Processos de redução e geração de porosidade nos turbiditos Caruaçu da Formação Maracangalha do Campo de gás de Jacuípe, Cretáceo Inferior, Bacia do Recôncavo, Bahia

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Andean tectonism of the Hualfín, Capillitas and southern Aconquija Ranges, Catamarca Province

Las Sierras Pampeanas septentrionales están integradas por bloques de basamento cristalino basculados por fallas de rumbo NE-SO, que forman parte del lineamiento de Aconquija o de Tucumán. Las unidades cenozoicas, dispuestas en los valles intramontanos que separan las sierras de Capillitas, Hualfín y Aconquija, presentan relaciones de inconformidad sobre el basamento y registran cuatro sucesivos eventos deformacionales andinos. El primer evento deformacional presenta estratos de sincrecimiento asociados a fallas normales en la Formación Hualfin. Durante el segundo evento, la Formación Hualfin fue intensamente plegada y erosionada previamente a la depositación del Complejo Volcánico Farallón Negro. El tercer evento, de carácter transtensivo, se registra en el Compelo Volcánico Farallón Negro con fallas normales y discordancias progresivas. Este evento es coincidente con la irrupción del vulcanismo en la cuenca. A los fines de analizar la cinemática de la cuarta y última etapa de deformación se realizaron mediciones de indicadores cinemáticos a lo largo de fallas regionales y estructuras menores, con resultados que reflejan desplazamientos dextrales transpresivos. Los desplazamientos correspondientes a esta etapa estarían asociados a la elevación de las sierras y el emplazamiento de cuerpos subvolcánicos, algunos de los cuales como los de cerro Atajo, Capillitas y Agua Rica entre otros, son de interés económico. La tectónica transpresiva, aún vigente, se registra en fallas activas asociadas a avalanchas y flujos de detritos provenientes de las laderas de las sierras.The northern Sierras Pampeanas in the Tucumán - Catamarca boundary are mainly composed of crystalline basement rocks, tilted by NE-SW strike faults that form part of the Aconquija and Tucumán lineaments. The Capillitas, Hualfín and Aconquija Ranges are separated by intermountain valleys filled with Tertiary volcanic and sedimentary rocks deposited unconformably over the crystalline basement. These units were affected by four different deformation events during the Andean orogenic cycle. The first one is associated to normal faults that controlled the deposition of the Hualfín Formation, evidenced by development of growth strata. During the second event, the Hualfín Formation was intensively folded and eroded prior to the deposition of the Farallón Negro Volcanic Complex (CVFN). The third event was transtensive and recorded by the Farallón Negro volcanic complex, with the development of normal faults and intraformational progressive uncomformities. This event is concordant with the initial stages of the volcanism in the region. In order to make a strain analysis of the fourth and last deformation event, kynematic indicators were measured on regional and minors faults. Results suggest dextral movements of faults and transpressive conditions. Mountain uplift and intrusion of subvolcanic rocks as well as ore deposition are related to these movements, e.g., in Cerro Atajo, Capillitas and Agua Rica. Transpressive conditions are still active today, as shown by recent debris avalanches and debris flow deposits associated to main faults.Fil: Seggiaro, Raul Eudocio. Secretaría de Industria y Minería. Servicio Geológico Minero Argentino; Argentina. Universidad Nacional de Salta. Facultad de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Caffe, Pablo Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Jujuy. Universidad Nacional de Jujuy. Centro de Investigaciones y Transferencia de Jujuy; ArgentinaFil: Becchio, Raul Alberto. Universidad Nacional de Salta. Facultad de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones en Energía no Convencional. Universidad Nacional de Salta. Facultad de Ciencias Exactas. Departamento de Física. Instituto de Investigaciones en Energía no Convencional; ArgentinaFil: Galli, Claudia Inés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Salta. Facultad de Ciencias Naturales; Argentina. Universidad Nacional de Jujuy. Facultad de Ingeniería; ArgentinaFil: Arnosio, José Marcelo. Universidad Nacional de Salta. Facultad de Ciencias Naturales. Instituto Geonorte; ArgentinaFil: Da Poian, Gabriela. Universidad Nacional de Río Negro; Argentina. Universidad Nacional de Río Negro. Sede Alto Valle. Instituto de Investigaciones en Paleobiología y Geología; Argentin

Composição dos arenitos de bacias da margem equatorial brasileira e suas implicações de proveniência e qualidade dos potenciais reservatórios

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Estudo preliminar de paleocorrentes nos depósitos fluviais do intervalo eotriássico-eocretáceo da Bacia do Paraná na região de São Pedro do Sul, RS

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Processos de redução e geração de porosidade nos turbiditos Caruaçu da Formação Maracangalha do Campo de gás de Jacuípe, Cretáceo Inferior, Bacia do Recôncavo, Bahia

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Understanding dengue virus capsid protein disordered N‑Terminus and pep14-23-based inhibition

© 2014 American Chemical SocietyDengue virus (DENV) infection affects millions of people and is becoming a major global disease for which there is no specific available treatment. pep14-23 is a recently designed peptide, based on a conserved segment of DENV capsid (C) protein. It inhibits the interaction of DENV C with host intracellular lipid droplets (LDs), which is crucial for viral replication. Combining bioinformatics and biophysics, here, we analyzed pep14-23 structure and ability to bind different phospholipids, relating that information with the full-length DENV C. We show that pep14-23 acquires α-helical conformation upon binding to negatively charged phospholipid membranes, displaying an asymmetric charge distribution structural arrangement. Structure prediction for the N-terminal segment reveals four viable homodimer orientations that alternatively shield or expose the DENV C hydrophobic pocket. Taken together, these findings suggest a new biological role for the disordered Nterminal region, which may function as an autoinhibitory domain mediating DENV C interaction with its biological targets. The results fit with our current understanding of DENV C and pep14-23 structure and function, paving the way for similar approaches to understanding disordered proteins and improved peptidomimetics drug development strategies against DENV and similar Flavivirus infections.The authors thank T. Freitas (IMM, FMUL) for technical assistance. This work was supported by Fundação para a Ciência e Tecnologia Ministério da Educação e Ciência (FCT-MEC, Portugal) projects PTDC/QUI-BIQ/112929/2009 and PTDC/SAU-ENB/117013/2010, Calouste Gulbenkian Foundation (FCG, Portugal) project Science Frontiers Research Prize 2010, European Union project FP7-IRSES MEMPEPACROSS, Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (CNPq, Brazil, grant numbers 471239/2012-7 and 306669/2013-7) and Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ, Brazil, grant numbers E-26/102.919/2011 and E-26/110.636/2012). A.F.F. and A.H. also acknowledge FCT-MEC fellowships SFRH/BD/77609/2011 and SFRH/BPD/72037/2010, respectively. I.C.M. acknowledges consecutive funding from the FCT-MEC fellowship SFRH/BPD/74287/2010 and the Program “Investigador FCT” (IF/00772/2013 Research Contract)

Benchmarking analogue models of brittle thrust wedges

We performed a quantitative comparison of brittle thrust wedge experiments to evaluate the variability among analogue models and to appraise the reproducibility and limits of model interpretation. Fifteen analogue modeling laboratories participated in this benchmark initiative. Each laboratory received a shipment of the same type of quartz and corundum sand and all laboratories adhered to a stringent model building protocol and used the same type of foil to cover base and sidewalls of the sandbox. Sieve structure, sifting height, filling rate, and details on off-scraping of excess sand followed prescribed procedures. Our analogue benchmark shows that even for simple plane-strain experiments with prescribed stringent model construction techniques, quantitative model results show variability, most notably for surface slope, thrust spacing and number of forward and backthrusts. One of the sources of the variability in model results is related to slight variations in how sand is deposited in the sandbox. Small changes in sifting height, sifting rate, and scraping will result in slightly heterogeneous material bulk densities, which will affect the mechanical properties of the sand, and will result in lateral and vertical differences in peak and boundary friction angles, as well as cohesion values once the model is constructed. Initial variations in basal friction are inferred to play the most important role in causing model variability. Our comparison shows that the human factor plays a decisive role, and even when one modeler repeats the same experiment, quantitative model results still show variability. Our observations highlight the limits of up-scaling quantitative analogue model results to nature or for making comparisons with numerical models. The frictional behavior of sand is highly sensitive to small variations in material state or experimental set-up, and hence, it will remain difficult to scale quantitative results such as number of thrusts, thrust spacing, and pop-up width from model to nature