1,064 research outputs found
A perfect storm? The impact of COVID-19 on community-based conservation in Namibia
We report on a rapid survey of five communal-area conservancies in Namibia to understand initial impacts on community-based conservation of national and international policies for dealing with the COVID-19 pandemic. Namibia’s Community-Based Natural Resources Management (CBNRM) programme has been growing for over 30 years, with high economic reliance on tourism and conservation hunting. We review the interrelationships between COVID-19, CBNRM, tourism and hunting, and discuss our findings under eight interlocking themes: 1) disruption to management and regular operational processes of conservancies, including 2) effects on conservancy wildlife patrolling and monitoring; 3) losses of revenue and cash flow in conservancy business operations; 4) impacts on Joint-Venture Partnerships; 5) impacts on employment opportunities and local livelihoods; 6) effects on community development projects and social benefits, including 7) disruption to funded projects and programmes; and 8) lack of technical capacity regarding communication technologies and equipment. In our conclusion we discuss tensions between an assumption that normal business can or will be resumed, and calls for the COVID-19 pandemic to create an opportunity for global choices away from ‘business-as-normal’. It is too early to tell what mix of these perspectives will unfold. What is clear is that communal-area conservancies must derive benefits from conservation activities in their areas that are commensurate with their role as key actors in the conservation of Namibia’s valuable wildlife and landscapes
A Model of Habitability Within the Milky Way Galaxy
We present a model of the Galactic Habitable Zone (GHZ), described in terms
of the spatial and temporal dimensions of the Galaxy that may favour the
development of complex life. The Milky Way galaxy is modelled using a
computational approach by populating stars and their planetary systems on an
individual basis using Monte-Carlo methods. We begin with well-established
properties of the disk of the Milky Way, such as the stellar number density
distribution, the initial mass function, the star formation history, and the
metallicity gradient as a function of radial position and time. We vary some of
these properties, creating four models to test the sensitivity of our
assumptions. To assess habitability on the Galactic scale, we model supernova
rates, planet formation, and the time required for complex life to evolve. Our
study improves on other literature on the GHZ by populating stars on an
individual basis and by modelling SNII and SNIa sterilizations by selecting
their progenitors from within this preexisting stellar population. Furthermore,
we consider habitability on tidally locked and non-tidally locked planets
separately, and study habitability as a function of height above and below the
Galactic midplane. In the model that most accurately reproduces the properties
of the Galaxy, the results indicate that an individual SNIa is ~5.6 \times more
lethal than an individual SNII on average. In addition, we predict that ~1.2%
of all stars host a planet that may have been capable of supporting complex
life at some point in the history of the Galaxy. Of those stars with a
habitable planet, ~75% of planets are predicted to be in a tidally locked
configuration with their host star. The majority of these planets that may
support complex life are found towards the inner Galaxy, distributed within,
and significantly above and below, the Galactic midplane.Comment: Accepted for publication in Astrobiology. 40 pages, 12 figures, 3
table
Convolutamydine A and synthetic analogues have antinociceptive properties in mice
AbstractConvolutamydine A, an oxindole that originated from a marine bryozoan, has several biological effects. In this study, we aimed to investigate the antinociceptive effects of convolutamydine A and two new synthetic analogues.Convolutamydine A and the two analogues were given orally to assess their ability to induce antinociceptive effects. Formalin-induced licking response, acetic acid-induced contortions, and hot plate models were used to characterize the effects of convolutamydine A and its analogues.Convolutamydine A (4,6-bromo-3-(2-oxopropyl)-3-hydroxy-2-oxindole), compound 1 (3-(2-oxopropyl)-3-hydroxy-2-oxindole), and compound 2 (5-bromo-3-(2-oxopropyl)-3-hydroxy-2-oxindole) caused peripheral antinociceptive and anti-inflammatory effects in the acetic acid-induced contortions and the formalin-induced licking models. Supraspinal effects were also observed in the hot plate model and were similar to those obtained with morphine. The peripheral effects were not mediated by the cholinergic or opioid systems. The antinociceptive effects of convolutamydine A seem to be mediated by all three systems (cholinergic, opioid, and nitric oxide systems), and the mechanism of action of compounds 1 and 2 involved cholinergic and nitric oxide-mediated mechanisms. Convolutamydine A and its analogues (compounds 1 and 2) showed good antinociceptive ability after systemic administration in acute pain models. The antinociceptive action mediated by cholinergic, opioid, and nitric oxide systems could explain why convolutamydine A, compound 1, and compound 2 retained their antinociceptive effects. The doses used were similar to the doses of morphine and were much lower than that of acetylsalicylic acid, the classical analgesic and anti-inflammatory drug.In conclusion, convolutamydine A and the two analogues demonstrated antinociceptive effects comparable to morphine's effects
Comparing automated surveillance systems for detection of pathogen-related clusters in healthcare settings
BACKGROUND: Detection of pathogen-related clusters within a hospital is key to early intervention to prevent onward transmission. Various automated surveillance methods for outbreak detection have been implemented in hospital settings. However, direct comparison is difficult due to heterogenicity of data sources and methodologies. In the hospital setting, we assess the performance of three different methods for identifying microbiological clusters when applied to various pathogens with distinct occurrence patterns. METHODS: In this retrospective cohort study we use WHONET-SaTScan, CLAR (CLuster AleRt system) and our currently used percentile-based system (P75) for the means of cluster detection. The three methods are applied to the same data curated from 1st January 2014 to 31st December 2021 from a tertiary care hospital. We show the results for the following case studies: the introduction of a new pathogen with subsequent endemicity, an endemic species, rising levels of an endemic organism, and a sporadically occurring species. RESULTS: All three cluster detection methods showed congruence only in endemic organisms. However, there was a paucity of alerts from WHONET-SaTScan (n = 9) compared to CLAR (n = 319) and the P75 system (n = 472). WHONET-SaTScan did not pick up smaller variations in baseline numbers of endemic organisms as well as sporadic organisms as compared to CLAR and the P75 system. CLAR and the P75 system revealed congruence in alerts for both endemic and sporadic organisms. CONCLUSIONS: Use of statistically based automated cluster alert systems (such as CLAR and WHONET-Satscan) are comparable to rule-based alert systems only for endemic pathogens. For sporadic pathogens WHONET-SaTScan returned fewer alerts compared to rule-based alert systems. Further work is required regarding clinical relevance, timelines of cluster alerts and implementation
Noncommutative quantum mechanics and Bohm's ontological interpretation
We carry out an investigation into the possibility of developing a Bohmian
interpretation based on the continuous motion of point particles for
noncommutative quantum mechanics. The conditions for such an interpretation to
be consistent are determined, and the implications of its adoption for
noncommutativity are discussed. A Bohmian analysis of the noncommutative
harmonic oscillator is carried out in detail. By studying the particle motion
in the oscillator orbits, we show that small-scale physics can have influence
at large scales, something similar to the IR-UV mixing
Realistic Equations of State for the Primeval Universe
Early universe equations of state including realistic interactions between
constituents are built up. Under certain reasonable assumptions, these
equations are able to generate an inflationary regime prior to the
nucleosynthesis period. The resulting accelerated expansion is intense enough
to solve the flatness and horizon problems. In the cases of curvature parameter
\kappa equal to 0 or +1, the model is able to avoid the initial singularity and
offers a natural explanation for why the universe is in expansion.Comment: 32 pages, 5 figures. Citations added in this version. Accepted EPJ
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Being fluent and keeping looking
The complexities of the many concepts and models around information literacy are considered, and some personal views given as to how they may best be clarified, both theoretically and practically. A slightly adapted idea of the concept of information fluency can serve as a main general purpose for the promotion of information literacy, expressed as a more specific meta-model for the prevailing technological environment, and as still more specific components for a particular context. The focus of this relatively stable general formulation is on understanding, rather than skills or competences. It can incorporate the need for education, advice and counseling, as well as information provision, and with domain-specific literacies, as well as supporting personal information literacy
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