23 research outputs found

    The Role of Endothelin-1 and Endothelin Receptor Antagonists in Inflammatory Response and Sepsis

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    CFD simulations of blood flow through abdominal part of aorta

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    The aim of this research was to show superiority of using real geometries in simulations of blood fl ow through cardiovascular system. Our model compared blood fl ow through an abdominal part of aorta reconstructed with a use of data from an AngioTK research with the 3DDoctor software to geometries with the same diameters at inlet and outlet as mention before but created only with the Gambit 2.2.30 software without data from AngioTK. Blood fl ow simulations were prepared with the Fluent 6.2.16 software. Calculations of fl ow through a real geometry allows to obtain realistic results of values connected with process of blood fl ow. Results showed that calculations blood fl ow through a virtual geometry lasted two times longer than for a real geometry. Mesh for a real geometry consist about 600.000 elements and for a virtual geometry about 900.000 elements. Wall shear stress and blood velocity was higher for a real geometry and closer to that in human organism. It was shown that calculating a virtual geometry vessel was to big simplifi cation when investigating blood fl ow through a vessel. Application of mathematical models based on real geometries gives more realistic results than artifi cial geometries. Virtual models have lots of simplifi cations which results are far away from expectations. Simplifi cations depend on the model that is used
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