66 research outputs found

    Range extenders: An innovative approach to range anxiety in electric vehicles

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    Electric vehicles have been a source of major innovation but the problem of vehicle range persists. Range extenders, auxiliary power units that can be attached to vehicles as a trailer, seek to solve the problem by providing additional range during longer journeys. This study uses patent data, Social Network Analysis and qualitative data to examine the development of this technology. It finds that small firms have made significant progress in technological terms and have also designed credible business models. They have met resistance from larger vehicle manufacturers, however, whose preference is to wait for developments in battery density despite great uncertainty as to when these will come

    Sustainable energy projects and the community: mapping single building use of microgeneration technologies in London

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    Microgeneration technologies offer the potential for distributed energy supply and consumption resulting in reduced reliance on centralised generation. Adoption of microgeneration for use in community settings is usually understood as having a beneficial contribution to sustainable development. This is particularly relevant in urban environments which present specific challenges relating to the heterogeneity of building and land use. Small-scale installations in buildings also appear to offer technological flexibility at the ‘human’ level, necessary for local participation in shaping the direction of sustainable development. This paper reports on a project concerned with identifying on-site energy generation projects in Greater London. A database was compiled comprising renewable and energy efficient microgeneration installations in multi-occupancy buildings. The relationships between each project and its associated organisations are mapped as a social network, which illustrates the heterogeneity of technologies and actors involved, as well as the flows of funding and expertise. The structure of the resulting networks indicates a lack of participation by social or not-for-profit groups who are traditionally identified as community level actors. The findings indicate that large institutional actors on the supply side may become regarded as renewable energy experts. Hence, there is a need to consider how the concept of community level actors in urban microgeneration projects is applicable to local government and commercial organisations

    Adult-onset dominant muscular dystrophy in Greek families caused by Annexin A11

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    Objective: Mutations in the prion-like domain of RNA binding proteins cause dysfunctional stress responses and associated aggregate pathology in patients with neurogenic and myopathic phenotypes. Recently, mutations in ANXA11 have been reported in patients with amyotrophic lateral sclerosis and multisystem proteinopathy. Here we studied families with an autosomal dominant muscle disease caused by ANXA11:c.118G > T;p.D40Y. Methods: We performed deep phenotyping and exome sequencing of patients from four large Greek families, including seven affected individuals with progressive muscle disease but no family history of multi-organ involvement or ALS. Results: In our study, all patients presented with an autosomal dominant muscular dystrophy without any Paget disease of bone nor signs of frontotemporal dementia or Parkinson's disease. Histopathological analysis showed rimmed vacuoles with annexin All accumulations. Electron microscopy analysis showed myofibrillar abnormalities with disorganization of the sarcomeric structure and Z-disc dissolution, and subsarcolemmal autophagic material with myeloid formations. Molecular genetic analysis revealed ANXA11:c.118G > T;p.D4OY segregating with the phenotype. Interpretation: Although the pathogenic mechanisms associated with p.D4OY mutation in the prion-like domain of Annexin All need to be further clarified, our study provides robust and clear genetic evidence to support the expansion of the phenotypic spectrum of ANXA11.Peer reviewe

    A barrier and techno-economic analysis of small-scale bCHP (biomass combined heat and power) schemes in the UK

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    bCHP (Biomass combined heat and power) systems are highly efficient at smaller-scales when a significant proportion of the heat produced can be effectively utilised for hot water, space heating or industrial heating purposes. However, there are many barriers to project development and this has greatly inhibited deployment in the UK. Project viability is highly subjective to changes in policy, regulation, the finance market and the low cost fossil fuel incumbent. The paper reviews the barriers to small-scale bCHP project development in the UK along with a case study of a failed 1.5MWel bCHP scheme. The paper offers possible explanations for the project's failure and suggests adaptations to improve the project resilience. Analysis of the project's: capital structuring contract length and bankability; feedstock type and price uncertainty, and plant oversizing highlight the negative impact of the existing project barriers on project development. The research paper concludes with a discussion on the effects of these barriers on the case study project and this industry more generally. A greater understanding of the techno-economic effects of some barriers for small-scale bCHP schemes is demonstrated within this paper, along with some methods for improving the attractiveness and resilience of projects of this kind
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