Ectoparasitos de morcegos da floresta nacional dos palmares (flona palmares) – Altos, Piauí, Brasil / Ectoparasites of bats from the national forest of palmares (flona palmares) - Altos, Piauí, Brazil

Informações sobre estreblídeos, ácaros, carrapatos e seus hospedeiros são escassos no Estado do Piauí, não havendo dados disponíveis principalmente sobre ectoparasitos relacionados à quiropterofauna. Assim, neste estudo nós apresentamos a primeira lista de espécies de parasitos de morcegos da Floresta Nacional dos Palmares, estado do Piauí, nordeste do Brasil. Os ectoparasitos encontrados foram coletados com pinças e conservados em etanol a 70% para posterior análises em microscopia óptica. Foram capturados e inspecionados 42 morcegos, sendo 23 machos e 19 fêmeas, dos quais 28 estavam parasitados com moscas pertencentes a família Streblidade, carrapatos pertencentes à família Ixodidae e ácaros pertencentes a família Spinturnicidae. Este estudo relata o primeiro registro de Periglischrus iheringi e Amblyomma sp em morcegos no Piauí, contribuindo assim com informações sobre o ectoparasitismo da quiropterofauna brasileira

Índice de Desenvolvimento Como Liberdade. Uma Proposta Teórico-Metodológica de Análise

This work aims to discuss and outline a development index based on the concept of instrumental freedoms of Amartya Sen (2010), called here IDL. The main objective, develops a theoretical and methodological construction, from the perspective of instrumental freedoms of Amartya Sen to review the development. Specifically, we identify the relevant variables and measurement instruments; It proposes a mathematical formula for calculating the development index as freedom taking as reference the Brazilian reality. The theoretical references of this study were structured considering the theoretical approaches to the development, from the perspective of classical liberal school, and specifically in utilitarian thought. They add also the studies on development indicators to support the methodological approach developed here. The IDL is structured on the concept of freedom, being built from five indicators present in the work of Amartya Sen: Political Freedoms (LP), Economic Cash (DE), Social Opportunities (OS), Transparency Guarantees (GT), and Security Protective (SP). Overall, the analysis of instrumental freedoms in the Brazilian context notes that the 1988 Constitution constitutes a relevant legal framework in advance of regional development. However, the partial failure of some constitutional provisions is associated with relative deprivation of human capabilities

Endoparasitos de morcegos da Floresta Nacional de Palmares (FLONA), ALTOS – PIAUÍ, BRASIL / Bat endoparasites from the Floresta Nacional de Palmares (FLONA), ALTOS – PIAUÍ, BRAZIL

O Brasil registra atualmente 181 espécies de morcegos descritas com 68 gêneros e nove famílias. Com relação aos endoparasitos em morcegos, há um registro de 59 espécies, dentre os quais, nematóides, acantocéfalos e platelmintos. No total foram capturados 64 morcegos, dos quais 26,5% (17/64) encontravam-se parasitados por helmintos, todos nematoides. A espécie Carollia perspicillata apresentou a maior diversidade parasitária, apresentando infecção por três dos cinco gêneros de nematóides encontrados: Histiostrongylus sp., Tricholeiperia sp. e Litomosoides sp. Os morcegos Phyllostomus discolor e Sturnira lilium apresentaram infecção por Histiostrongylus coronatus. Os nematóides Histiostrongylus sp. e Tricholeiperia sp. foram encontrados infectando morcegos do gênero Trinycteris nicefori.  e o morcego Lophostoma silvícola estava parasitado por nematóides da família Ornithostrongylidae. Os resultados obtidos no presente trabalho reforçam a necessidade de maiores estudos na área de parasitologia de quirópteros, uma vez que elevados índices parasitários podem afetar o animal de diversas formas, principalmente reduzindo suas aptidões físicas

Local Fetal Lung Renin-Angiotensin System as a Target to Treat Congenital Diaphragmatic Hernia

Antenatal stimulation of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and hypertension. Several evidences from the literature demonstrated a possible involvement of renin-angiotensin system (RAS) during fetal lung development. Thus, the expression pattern of renin, angiotensin-converting enzyme, angiotensinogen, type 1 (AT1) and type 2 (AT2) receptors of angiotensin II (ANGII) was assessed by immunohisto-chemistry throughout gestation, whereas the function of RAS in the fetal lung was evaluated using fetal rat lung explants. These were morphometrically analyzed and intracellular pathway alterations assessed by Western blot. In nitrofen-induced CDH model, pregnant rats were treated with saline or PD-123319. In pups, lung growth, protein/DNA ratio, radial saccular count, epithelial differentiation and lung maturation, vascular morphometry, right ventricular hypertrophy and overload molecular markers, gasometry and survival time were evaluated. Results demonstrated that all RAS components were constitutively expressed in the lung during gestation and that ANGII had a stimulatory effect on lung branching, mediated by AT1 receptor, through p44/42 and Akt phosphorylation. This stimulatory effect on lung growth was mimicked by AT2-antagonist (PD-123319) treatment. In vivo antenatal PD-123319 treatment increased lung growth, ameliorated indirect parameters of pulmonary hypertension, improved lung function and survival time in nonventilated CDH pups, without maternal or fetal deleterious effects. Therefore, this study demonstrated a local and physiologically active RAS during lung morphogenesis. Moreover, selective inhibition of AT2 receptor is presented as a putative antenatal therapy for CDH

Resumos concluídos - Neurociências

Resumos concluídos -  Neurociência

Proceedings Of The 23Rd Paediatric Rheumatology European Society Congress: Part Two

PubMe

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora

Outcomes in Newly Diagnosed Atrial Fibrillation and History of Acute Coronary Syndromes: Insights from GARFIELD-AF

BACKGROUND: Many patients with atrial fibrillation have concomitant coronary artery disease with or without acute coronary syndromes and are in need of additional antithrombotic therapy. There are few data on the long-term clinical outcome of atrial fibrillation patients with a history of acute coronary syndrome. This is a 2-year study of atrial fibrillation patients with or without a history of acute coronary syndromes