228 research outputs found

    Emotional Intelligence Instruction For Millennials In Undergraduate Education

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    The purpose of this study was to examine the improvement, if any, of emotional intelligence scores of students who participated in and completed the specified professional development seminar. In addition, this study aimed to examine the relationship between emotional intelligence subscales of students enrolled in a professional development seminar that focuses on enhancing the emotional intelligence. The research design for this study was an ex post facto, quasi-experimental correlational quantitative research design. Data from the 371 students who enrolled in the Professional Development Seminar course during academic years 2015-2017 served as the sample for this study. This study focused on one central research question: Is there a change in students’ emotional intelligence scores from the pre-test EQ-i 2.0 assessment administration to the post-test EQ-i 2.0 assessment administration after completing a Professional Development Seminar aimed at improving students’ emotional intelligence? The results of this research revealed that instruction that focuses specifically on the various aspects of emotional intelligence can have a significant impact on students’ emotional intelligence and can positively improve EQ-i 2.0 subscales. Out of the fifteen EQ-i 2.0 subscales, only two resulted in improvements that were not statistically significant While not statistically significant, the study results indicate that improvements did occur. On the other hand, thirteen EQ-i 2.0 subscales resulted in improvements that were significant. This study’s results provide evidence that emotional intelligence is an ability that can be improved upon if students receive specific instruction focusing on emotional intelligence. The impact of this study is significant in that it reveals that colleges and universities can create and deliver EQ-related instruction and affect students’ emotional intelligence. After graduating, students will be better prepared to succeed in the professional environment, and employers can expect to hire college graduates who possess one of the most highly desired employment traits, emotional intelligence. This study is evidence that provides a promising outlook on these efforts

    Limiting conditional distributions for birth-death processes

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    In a recent paper one of us identified all of the quasi-stationary distributions for a non-explosive, evanescent birth-death process for which absorption is certain, and established conditions for the existence of the corresponding limiting conditional distributions. Our purpose is to extend these results in a number of directions. We shall consider separately two cases depending on whether or not the process is evanescent. In the former case we shall relax the condition that absorption is certain. Furthermore, we shall allow for the possibility that the minimal process might be explosive, so that the transition rates alone will not necessarily determine the birth-death process uniquely. Although we shall be concerned mainly with the minimal process, our most general results hold for any birth-death process whose transition probabilities satisfy both the backward and the forward Kolmogorov differential equations

    Dynamics of a structured slug population model in the absence of seasonal variation

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    We develop a novel, nonlinear structured population model for the slug Deroceras reticulatum, a highly significant agricultural pest of great economic impact, in both organic and non-organic settings. In the absence of seasonal variations, we numerically explore the effect of life history traits that are dependent on an individual's size and measures of population biomass. We conduct a systematic exploration of parameter space and highlight the main mechanisms and implications of model design. A major conclusion of this work is that strong size dependent predation significantly adjusts the competitive balance, leading to non-monotonic steady state solutions and slowly decaying transients consisting of distinct generational cycles. Furthermore, we demonstrate how a simple ratio of adult to juvenile biomass can act as a useful diagnostic to distinguish between predated and non-predated environments, and may be useful in agricultural settings

    Magnetic field tunable vortex diode made of YBa2Cu3O7−δ Josephson junction asymmetrical arrays

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    Several Josephson ratchets designed as asymmetrically structured parallel-series arrays of Josephson junctions made of YBa2Cu3O7−δ have been fabricated. From the current-voltage characteristics measured for various values of applied magnetic field, B, in the temperature range of 10–89 K, we demonstrate that the devices work as magnetic field-tunable highly reversible vortex diodes. Thus, at 89 K, the ratchet efficiency η could be reversed from +60% to −60% with a change in B as small as 3 μT. By decreasing the operation temperature, η improves up to −95% at 10 K while the dynamics in the B-tunability degrades. The ratchet designs we propose here can be used to control unidirectional vortex flow vortices in superconducting devices as well as building integrated nano-magnetic sensors. Numerical simulations qualitatively confirm our experimental findings and also provide insight into the related and more general problem of the control of the transport of nano/quantum objects in thin films

    Cortical AAV-CNTF gene therapy combined with intraspinal mesenchymal precursor cell transplantation promotes functional and morphological outcomes after spinal cord injury in adult rats

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    Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the cerebral cortex promotes plasticity and regrowth of axons projecting into the female adult F344 rat spinal cord after moderate thoracic (T10) contusion injury (SCI). Cortical neurons were transduced with a bicistronic adeno-associated viral vector (AAV1) expressing a secretory form of CNTF coupled to mCHERRY (AAV-CNTFmCherry) or with control AAV only (AAV-GFP) two weeks prior to SCI. In some animals, viable or nonviable F344 rat mesenchymal precursor cells (rMPCs) were injected into the lesion site two weeks after SCI to modulate the inhibitory environment. Treatment with AAV-CNTFmCherry, as well as with AAV-CNTFmCherry combined with rMPCs, yielded functional improvements over AAV-GFP alone, as assessed by open-field and Ladderwalk analyses. Cyst size was significantly reduced in the AAV-CNTFmCherry plus viable rMPC treatment group. Cortical injections of biotinylated dextran amine (BDA) revealed more BDA-stained axons rostral and alongside cysts in the AAV-CNTFmCherry versus AAV-GFP groups. After AAV-CNTFmCherry treatments, many sprouting mCherry-immunopositive axons were seen rostral to the SCI, and axons were also occasionally found caudal to the injury site. These data suggest that CNTF has the potential to enhance corticospinal repair by transducing parent CNS populations

    On the computational power of probabilistic and quantum branching program

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    In this paper, we show that one-qubit polynomial time computations are as powerful as NC1 circuits. More generally, we define syntactic models for quantum and stochastic branching programs of bounded width and prove upper and lower bounds on their power. We show that any NC1 language can be accepted exactly by a width-2 quantum branching program of polynomial length, in contrast to the classical case where width 5 is necessary unless NC 1 = ACC. This separates width-2 quantum programs from width-2 doubly stochastic programs as we show the latter cannot compute the middle bit of multiplication. Finally, we show that bounded-width quantum and stochastic programs can be simulated by classical programs of larger but bounded width, and thus are in NC1. For read-once quantum branching programs (QBPs), we give a symmetric Boolean function which is computable by a read-once QBP with O (log n) width, but not by a deterministic read-once BP with o (n) width, or by a classical randomized read-once BP with o (n) width which is "stable" in the sense that its transitions depend on the value of the queried variable but do not vary from step to step. Finally, we present a general lower bound on the width of read-once QBPs, showing that our O (log n) upper bound for this symmetric function is almost tight. © 2005 Elsevier Inc. All rights reserved

    Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.

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    A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at this locus that are related to the etiopathology of CRC, we used microarray-based target selection methods, coupled to next-generation sequencing, to study 103 kb at the 11q23 locus. We genotyped 369 putative variants from 1,030 patients with CRC (cases) and 1,061 individuals without CRC (controls) from the Ontario Familial Colorectal Cancer Registry. Two previously uncharacterized genes, COLCA1 and COLCA2, were found to be co-regulated genes that are transcribed from opposite strands. Expression levels of COLCA1 and COLCA2 transcripts correlate with rs3802842 genotypes. In colon tissues, COLCA1 co-localizes with crystalloid granules of eosinophils and granular organelles of mast cells, neutrophils, macrophages, dendritic cells and differentiated myeloid-derived cell lines. COLCA2 is present in the cytoplasm of normal epithelial, immune and other cell lineages, as well as tumor cells. Tissue microarray analysis demonstrates the association of rs3802842 with lymphocyte density in the lamina propria (p = 0.014) and levels of COLCA1 in the lamina propria (p = 0.00016) and COLCA2 (tumor cells, p = 0.0041 and lamina propria, p = 6 × 10(-5)). In conclusion, genetic, expression and immunohistochemical data implicate COLCA1 and COLCA2 in the pathogenesis of colon cancer. Histologic analyses indicate the involvement of immune pathways

    Identification and evaluation of epidemic prediction and forecasting reporting guidelines : a systematic review and a call for action

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    NGR reports funding by NIGMS grant R35GM119582. BMA is supported by Bill and Melinda Gates Foundation through the Global Good Fund. SP and IMB were funded by the Armed Forces Health Surveillance Branch (GEIS: P0116_19_WR_03.11).Introduction: High quality epidemic forecasting and prediction are critical to support response to local, regional and global infectious disease threats. Other fields of biomedical research use consensus reporting guidelines to ensure standardization and quality of research practice among researchers, and to provide a framework for end-users to interpret the validity of study results. The purpose of this study was to determine whether guidelines exist specifically for epidemic forecast and prediction publications. Methods: We undertook a formal systematic review to identify and evaluate any published infectious disease epidemic forecasting and prediction reporting guidelines. This review leveraged a team of 18 investigators from US Government and academic sectors. Results: A literature database search through May 26, 2019, identified 1467 publications (MEDLINE n = 584, EMBASE n = 883), and a grey-literature review identified a further 407 publications, yielding a total 1777 unique publications. A paired-reviewer system screened in 25 potentially eligible publications, of which two were ultimately deemed eligible. A qualitative review of these two published reporting guidelines indicated that neither were specific for epidemic forecasting and prediction, although they described reporting items which may be relevant to epidemic forecasting and prediction studies. Conclusions: This systematic review confirms that no specific guidelines have been published to standardize the reporting of epidemic forecasting and prediction studies. These findings underscore the need to develop such reporting guidelines in order to improve the transparency, quality and implementation of epidemic forecasting and prediction research in operational public health.Publisher PDFPeer reviewe
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