Neutrino CP violating parameters from nontrivial quark-lepton correlation: a S3xGUT model

We investigate the prediction on the lepton phases in theories with a non trivial correlation between quark (CKM) and lepton (PMNS) mixing matrices. We show that the actual evidence, under the only assumption that the correlation matrix $V^M$ product of $CKM$ and $PMNS$ has a zero in the entry $(1,3)$, gives us a prediction for the three CP-violating invariants $J$, $S_1$, and $S_2$. A better determination of the lepton mixing angles will give a strong prediction of the CP-violating invariants in the lepton sector. These will be tested in the next generation experiments. To clarify how our prediction works, we show how a model based on a Grand Unified Theory and the permutation flavor symmetry $S_3$ predicts $V^M_{13}=0$.Comment: 7 pages, 3 figures. V2: new figure adde

Embedding A4 into left-right flavor symmetry: Tribimaximal neutrino mixing and fermion hierarchy

We address two fundamental aspects of flavor physics: the mass hierarchy and the large lepton mixing angles. On one side, left-right flavor symmetry realizes the democratic mass matrix patterns and explains why one family is much heavier than the others. On the other side, discrete flavor symmetry such as A4 leads to the observed tribimaximal mixing for the leptons. We show that, by explicitly breaking the left-right flavor symmetry into the diagonal A4, it is possible to explain both the observed charged fermion mass hierarchies and quark and lepton mixing angles. In particular we predict a heavy 3rd family, the tribimaximal mixing for the leptons, and we suggest a possible origin of the Cabibbo and other mixing angles for the quarks.Comment: 9 pages, uses revtex4 and axodraw.st

Vacuum Condensates and Dynamical Mass Generation in Euclidean Yang-Mills Theories

Vacuum condensates of dimension two and their relevance for the dynamical mass generation for gluons in Yang-Mills theories are discussedComment: Talk given at the International Conference on Color Confinement and Hadrons in Quantum Chromodynamics, Confinement 2003, TITech and RIKEN, Tokyo, Japan, July 21-24, 200

A SUSY SU(5) Grand Unified Model of Tri-Bimaximal Mixing from A4

We discuss a grand unified model based on SUSY SU(5) in extra dimensions and on the flavour group A4xU(1) which, besides reproducing tri-bimaximal mixing for neutrinos with the accuracy required by the data, also leads to a natural description of the observed pattern of quark masses and mixings.Comment: 19 page

Defining routine fatigue care in Multiple Sclerosis in the United Kingdom: What treatments are offered and who gets them?

Background Fatigue is common and disabling in Multiple Sclerosis (MS). A recent meta-analytic systematic review reported 113 trials of exercise and behavioural interventions for fatigue, yet patients consistently describe fatigue being under-treated. The extent of the research-to-practice gap is yet to be documented. Objective To describe what fatigue treatments people with MS (pwMS) in the United Kingdom (UK) have been offered. Methods A cross-sectional survey of pwMS on the UK MS Register (UKMSR). Data on fatigue treatments offered were collected using an online questionnaire developed with patient input and summarised using descriptive statistics. Sociodemographic, MS-related, and psychological factors associated with treatment offered were evaluated using a logistic regression model. Results 4,367 respondents completed the survey, 90.3% reported experiencing fatigue. Of these, 30.8% reported having been offered at least one type of pharmacological/non-pharmacological treatment for fatigue. Pharmacological treatments were more commonly offered (22.4%) compared to non-pharmacological treatments (12.6%; 2.9% exercise and 5.9% behavioural therapy). In the logistic regression model, older age, working, shorter time since MS diagnosis, and lower fatigue were associated with lower odds of having been offered treatment for fatigue. Conclusion This study accentuates the extent of the unmet need for fatigue treatment in MS in the UK. </jats:sec