"Análisis con Google Trends y Our World in Data sobre la salud mental mundial en el contexto de la pandemia por covid-19"

"Introducción: Durante la pandemia de la covid-19 los servicios de salud mental no pudieron darse abasto debido a la gran demanda, por lo cual, muchas personas optaron por buscar información por Internet que las pudiera ayudar a sobrellevar el proceso psicológico que estaban experimentando en ese momento. Objetivo: Caracterizar la tendencia mundial de búsqueda del término «psiquiatría» en el contexto de covid-19 mediante Google Trends y Our World in Data. Métodos: Estudio descriptivo-transversal sobre las tendencias mundiales de búsquedas de información sobre psiquiatría en el contexto de la covid-19 bajo los términos «psiquiatría», «depresión», «ansiedad», «estrés», «insomnio» y «suicidio» en la categoría de salud en el periodo del 2020-2021. Se generaron gráficos temporales. Resultados: El término «psiquiatría» se mantuvo con un volumen relativo de búsqueda elevado y constante (entre 60 y 90), con una búsqueda importante y paulatina en el mes de abril. El volumen relativo de búsquedas de «depresión», «ansiedad» y «estrés» se mantuvieron constantes con ciertas fluctuaciones no significativas a lo largo del periodo 2020-2021. El término «insomnio» tuvo una predominancia entre enero y junio del 2020, fue decayendo poco a poco desde abril y se mantuvo constante hasta octubre del 2021. Finalmente, el término «suicidio» obtuvo un VRB fluctuante entre 60 y 100 durante este periodo. Conclusiones: Durante el periodo de estudio los temas relacionados con la salud mental y la especialidad de psiquiatría se mantuvieron constantes, con algunas variaciones fluctuantes pero no llamativas.

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis

Patients with multiple sclerosis (MS) suffer with age an early immunosenescence process, which influence the treatment response and increase the risk of infections. We explored whether lipid-specific oligoclonal IgM bands (LS-OCMB) associated with highly inflammatory MS modify the immunological profile induced by age in MS. This cross-sectional study included 263 MS patients who were classified according to the presence (M+, n=72) and absence (M-, n=191) of LS-OCMB. CSF cellular subsets and molecules implicated in immunosenescence were explored. In M- patients, aging induced remarkable decreases in absolute CSF counts of CD4+ and CD8+ T lymphocytes, including Th1 and Th17 cells, and of B cells, including those secreting TNF-alpha. It also increased serum anti-CMV IgG antibody titers (indicative of immunosenescence) and CSF CHI3L1 levels (related to astrocyte activation). In contrast, M+ patients showed an age-associated increase of TIM-3 (a biomarker of T cell exhaustion) and increased values of CHI3L1, independently of age. Finally, in both groups, age induced an increase in CSF levels of PD-L1 (an inductor of T cell tolerance) and activin A (part of the senescence-associated secretome and related to inflammaging). These changes were independent of the disease duration. Finally, this resulted in augmented disability. In summary, all MS patients experience with age a modest induction of T-cell tolerance and an activation of the innate immunity, resulting in increased disability. Additionally, M- patients show clear decreases in CSF lymphocyte numbers, which could increase the risk of infections. Thus, age and immunological status are important for tailoring effective therapies in MS.This work was supported by grants FIS-PI15/00513, FIS-PI18/00572 and RD16/0015/0001 from the Instituto de Salud Carlos III. Ministerio de Ciencia e Innovación, Spain and FEDER: "Una manera de hacer Europa"

La Cueva de El Sidrón (Piloña Asturias)

Estado de las excavaciones y estudios en la Cueva de El Sidrón (PIloña, Asturias)

Comunidades, territorios y turismo en América Latina

Este libro es una suerte de regreso al futuro en la medida que intenta explicar la historia reciente del desarrollo turístico como parte de los males del capitalismo neoliberal globalizado, y al mismo tiempo tornar palpable las ventajas y oportunidades de ese otro turismo, enraizado en los paisajes naturales y culturales de las comunidades locales

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Innovación en las enseñanzas universitarias: experiencias presentadas en las III Jornadas de Innovación Educativa de la ULL

En este libro se recoge un conjunto de experiencias de innovación educativa desarrolladas en la ULL en el curso 2011-12. Se abordan distintos ámbitos y ramas del conocimiento, y ocupan temáticas variadas que han sido desarrolladas con rigor, y con un claro potencial para su extrapolación a efectos de la mejora educativa en el ámbito universitario. Esta publicación constituye una primera edición de una serie que irá recogiendo las experiencias de innovación educativa de la ULL. Este es un paso relevante para su impulso en nuestra institución, como lo es el de su vinculación con la investigación educativa, para potenciar su publicación en las revistas científicas en este ámbito cada vez más pujante y relevante para las universidades. Sobre todo representan el deseo y el compromiso del profesorado de la ULL para la mejora del proceso educativo mediante la investigación, la evaluación y la reflexión compartida de nuestras prácticas y planteamientos docentes

Incorporating the Concept of Flexible Operation in the Design of Solar Collector Fields for Industrial Applications

This work introduces the concept of flexible operation in the design of solar thermal utility systems for low temperature processes. The design objectives are: (a) The supply of the thermal needs of the process (heat duty and minimum required temperature), and (b) the maximization of the operating time during the day. The approach shows how the network structure is defined by adjusting the mass flow rate and the inlet temperature of the working fluid to achieve the smallest collector surface area. This work emphasizes the need to specify the solar network structure, which is comprised of two main elements: The number of lines in parallel and the number of collectors in series in each line. The former of these two design specifications is related to the heat load that the system will supply, while the latter is directly related to the delivery temperature. A stepwise design approach is demonstrated using two case studies where it is shown that the detailed design of the solar collector network structure is fundamental for a successful thermal integration with minimum investment. In this paper, the design methodology is based on flat-plate solar collectors, but it can be extended to any other type of low temperature solar technology

Associations between Chronotype, Adherence to the Mediterranean Diet and Sexual Opinion among University Students.

Abstract: A person’s chronotype determines different habits, among which are eating and physical activity. Furthermore, at the university stage, social and organisational factors have a direct effect on students’ daily attitudes and habits. Adherence to the Mediterranean diet is linked to better sleep quality and less social jet lag, but association with chronotype or sexual opinion remains unclear. The aim of this study was to assess the associations between chronotype, adherence to the Mediterranean Diet, and sexual opinion. A multicentre observational study enrolled 457 students, from the University of Castilla-La Mancha and the University of Cordoba. Sociodemographic data and adherence to the Mediterranean diet, chronotype, physical activity, and sexual opinion were collected with validated questionnaires. The study period was from December 2017 to January 2018. Our results reported that students with an evening chronotype (E-type), with evening preferences, had a lower adherence to the Mediterranean diet and showed a higher tendency towards erotophilia. E-type students reported a significantly lower intake of fruits, vegetables, pulses, cereals, and olive oil, and higher breakfast skipping. Therefore, among the measures to promote healthy habits (obesity prevention, sexual education, socialisation, etc.), chronotype and an analysis of the impact of the schedules established by the universities must be considered

Risky Behaviours of Spanish University Students: Association with Mediterranean Diet, Sexual Attitude and Chronotype.

Abstract: The most common drugs that are consumed by young people are alcohol and tobacco, which are especially prevalent in universities. These risk behaviours can be determined by a series of intrinsic and extrinsic factors. The aim of this study was to evaluate the consumption of alcohol and tobacco by Spanish university students and the relationship between the Mediterranean diet, sexual attitudes and opinions, and chronotype. A multicentre observational study enrolled 457 students from two public universities in Spain. The study period was from December 2017 to January 2018. The majority of the participants consumed alcohol (90.2%), tobacco consumption was low (27.2%), with a high percentage of students (78.6%) having a low dependence on nicotine. The surveyed students demonstrated a high adherence to the Mediterranean diet, which was shown to be associated with less risky alcohol consumption. The Mediterranean diet is a part of healthy lifestyle, and avoiding heavy drinking results in the intention to maintain such a lifestyle. In addition, unhealthy eating habits (skipping breakfast, eating sweets and pastries daily, and fast-food consumption) had a tendency to induce risky alcohol consumption. Therefore, to promote healthy lifestyle habits, it is considered important to establish programs that promote healthy diets in university settings and to evaluate them periodically