Seasonal climate predictions in support of water reservoirs management in Spain

Póster presentado en: 1st Climateurope festival celebrado en Valencia, del 5 al 7 de abril de 2017.This work has been partially funded by the FP7 EUPORIAS projec

La actividad física como elemento de participación y calidad de vida en las personas mayores

This study investigated participation in physical activity as an element that improves health and quality of life among elderly people. We present a descriptive analysis using secondary data to explore their attitudes toward physical activity, its frequency, and characteristics. The following categories were analysed: population structure by sex and age; quality of life and perceived health; lifestyles and daily activities; and the characteristics of physical activities among elderly people. To increase the comparative and analytical power of the study, all age ranges were included in each variable. The results highlight the good state of health and high participation in physical activity among elderly people compared to other age groups.El presente trabajo relaciona la participación a través de la actividad física como elemento que contribuye a la salud y la calidad de vida de las personas mayores. Así desarrolla un análisis de tipo descriptivo con datos secundarios que pretende explorar la posición del colectivo de personas mayores en relación a la actividad física, su incidencia y características con el objetivo de indagar su mayor o menor importancia en relación a la calidad de vida en este grupo de edad. Las categorías de análisis que articulan los resultados se agrupan en: estructura de la población mayor por sexo y edad, calidad de vida y salud percibida, estilos de vida y actividades cotidianas y principales características de la actividad física en personas mayores. Para aumentar la capacidad comparativa y de análisis se ha incluido la totalidad de tramos de edad en cada una de las variables. Entre los resultados se destaca el buen estado de salud y la alta participación en actividades física de las personas mayores en comparación con otros grupos de edad

Análisis y propuestas de mejora del Programa Integrado de Segundo Ciclo de la Universidad de Mayores "José Saramago" de la Universidad de Castilla-La Mancha

El presente trabajo pretende ofrecer un análisis de las fortalezas y debilidades tanto organizativas como pedagógicas del Segundo Ciclo Integrado de la Universidad de Castilla La Mancha. Para ello se presentan los datos obtenidos tanto de las evaluaciones realizadas a los alumnos en diferentes cursos académicos como de una entrevista estructurada realizada al coordinador del segundo ciclo en la sede de Talavera de la Reina. En la entrevista se explora la visión que sobre los aspectos organizativos y didácticos sostiene este agente. Consideramos que conocer la visión que sobre estos aspectos tienen los coordinadores, nos permitirá acercarnos a los diferentes estilos de gestión por ellos desarrollados y recabar información sobre aspectos a mejorar que redunden en una mayor calidad educativa de los mismos

Seasonal forecasts of winter reservoirs inflow

Vídeo elaborado con motivo de la celebración del 15º Mediterranean Climate Outlook Forum (MedCOF) desarrollado de forma online entre el 15 de octubre y el 24 de noviembre de 2020

Demographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain : The SEPAR National Registry

Little is known on the characteristics of patients diagnosed with idiopathic pulmonary fibrosis (IPF) in Spain. We aimed to characterize the demographic and clinical profile of IPF patients included in the IPF National Registry of the Spanish Respiratory Society (SEPAR). This is a prospective, observational, multicentre and nationwide study that involved 608 IPF patients included in the SEPAR IPF Registry up to June 27th, 2017, and who received any treatment for their disease. IPF patients were predominantly males, ex-smokers, and aged in their 70s, similar to other registries. Upon inclusion, mean ± SD predicted forced vital capacity was 77.6% ± 19.4, diffusing capacity for carbon monoxide was 48.5% ± 17.7, and the 6-min walk distance was 423.5 m ± 110.4. The diagnosis was mainly established on results from the high-resolution computed tomography in the proper clinical context (55.0% of patients), while 21.2% of patients required invasive procedures (surgical lung biopsy) for definitive diagnosis. Anti-fibrotic treatment was prescribed in 69.4% of cases, 51.5% pirfenidone and 17.9% nintedanib, overall with a good safety profile. The SEPAR IPF Registry should help to further characterize current characteristics and future trends of IPF patients in Spain and compare/pool them with other registries and cohorts

Chronic lymphocytic leukemia with isochromosome 17q: An aggressive subgroup associated with TP53 mutations and complex karyotypes

Although i(17q) [i(17q)] is frequently detected in hematological malignancies, few studies have assessed its clinical role in chronic lymphocytic leukemia (CLL). We recruited a cohort of 22 CLL patients with i(17q) and described their biological characteristics, mutational status of the genes TP53 and IGHV and genomic complexity. Furthermore, we analyzed the impact of the type of cytogenetic anomaly bearing the TP53 defect on the outcome of CLL patients and compared the progression-free survival (PFS) and overall survival (OS) of i(17q) cases with those of a group of 38 CLL patients harboring other 17p aberrations. We detected IGHV somatic hypermutation in all assessed patients, and TP53 mutations were observed in 71.4% of the cases. Patients with i(17q) were more commonly associated with complex karyotypes (CK) and tended to have a poorer OS than patients with other anomalies affecting 17p13 (median OS, 44 vs 120 months, P = 0.084). Regarding chromosomal alterations, significant differences in the median OS were found among groups (P = 0.044). In conclusion, our findings provide new insights regarding i(17q) in CLL and show a subgroup with adverse prognostic features.Peer Reviewe

Chronic lymphocytic leukemia with isochromosome 17q: An aggressive subgroup associated with TP53 mutations and complex karyotypes

Although i(17q) [i(17q)] is frequently detected in hematological malignancies, few studies have assessed its clinical role in chronic lymphocytic leukemia (CLL). We recruited a cohort of 22 CLL patients with i(17q) and described their biological characteristics, mutational status of the genes TP53 and IGHV and genomic complexity. Furthermore, we analyzed the impact of the type of cytogenetic anomaly bearing the TP53 defect on the outcome of CLL patients and compared the progression-free survival (PFS) and overall survival (OS) of i(17q) cases with those of a group of 38 CLL patients harboring other 17p aberrations. We detected IGHV somatic hypermutation in all assessed patients, and TP53 mutations were observed in 71.4% of the cases. Patients with i(17q) were more commonly associated with complex karyotypes (CK) and tended to have a poorer OS than patients with other anomalies affecting 17p13 (median OS, 44 vs 120 months, P = 0.084). Regarding chromosomal alterations, significant differences in the median OS were found among groups (P = 0.044). In conclusion, our findings provide new insights regarding i(17q) in CLL and show a subgroup with adverse prognostic features.Depto. de Bioquímica y Biología MolecularFac. de FarmaciaTRUEpu

I.amAble: science as a vehicle towards full inclusion

En este proyecto de innovación se persigue enriquecer la formación de los estudiantes de las facultades de ciencias (F. CC.FF. y F. CC.QQ.) mediante una propuesta teórico-práctica basada en la metodología Aprendizaje-Servicio (ApS) y encaminada a facilitar la inclusión de personas con diversidad funcional, especialmente diversidad cognitiva. El proyecto parte del diseño de talleres científicos por los estudiantes universitarios para ser realizados por parejas de estudiantes preuniversitarios de manera colaborativa e inclusiva, ya que un miembro de la pareja procederá de un centro de educación especial y el otro de un centro educativo ordinario (colegio o Instituto de educación secundaria) de la Comunidad de Madrid. Tanto el diseño de los experimentos como su eventual puesta en práctica serán supervisados por los integrantes del proyecto: estudiantes de doctorado, personal de administración y servicios (PAS) y personal docente e investigador (PDI), así como por los colaboradores externos, tanto de centros de educación especial como de centros de enseñanza ordinarios. También se contará con la asesoría pedagógica de PDI de la Facultad de Educación. Las fichas didácticas elaboradas por los estudiantes se harán públicas en la página web del proyecto, vinculada a la Universidad Complutense bajo el nombre I.amAble. Esta plataforma, ya existente, será perfeccionada por estudiantes y PDI de la Facultad de Informática y del Instituto de Tecnología del Conocimiento. De esta manera estarán disponibles con un diseño lo más intuitivo y accesible posible para quienes estén interesados en la divulgación científica desde una perspectiva inclusiva. El equipo informático también desarrollará herramientas que faciliten la elaboración de las fichas como, por ejemplo, la transcripción de textos a pictogramas. El proyecto puede mejorar la calidad de la formación de nuestros estudiantes, desde los aspectos más académicos hasta los más humanistas, como son la profundización en algunos conceptos y su aplicación práctica, el desarrollo de estrategias de comunicación e improvisación, la capacidad de empatía o su contribución al desarrollo del tejido social. Todo ello facilitará su inserción laboral, especialmente en el ámbito de la educación, tanto formal como informal (museos, animación sociocultural, etc.). Este proyecto también contribuirá a la mejora de la cultura científica y a la percepción de nuestra universidad como un espacio abierto a la sociedad y que está a su servicio. Además, facilitará la inclusión de las personas con diversidad funcional mediante el acercamiento compartido a la ciencia.This innovation project seeks to enrich the training of students of science faculties through a theoretical-practical proposal based on the Learning-Service methodology and aimed at facilitating the inclusion of people with functional diversity, especially cognitive diversity. The project is based on the design of scientific workshops by university students to be carried out by pairs of pre-university students in a collaborative and inclusive manner, since one member of the couple will come from a special education center and the other from an ordinary educational center of the Community of Madrid. Both the design of the experiments and their eventual implementation will be supervised by the project members: doctoral students, administration and service staff and teaching and research staff, as well as external collaborators from special education centers as well as ordinary education centers. There will also be pedagogical advisory from the Faculty of Education. The didactic sheets elaborated by the students will be made public on the web page of the project, linked to the Complutense University under the name I.amAble. This platform, already existing, will be improved by students and staff from the IT Faculty and the Institute of Technology of Knowledge. In this way they will be available with a design as intuitive and accessible as possible for those interested in scientific dissemination from an inclusive perspective. The IT team will also develop tools that facilitate the preparation of the files, for example, the transcription of texts to pictograms. The project can improve the quality of the training of our students, from the most academic aspects to the most humanistic ones, such as the deepening of some concepts and their practical application, the development of communication and improvisation strategies, the capacity for empathy or contribution to the development of the social fabric. All this will facilitate their labor insertion, especially in the field of education, both formal and informal (museums, sociocultural animation, etc.). This project will also contribute to the improvement of scientific culture and to the perception of our university as a space open to society and at its service. In addition, it will facilitate the inclusion of people with functional diversity through a shared approach to science.Fac. de Ciencias QuímicasFALSEUniversidad Complutense de MadridReal Sociedad Española de Química - Sección Territorial de MadridCiencias Sin BarrerasConsejería de Educación e Investigación de la Comunidad de Madridsubmitte