253 research outputs found

    The new wave of polish migration after EU enlargement - current state, determinants and outlook

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    Following Poland’s accession to the EU there has been a major change in outward migration patterns from Poland. In the last three years Poland has witnessed an increased outflow of workers, especially to Great Britain and Ireland, two countries that opened up their labour markets as early as in May 2004. By analyzing different sources of data we try to obtain a fairly consistent view of the scale of migration from Poland to these two countries and of the profile of Polish migrants with respect to such characteristics as age, education, jobs held in the country of immigration, earnings, intended length of stay and reasons for migration. In light of the theories of migration, empirical evidence as well as results of recent surveys of Poles working in Britain and Ireland, the wage-differential between Poland and the two destination countries of migration appears to be a valid explanation for the recent post-accession wave of migration. Given this result we run a simulation of development of wages in Poland, the UK and Ireland to find out if the ‘wage-differential’ motive for migration is likely to be influential in the coming years. We find that this motive is unlikely to lose significance, even despite the rapid growth of Polish wages in the last few months.international migration, determinants of migration, Poland, enlargement, European Union

    Identification and determination of ergot alkaloids in Morning Glory cultivars

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    Seeds of plants from Ipomoea genera contain numerous ergot alkaloids, including psychoactive ergine and ergometrine, and are often abused as so-called “legal highs.” In this work, an analytical method for determination of ergine and ergometrine, and identification of other alkaloids was developed, optimized, and validated. Three extraction techniques, ultrasound-assisted extraction in bath, or with sonotrode, and microwave-assisted extraction were evaluated, and it was concluded that ultrasonic bath is the most suitable technique for extraction of ergot alkaloids. The extraction method was later optimized using a Doehlert experimental design with response surface methodology and used together with the optimized LC-Q-TOF-MS method. The analytical procedure was validated in terms of recovery and matrix effect, repeatability, and intermediate precision. Limits of detection and quantification were 1.0 and 3.0 ng mL(–1), respectively, and were sufficient for determination of ergot alkaloids in Ipomoea seeds. The analysis revealed that from five kinds of seeds purchased from different vendors, only three contained ergot alkaloids. Concentration of alkaloids and their relative abundance was similar in samples representative for whole seeds packs; however, when single seeds were analyzed, significant discrepancies in ergine and ergometrine concentrations were detected. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00216-016-9322-5) contains supplementary material, which is available to authorized users

    Solid state diffusion

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    The workshop is composed of two main parts: the first part devoted to atomistic Monte Carlo simulations and the second part devoted to the Phase Field modelling. In each part a lecture will be accompanied by exercise activities

    The new wave of polish migration after EU enlargement - current state, determinants and outlook

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    Following Poland’s accession to the EU there has been a major change in outward migration patterns from Poland. In the last three years Poland has witnessed an increased outflow of workers, especially to Great Britain and Ireland, two countries that opened up their labour markets as early as in May 2004. By analyzing different sources of data we try to obtain a fairly consistent view of the scale of migration from Poland to these two countries and of the profile of Polish migrants with respect to such characteristics as age, education, jobs held in the country of immigration, earnings, intended length of stay and reasons for migration. In light of the theories of migration, empirical evidence as well as results of recent surveys of Poles working in Britain and Ireland, the wage-differential between Poland and the two destination countries of migration appears to be a valid explanation for the recent post-accession wave of migration. Given this result we run a simulation of development of wages in Poland, the UK and Ireland to find out if the ‘wage-differential’ motive for migration is likely to be influential in the coming years. We find that this motive is unlikely to lose significance, even despite the rapid growth of Polish wages in the last few months

    The new wave of polish migration after EU enlargement - current state, determinants and outlook

    Get PDF
    Following Poland’s accession to the EU there has been a major change in outward migration patterns from Poland. In the last three years Poland has witnessed an increased outflow of workers, especially to Great Britain and Ireland, two countries that opened up their labour markets as early as in May 2004. By analyzing different sources of data we try to obtain a fairly consistent view of the scale of migration from Poland to these two countries and of the profile of Polish migrants with respect to such characteristics as age, education, jobs held in the country of immigration, earnings, intended length of stay and reasons for migration. In light of the theories of migration, empirical evidence as well as results of recent surveys of Poles working in Britain and Ireland, the wage-differential between Poland and the two destination countries of migration appears to be a valid explanation for the recent post-accession wave of migration. Given this result we run a simulation of development of wages in Poland, the UK and Ireland to find out if the ‘wage-differential’ motive for migration is likely to be influential in the coming years. We find that this motive is unlikely to lose significance, even despite the rapid growth of Polish wages in the last few months

    Self-diffusion in a triple-defect A-B binary system : Monte Carlo simulation

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    In this comprehensive and detailed study, vacancy-mediated self-diffusion of A- and B-elements in triple-defect B2-ordered ASB1-S binaries is simulated by means of a kinetic Monte Carlo (KMC) algorithm involving atomic jumps to nearest-neighbour (nn) and next-nearest-neighbour (nnn) vacancies. The systems are modelled with an Ising-type Hamiltonian with nn and nnn pair interactions completed with migration barriers dependent on local configurations. Self-diffusion is simulated at equilibrium and temperature-dependent vacancy concentrations are generated by means of a Semi Grand Canonical MC (SGCMC) code. The KMC simulations reproduced the phenomena observed experimentally in Ni-Al intermetallics being typical representatives of the 'triple-defect' binaries. In particular, they yielded the characteristic ‘V’-shapes of the isothermal concentration dependencies of A- and B-atom diffusivities, as well as the strong enhancement of the B-atom diffusivity in B-rich systems. The atomistic origins of the phenomenon, as well as other features of the simulated self-diffusion such as temperature and composition dependences of tracer correlation factors and activation energies are analyzed in depth in terms of a number of nanoscopic parameters that are able to be tuned and monitored exclusively with atomistic simulations. The roles of equilibrium and kinetic factors in the generation of the observed features are clearly distinguished and elucidated

    Guidance document on Measurement Uncertainty for GMO Testing Laboratories 3rd Edition

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    This document provides guidance to GMO control laboratories on how to estimate measurement uncertainty (MU) associated with any GMO measurement result. Competent authorities have a responsibility to decide if a measurement result exceeds the legal threshold. Consequently control laboratories must estimate and report the MU of their measurement results. Quantitative polymerase chain reaction (qPCR) and digital polymerase chain reaction (dPCR) are the methods applied for the enforcement of EU law on GMO labelling. This document takes into account: current EU legislation, the availability of certified reference materials (CRMs) and validated methods, and the need for control laboratories which conduct measurements for the enforcement of EU legislation to be accredited according to ISO/IEC 17025. Based on these, two approaches for the estimation of MU for PCR measurement results are presented in this guidance document. References to alternative approaches are also provided.JRC.F.5-Food and Feed Complianc

    99mTc-EDDA/HYNIC-octreotate - a new radiotracer for detection and staging of NET. A case of metastatic duodenal carcinoid

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    Somatostatin receptor scintigraphy (SRS) has become a routine imaging method for the diagnostics of neuroendocrine tumours (NET). 99mTc-EDDA/HYNIC-octreotate (Polatom, Poland) is a new radiotracer with high affinity for SSTR2 and similar physiological biodistribution to 111In-Octreoscan. We present a case of a 47-year-old man with disseminated duodenal carcinoid. The patient had been operated due to the tumour mass detected in pancreatic head area. Histopathology revealed carcinoid of the duodenal wall with local lymph node and liver metastases. The patient was qualified for chemotherapy stopped due to severe leucopenia. 99mTc EDDA/HYNIC-octreotate scintigraphy was performed for staging and to determine SSTR status of the tumour before planned 90Y-DOTATATE therapy. The multiple metastatic lesions were detected all over the body. The high quality images with high target/non target ratio were obtained. 99mTc-MDP scintigraphy confirmed multiple bone metastases. On the basis of SRS result the patient was qualified for 90Y-DOTA-TATE therapy. In conclusion, 99mTc EDDA/HYNIC-octreotate can be regarded as a promising tracer for staging and to determine SSTR status of NET

    ^{99m}Tc-EDDA/HYNIC-octreotate : a new radiotracer for detection and staging of NET : a case of metastatic duodenal carcinoid

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    Somatostatin receptor scintigraphy (SRS) has become a routine imaging method for the diagnostics of neuroendocrine tumours (NET). 99mTc-EDDA/HYNIC-octreotate (Polatom, Poland) is a new radiotracer with high affinity for SSTR2 and similar physiological biodistribution to 111In-Octreoscan. We present a case of a 47-year-old man with disseminated duodenal carcinoid. The patient had been operated due to the tumour mass detected in pancreatic head area. Histopathology revealed carcinoid of the duodenal wall with local lymph node and liver metastases. The patient was qualified for chemotherapy stopped due to severe leucopenia. 99mTc EDDA/HYNIC-octreotate scintigraphy was performed for staging and to determine SSTR status of the tumour before planned 90Y-DOTATATE therapy. The multiple metastatic lesions were detected all over the body. The high quality images with high target/non target ratio were obtained. 99mTc-MDP scintigraphy confirmed multiple bone metastases. On the basis of SRS result the patient was qualified for 90Y-DOTA-TATE therapy. In conclusion, 99mTc EDDA/HYNIC-octreotate can be regarded as a promising tracer for staging and to determine SSTR status of NET
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