Real-time antenna fault diagnosis experiments at DSS 13

Experimental results obtained when a previously described fault diagnosis system was run online in real time at the 34-m beam waveguide antenna at Deep Space Station (DSS) 13 are described. Experimental conditions and the quality of results are described. A neural network model and a maximum-likelihood Gaussian classifier are compared with and without a Markov component to model temporal context. At the rate of a state update every 6.4 seconds, over a period of roughly 1 hour, the neural-Markov system had zero errors (incorrect state estimates) while monitoring both faulty and normal operations. The overall results indicate that the neural-Markov combination is the most accurate model and has significant practical potential

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis

The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium. The molecular basis and functional consequences of virus conformational dynamics are poorly understood. Here, we identified a single mutation at residue 198 (T198F) of the West Nile virus (WNV) E protein domain I-II hinge that regulates virus breathing. The T198F mutation resulted in a ~70-fold increase in sensitivity to neutralization by a monoclonal antibody targeting a cryptic epitope in the fusion loop. Increased exposure of this otherwise poorly accessible fusion loop epitope was accompanied by reduced virus stability in solution at physiological temperatures. Introduction of a mutation at the analogous residue of dengue virus (DENV), but not Zika virus (ZIKV), E protein also increased accessibility of the cryptic fusion loop epitope and decreased virus stability in solution, suggesting that this residue modulates the structural ensembles sampled by distinct flaviviruses at equilibrium in a context dependent manner. Although the T198F mutation did not substantially impair WNV growth kinetics in vitro, studies in mice revealed attenuation of WNV T198F infection. Overall, our study provides insight into the molecular basis and the in vitro and in vivo consequences of flavivirus breathing

Ecohydrologic Impacts of Rangeland Fire on Runoff and Erosion: A Literature Synthesis

Fire can dramatically influence rangeland hydrology and erosion by altering ecohydrologic relationships. This synthesis presents an ecohydrologic perspective on the effects of fire on rangeland runoff and erosion through a review of scientific literature spanning many decades. The objectives are: (1) to introduce rangeland hydrology and erosion concepts necessary for understanding hydrologic impacts of fire; (2) to describe how climate, vegetation, and soils affect rangeland hydrology and erosion; and (3) to use examples from literature to illustrate how fire interacts with key ecohydrologic relationships. The synthesis is intended to provide a useful reference and conceptual framework for understanding and evaluating impacts of fire on rangeland runoff and erosion

Salute The Flag : March and Two Step

https://digitalcommons.library.umaine.edu/mmb-ps/2482/thumbnail.jp

Dissipation in graphene and nanotube resonators

Different damping mechanisms in graphene nanoresonators are studied: charges in the substrate, ohmic losses in the substrate and the graphene sheet, breaking and healing of surface bonds (Velcro effect), two level systems, attachment losses, and thermoelastic losses. We find that, for realistic structures and contrary to semiconductor resonators, dissipation is dominated by ohmic losses in the graphene layer and metallic gate. An extension of this study to carbon nanotube-based resonators is presented.Comment: Published version with updated reference