However, while many studies have used 87Sr/86Sr and δ18O values from analyses of sequentially formed tissues for this purpose, there have been limited analyses on modern animals of known movement patterns across high-latitude regions. In this pilot study, we sequentially sampled and analyzed one second molar (M2) and two third molars (M3) from two bison (Bison bison bison) from the Delta bison herd, which resides in interior Alaska and has known and documented seasonal mobility patterns. The resulting 87Sr/86Sr values from the teeth were compared to a high-resolution 87Sr/86Sr isoscape for the region and were paired with δ18O analyses to determine whether the seasonal 87Sr/86Sr values matched the predicted values for each of the seasonal bison habitat areas. The results indicate that the 87Sr/86Sr and δ18O values reliably reflected the known seasonal mobility patterns of bison and suggest that this approach could be used to investigate the mobility patterns of prehistoric bison in Alaska and surrounding high-latitude regions.En général, les études qui portent sur la mobilité des animaux préhistoriques se servent d’analyses isotopiques des tissus séquentiellement formés, y compris les couches de développement des dents, afin d’en déduire les mouvements physiques dans l’environnement. Les rapports isotopiques du strontium (87Sr/86Sr) sont particulièrement utiles à cette fin, car ils varient géographiquement, surtout lorsqu’ils sont jumelés avec les rapports isotopiques stables de l’oxygène (δ18O), dont la variabilité est saisonnière. Ensemble, ces deux isotopes peuvent fournir des informations sur les habitudes de déplacement des animaux dans un paysage en fonction des saisons. Cependant, même si plusieurs études ont utilisé les valeurs 87Sr/86Sr et δ18O découlant des analyses des tissus séquentiellement formés à cette fin, peu d’analyses ont été effectuées chez les animaux modernes dont les habitudes de déplacement sont connues dans les régions de haute latitude. Dans cette étude pilote, nous avons séquentiellement échantillonné et analysé une deuxième molaire (M2) et deux troisièmes molaires (M3) de deux bisons (Bison bison bison) du troupeau de bisons du delta, troupeau qui réside dans l’intérieur de l’Alaska et dont les modèles de mobilité saisonnière sont connus et documentés. Les valeurs 87Sr/86Sr obtenues à partir des dents ont été comparées à un paysage isotopique de haute résolution 87Sr/86Sr pour la région et ont été jumelées aux analyses δ18O pour déterminer si les valeurs 87Sr/86Sr saisonnières correspondaient aux valeurs prévues pour les zones d’habitat saisonnières du bison. Les résultats indiquent que les valeurs 87Sr/86Sr et δ18O reflètent fidèlement les modèles connus de mobilité saisonnière du bison, et suggèrent que cette méthode pourrait servir à étudier les modèles de mobilité des bisons préhistoriques en Alaska et dans les régions de haute latitude environnantes

Two contemporaneous mitogenomes from terminal Pleistocene burials in eastern Beringia

Pleistocene residential sites with multiple contemporaneous human burials are extremely rare in the Americas. We report mitochondrial genomic variation in the first multiple mitochondrial genomes from a single prehistoric population: two infant burials (USR1 and USR2) from a common interment at the Upward Sun River Site in central Alaska dating to ~11,500 calendar years before present (cal B.P.). Using a targeted capture method and next-generation sequencing we determined that the USR1 infant possessed variants that define mitochondrial lineage C1b, while the USR2 genome falls at the root of lineage B2, allowing us to refine younger coalescence age estimates for these two clades. C1b and B2 are rare to absent in modern populations of Northern North America. Documentation of these lineages at this location in the Late Pleistocene provides evidence for the extent of mitochondrial diversity in early Beringian populations, which supports the expectations of the Beringian Standstill Model

Body Mass Index and Mortality, Recurrence and Readmission after Myocardial Infarction : Systematic Review and Meta-analysis

Acknowledgments: The authors thank the contribution of Lee Hooper, University of East Anglia, who has provided supervision of Kafri’s work which contributed to this paper. Funding: This research received no external funding.Peer reviewedPublisher PD

Serum albumin and post stroke outcomes : Analysis of UK Regional Registry Data, Systematic Review, and Meta-analysis

Acknowledgments We would like to acknowledge the Norfolk and Norwich Stroke and TIA Register for providing the data. We would also like to acknowledge the valuable input of Melanie Bickerton, the University of Aberdeen Medical Library, for ensuring a comprehensive and well-designed search strategy.Peer reviewe

New insights into Eastern Beringian mortuary behavior: A terminal Pleistocene double infant burial at Upward Sun River

Here we report on the discovery of two infant burials dating to 11,500 calibrated years (cal) B.P. at the Upward Sun River site in central Alaska. The infants were interred in a pit feature with associated organic and lithic grave goods, including the earliest known North American hafted bifaces with decorated antler foreshafts. Skeletal and dental analyses indicate that Individual 1 died shortly after birth and Individual 2 was a late-term fetus, making these the youngest-aged late Pleistocene individuals known for the Americas and the only known prenate, offering, to our knowledge, the first opportunity to explore mortuary treatment of the youngest members of a terminal Pleistocene North American population. This burial was situated 40 cm directly below a cremated 3-y-old child previously discovered in association with a central hearth of a residential feature. The burial and cremation are contemporaneous, and differences in body orientation, treatment, and associated grave goods within a single feature and evidence for residential occupation between burial episodes indicate novel mortuary behaviors. The human remains, grave goods, and associated fauna provide rare direct data on organic technology, economy, seasonality of residential occupations, and infant/child mortality of terminal Pleistocene Beringians

Dark Matter Direct Detection with Non-Maxwellian Velocity Structure

The velocity distribution function of dark matter particles is expected to show significant departures from a Maxwell-Boltzmann distribution. This can have profound effects on the predicted dark matter - nucleon scattering rates in direct detection experiments, especially for dark matter models in which the scattering is sensitive to the high velocity tail of the distribution, such as inelastic dark matter (iDM) or light (few GeV) dark matter (LDM), and for experiments that require high energy recoil events, such as many directionally sensitive experiments. Here we determine the velocity distribution functions from two of the highest resolution numerical simulations of Galactic dark matter structure (Via Lactea II and GHALO), and study the effects for these scenarios. For directional detection, we find that the observed departures from Maxwell-Boltzmann increase the contrast of the signal and change the typical direction of incoming DM particles. For iDM, the expected signals at direct detection experiments are changed dramatically: the annual modulation can be enhanced by more than a factor two, and the relative rates of DAMA compared to CDMS can change by an order of magnitude, while those compared to CRESST can change by a factor of two. The spectrum of the signal can also change dramatically, with many features arising due to substructure. For LDM the spectral effects are smaller, but changes do arise that improve the compatibility with existing experiments. We find that the phase of the modulation can depend upon energy, which would help discriminate against background should it be found.Comment: 34 pages, 16 figures, submitted to JCAP. Tables of g(v_min), the integral of f(v)/v from v_min to infinity, derived from our simulations, are available for download at http://astro.berkeley.edu/~mqk/dmdd

Orthostatic hypertension and major adverse events: a systematic review and meta-analysis

Aims: The role of orthostatic hypertension (OHT) in cardiovascular disease (CVD) and mortality is unclear. We aimed to determine if this association exists through a systematic review and meta-analysis. Methods and results: Study inclusion criteria included: (i) any observational/interventional studies of participants aged ≥18 years (ii) that assessed the relationship between OHT and (iii) at least one outcome measure—all-cause mortality (primary outcome), coronary heart disease, heart failure, stroke/cerebrovascular disease, or neurocognitive decline. MEDLINE, EMBASE, Cochrane, clinicaltrials.gov, and PubMed were independently searched by two reviewers (inception—19 April 2022). Critical appraisals were conducted using the Newcastle–Ottawa Scale. Random-effects meta-analysis was performed using a generic inverse variance method, and narrative synthesis or pooled results were presented as an odds or hazards ratio (OR/HR), with 95% confidence interval. Twenty studies (n = 61 669; 47.3% women) were eligible, of which 13 were included in the meta-analysis (n = 55 456; 47.3% women). Median interquartile range (IQR) follow-up for prospective studies was 7.85 (4.12, 10.83) years. Eleven studies were of good quality, eight fair, and one poor. Relative to orthostatic normotension (ONT), systolic OHT (SOHT) was associated with a significant 21% greater risk of all-cause mortality (HR: 1.21, 1.05–1.40), 39% increased risk of CVD mortality based on two studies (HR: 1.39, 1.05–1.84), and near doubled odds of stroke/cerebrovascular disease (OR: 1.94, 1.52–2.48). The lack of association with other outcomes may be due to weak evidence or low statistical power. Conclusion: Patients with SOHT may have higher mortality risk relative to those with ONT and increased odds of stroke/cerebrovascular disease. Whether interventions can reduce OHT and improve outcomes should be explored

The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies

Context and Objective: The impact of existing malnutrition on stroke outcomes is poorly recognised and treated. Evidence was systematically reviewed and quantified by meta-analysis. Methods: MEDLINE, EMBASE and Web of Science were searched from inception to 11 January 2021 and updated in July. Prospective cohort studies, in English, evaluating anthropometric and biomarkers of nutrition on stroke outcomes were included. Risk of bias was assessed using the Scottish Intercollegiate Guidelines Network checklist. Results: Twenty-six studies (n = 156 249) were eligible (follow-up: One month-14 years). Underweight patients had increased risk of long-term mortality (adjusted hazard ratio = 1.65,1.41-1.95), whilst overweight (0.80,0.74-0.86) and obese patients (0.80,0.75-0.85) had decreased risk compared to normal weight. Odds of mortality decreased in those with high serum albumin (odds ratio = 0.29,0.18-0.48) and increased with low serum albumin (odds ratio = 3.46,1.78-6.74) compared to normal serum albumin (30-35 g/L). Being malnourished compared to well-nourished, as assessed by the Subjective Global Assessment (SGA) or by a combination of anthropometric and biochemical markers increased all-cause mortality (odds ratio = 2.38,1.85-3.06) and poor functional status (adjusted odds ratio = 2.21,1.40-3.49). Conclusion: Nutritional status at the time of stroke predicts adverse stroke outcomes