Leptogenesis from oscillations and dark matter

An extension of the Standard Model with Majorana singlet fermions in the 1-100 GeV range can give rise to a baryon asymmetry at freeze-in via the CP-violating oscillations of these neutrinos: this is the well known ARS mechanism. In this paper we consider possible extensions of the minimal ARS scenario that can account not only for successful leptogenesis but also explain other open problems such as dark matter. We find that an extension in the form of a weakly coupled B-L gauge boson, an invisible QCD axion model, and the singlet majoron model can simultaneously account for dark matter and the baryon asymmetry.Comment: A relevant previously neglected process has been included, conclusions mostly unchanged. Matches published versio

El català uneix els ports de Balears, Tarragona i Barcelona per mitjà de les noves tecnologies

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Leptogenesis in GeV-scale seesaw models

We revisit the production of leptonic asymmetries in minimal extensions of the Standard Model that can explain neutrino masses, involving extra singlets with Majorana masses in the GeV scale. We study the quantum kinetic equations both analytically, via a perturbative expansion up to third order in the mixing angles, and numerically. The analytical solution allows us to identify the relevant CP invariants, and simplifies the exploration of the parameter space. We find that sizeable lepton asymmetries are compatible with non-degenerate neutrino masses and measurable active-sterile mixings

Characterization of the Use of Emergency Contraception from Sentinel Pharmacies in a Region of Southern Europe

Numerous studies have been published suggesting that emergency contraception (EC) is used repeatedly, but a lack of information regarding the profile of users makes it difficult to evaluate actual consumer habits. The aim of this study was to obtain information regarding the profile of users who obtain EC and other factors that might play a role, and to provide criteria to evaluate and improve the strategies of current contraceptive programs. This was an observational one-year study based on surveillance data on the provision of EC to women of reproductive age in 60 community pharmacies in Catalonia, Spain. In total, 941 notifications of dispensation of EC in Catalonia were received. A total of 44.2% of users said it was not the first time that they had taken the medication (repeat user). The percentage of users who used condoms was lower in repeat users compared to first-time users (56.7% vs. 64.4%, p < 0.05). A total of 25.7% of users stated that they did not use any barrier contraceptive method. The use of natural methods in repeat users was 53.8% in the subgroup who requested the medication after 48 h, significantly higher than in users who obtained the medication within the first 24 h (p < 0.05). A high percentage of repeat users with risky sexual behaviors were detected, suggesting that new measures must be implemented to provide information for this method, together with educational and preventive strategies

Influenza syndromic surveillance based on sentinel pharmacies in Catalonia (Spain) in 2017-2020

Objective: To analyse influenza surveillance data obtained from sentinel pharmacies of Catalonia, Spain, in 2017−18, 2018−19 and 2019-20 influenza seasons. Methods: Influenza surveillance information was collected from a representative sample of community pharmacies of Catalonia. Influenza-like cases were identified based on the ECDC criteria.The Chi-square test and Odds ratios were used to compare percentages between different population groups, with a p <0.05 considered as statistically significant. The screening method was used to assess influenza vaccination effectiveness. The moving epidemic method (MEM) was used to assess influenza epidemics in the three influenza seasons. Results: A total of 836, 1,000 and 587 influenza-like cases were reported in 2017−18, 2018−19 and 2019−20. Sentinel pharmacies dispended medications to 94-98% of patients. Paracetamol, cough medication, ibuprofen and antihistamines were dispended to more than 25% of patients. Dispensation of antibiotics decreased by 57% from 2017-18 to 2019-20 (OR = 0.45, 95% CI: 0.28-0.74, p < 0.001). Physicians prescribed medications to 30-38% of influenza-like patients. The influenza vaccination effectiveness in individuals aged 65 or more years was 51.4% (95% CI: 41.9−60.7) in 2018-19 and 67% (95% CI: 53.4−79.8) in 2019-20 influenza seasons. Influenza epidemics occurred from week 50 of 2017 to week 7 of 2018; from week 51 of 2017 to week 8 of 2019; and from week 2 to week 7 of 2020. Conclusion: The influenza surveillance system based on sentinel pharmacies provided consistent information on the influenza epidemic, influenza morbidity not assisted in health centres and medications used to treat influenza-like cases during 2017−2019

Decision-making tool for the selection of priority areas for building rehabilitation in Barcelona

The promotion of rehabilitation is an urgent necessity in today’s consolidated cities, both due to the need to update their buildings to achieve habitability and safety standards that are required nowadays, as well as to stop the deterioration of buildings in vulnerable environments, where paradoxically the obtainment of economic resources to invest in building maintenance and upgrade is scarcer. Decision making on the delimitation of areas in which the need to invest is higher is extremely complex and often relies on large secondary data studies that are contrasted with local stakeholders’ intuition and knowledge on the ground. Usually, rehabilitation aids are directed to relatively large areas, where a certain need may be found. However, these areas are often excessively wide and specific needs that would require special focus can be diluted in the whole. The current trend of area-based and site-specific rehabilitation programs calls for precise and focused data studies and methodologies. The research presented here provides a methodology for the selection of priority areas to promote rehabilitation in the context of Barcelona’s vulnerable neighborhoods. The selection methodology combines primary and secondary data with a very high level of disaggregation that identifies where the needs are greatest, and it also provides a tool that is still based on primary disaggregated data for the delimitation of areas. The results obtained highlight specific priority areas such as parts of the Raval, Carmel and Besòs-Maresme neighborhoods within larger zones that had been previously defined as vulnerable. The proposed methodology seeks to provide tools to foster evidence-based decision making, thus improving both the understanding of reality and its spatial distribution through data mining techniques and data visualization.Postprint (author's final draft

Evaluation of Medicine Abuse Trends in Community Pharmacies: The Medicine Abuse Observatory (MAO) in a Region of Southern Europe

The misuse of medicines is a global public health concern that needs to be taken into consideration and requires actions across all government sectors and society. The aim of this study is to identify trends of drug abuse in Catalonia, a region of Spain located in the South of Europe. For this purpose, a questionnaire-based detection tool was created and implemented in 60 community pharmacies. Out of 548 questionnaires (98.4%), 64.2% of participants were men and the highest age proportion was 25-35 years (31.4%). Potential drug abuse was the highest in urban pharmacies (84.9%). The main drug class involved were benzodiazepines (31.8%), codeine (19.3%), tramadol (7.5%), methylphenidate (5.8%), gabapentinoids (5.8%), cycloplegic drops (4.4%), z-drugs (2.6%), piracetam (2.2%), dextromethorphan (1.6%) and clomethiazole (1.1%). The majority of drugs were requested without prescription (58.6%) and through probably forged prescriptions (23.7%). Slightly less than half (49.8%) of the patients request frequently to the pharmacist, especially in rural and mountain pharmacies (73.3% and 88.5%, respectively). A small proportion (10.8%) were requested with intimidation. Pharmacists only supplied in 21.7% of the cases. This study has demonstrated the suitability of the new detection system, being a useful approach to replicate in other locations with similar needs

El papel de los farmacéuticos comunitarios en la prevención y control de la Covid-19 en Cataluña

Introducción: En las últimas décadas, tanto la farmacia como el farmacéutico han estado en constante evolución, siendo fundamentales en el control de enfermedades infecciosas. Los objetivos de este artículo son mostrar el papel de los farmacéuticos comunitarios en el control de la COVID-19 y conocer la percepción que tienen sobre su papel en el control de esta pandemia. Métodos: Se realizó y envió una encuesta a 8556 farmacéuticos comunitarios colegiados en Cataluña, donde se les preguntaba por su opinión y la percepción que tenían de su rol en distintas actividades de control de la COVID-19. Se realizó un análisis bivariante y descriptivo de las diferentes variables de la encuesta de manera global y estratificado por grupos de edad (60 años) y por tipo de farmacia (urbana vs otras). Resultados: La tasa de respuesta de la encuesta fue del 14,63% (1253). A pesar de la percepción positiva que tienen los farmacéuticos sobre su rol en la pandemia, el 90,9% de los encuestados considera que la Administración Sanitaria no contó mucho con las farmacias al inicio de esta. Se han encontrado diferencias estadísticamente significativas en determinados aspectos, como por ejemplo en la percepción que el farmacéutico tiene sobre el nivel de información del usuario, o en la frecuencia de encuentros con negacionistas, ambos hechos relacionados con la edad del farmacéutico (p=0,047 y p=0,001 respectivamente). Conclusiones: Las farmacias son establecimientos sanitarios estratégicamente posicionados para realizar actividades de salud pública para colaborar en el control de pandemias. Por lo que el farmacéutico comunitario, en tanto que profesional de la salud, debe ser considerado una pieza más del engranaje para mejorar la eficiencia del sistema sanitario

El papel de los farmacéuticos comunitarios en la prevención y control de la Covid-19 en Cataluña

Introducción: En las últimas décadas, tanto la farmacia como el farmacéutico han estado en constante evolución, siendo fundamentales en el control de enfermedades infecciosas. Los objetivos de este artículo son mostrar el papel de los farmacéuticos comunitarios en el control de la COVID-19 y conocer la percepción que tienen sobre su papel en el control de esta pandemia. Métodos: Se realizó y envió una encuesta a 8556 farmacéuticos comunitarios colegiados en Cataluña, donde se les preguntaba por su opinión y la percepción que tenían de su rol en distintas actividades de control de la COVID-19. Se realizó un análisis bivariante y descriptivo de las diferentes variables de la encuesta de manera global y estratificado por grupos de edad (60 años) y por tipo de farmacia (urbana vs otras). Resultados: La tasa de respuesta de la encuesta fue del 14,63% (1253). A pesar de la percepción positiva que tienen los farmacéuticos sobre su rol en la pandemia, el 90,9% de los encuestados considera que la Administración Sanitaria no contó mucho con las farmacias al inicio de esta. Se han encontrado diferencias estadísticamente significativas en determinados aspectos, como por ejemplo en la percepción que el farmacéutico tiene sobre el nivel de información del usuario, o en la frecuencia de encuentros con negacionistas, ambos hechos relacionados con la edad del farmacéutico (p=0,047 y p=0,001 respectivamente). Conclusiones: Las farmacias son establecimientos sanitarios estratégicamente posicionados para realizar actividades de salud pública para colaborar en el control de pandemias. Por lo que el farmacéutico comunitario, en tanto que profesional de la salud, debe ser considerado una pieza más del engranaje para mejorar la eficiencia del sistema sanitario

Summary report of MINSIS workshop in Madrid

Recent developments on tau detection technologies and the construction of high intensity neutrino beams open the possibility of a high precision search for non-standard {\mu} - {\tau} flavour transition with neutrinos at short distances. The MINSIS - Main Injector Non-Standard Interaction Search- is a proposal under discussion to realize such precision measurement. This document contains the proceedings of the workshop which took place on 10-11 December 2009 in Madrid to discuss both the physics reach as well as the experimental requirements for this proposal.Comment: Proceedings of the MINSIS Workshop, Dec 10-11, 2009 in Madrid. 15 pages late