2,302 research outputs found
OECD reviews of higher education in regional and city development, State of Victoria, Australia
With more than 5.3 million inhabitants Victoria is the second most populous state in Australia. Once a manufacturing economy, Victoria is now transforming itself into a service and innovation-based economy. Currently, the largest sectors are education services and tourism. In terms of social structure, Victoria is characterised by a large migrant population, 24% of population were born overseas and 44% were either born overseas or have a parent who was born overseas. About 70% of the population resides in Melbourne. Victoria faces a number of challenges, ranging from an ageing population and skills shortages to drought and climate change and increased risk of natural disasters. Rapid population growth, 2% annually, has implications for service delivery and uneven development as well as regional disparities. There are barriers to connectivity in terms of transport and infrastructure, and a high degree of inter-institutional competition in tertiary education sector. The business structure in Victoria includes some highly innovative activities such as in biotechnology, but other sectors, especially those with high number of small and medium-sized enterprises, are lagging behind. Most of the larger manufacturing enterprises are externally controlled and there is uncertainty over the long term investments they will make in the state, as well as the place of Victoria in the global production networks
One-year follow-up of family versus child CBT for anxiety disorders: Exploring the roles of child age and parental intrusiveness.
ObjectiveTo compare the relative long-term benefit of family-focused cognitive behavioral therapy (FCBT) and child-focused cognitive behavioral therapy (CCBT) for child anxiety disorders at a 1-year follow-up.MethodThirty-five children (6-13 years old) randomly assigned to 12-16 sessions of family-focused CBT (FCBT) or child-focused CBT (CCBT) participated in a 1-year follow-up assessment. Independent evaluators, parents, and children rated anxiety and parental intrusiveness. All were blind to treatment condition and study hypotheses.ResultsChildren assigned to FCBT had lower anxiety scores than children assigned to CCBT on follow-up diagnostician- and parent-report scores, but not child-report scores. Exploratory analyses suggested the advantage of FCBT over CCBT may have been evident more for early adolescents than for younger children and that reductions in parental intrusiveness may have mediated the treatment effect.ConclusionFCBT may yield a stronger treatment effect than CCBT that lasts for at least 1 year, although the lack of consistency across informants necessitates a circumspect view of the findings. The potential moderating and mediating effects considered in this study offer interesting avenues for further study
Cadmium and arsenic-induced-stress differentially modulates Arabidopsis root architecture, peroxisome distribution, enzymatic activities and their nitric oxide content
In plant cells, cadmium (Cd) and arsenic (As) exert toxicity mainly by inducing oxidative stress through an imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), and their detoxification. Nitric oxide (NO) is a RNS acting as signalling molecule coordinating plant development and stress responses, but also as oxidative stress inducer, depending on its cellular concentration. Peroxisomes are versatile organelles involved in plant metabolism and signalling, with a role in cellular redox balance thanks to their antioxidant enzymes, and their RNS (mainly NO) and ROS. This study analysed Cd or As effects on peroxisomes, and NO production and distribution in the root system, including primary root (PR) and lateral roots (LRs). Arabidopsis thaliana wild-type and transgenic plants enabling peroxisomes to be visualized in vivo, through the expression of the 35S-cyan fluorescent protein fused to the peroxisomal targeting signal1 (PTS1) were used. Peroxisomal enzymatic activities including the antioxidant catalase, the H2O2-generating glycolate oxidase, and the hydroxypyruvate reductase, and root system morphology were also evaluated under Cd/As exposure. Results showed that Cd and As differently modulate these activities, however, catalase activity was inhibited by both. Moreover, Arabidopsis root system was altered, with the pollutants differently affecting PR growth, but similarly enhancing LR formation. Only in the PR apex, and not in LR one, Cd more than As caused significant changes in peroxisome distribution, size, and in peroxisomal NO content. By contrast, neither pollutant caused significant changes in peroxisomes size and peroxisomal NO content in the LR apex
Occupational Sitting and Physical Activity Among University Employees
International Journal of Exercise Science 7(4) : 295-301, 2014. The prevalence of overweight and obese in the U.S. has been thoroughly documented. With the advent of inactivity physiology research and the subsequent interest in sedentary behavior, the work environment has come under closer scrutiny as a potential opportunity to reverse inactivity. Therefore, the purpose of this study was to determine the sitting and physical activity (PA) habits among different classifications of university employees. University employees (n=625) completed an online survey based on the Occupational Sitting and Physical Activity Questionnaire (OSPAQ). Participants were instructed to describe time spent sitting, standing, walking, and in heavy physical labor during the last seven days, along with the number of breaks from sitting taken per hour. To establish habitual patterns of PA outside of work, employees recalled their participation in structured PA in the past seven days. Prior to data analysis, employees were categorized as Administration, Faculty, Staff, or Facilities Management. Statistically significant differences were found among employee classifications for min sit/d, p\u3c.001; min stand/d, p\u3c.001; min walk/d, p\u3c.001; and min heavy labor/d, p\u3c.001. No significant differences were found for breaks/h from sitting, p=.259 or participation in structured PA, p=. 33. With the exception of facilities management workers, university employees spent 75% of their workday seated. In conjunction with low levels of leisure time PA, university employees appear to be prime candidates for workplace interventions to reduce physical inactivity
Management of geomorphosites in high tourist vocation area: an example of Geo-Hiking maps in the Alpe di Fanes (Natural Park of Fanes-Senes-Braies, Italian Dolomites).
Hiking tourism, which combines sport activities and appreciation of Nature, is today one of the main economic activities and among the markets that will experience a great increase in the near future. This paper illustrates a methodology to develop a thematic map, the “geo-hiking map”, which emphasises only the landscape elements that the tourist can recognise and observe, as well as the possible hazards. The geo-hiking map derives from the combination between the geo-tourist map and the geomorphological-hazard map: the first one is a map of geomorphosites enriched with useful indication for tourists (signed paths, refugees, camps etc.); the second one shows hazard levels of different landslide types, snow avalanches and floods. A prototype case study has been chosen within the Natural Park of Fanes-Senes-Braies (Dolomites, Italy). The area has a strong hiking-tourism vocation thanks to its spectacular high-mountain landscape and a dense network of hiking tracks. This innovative study could represent an important instrument for a responsible and safe fruition of high-mountain tourist areas: it combines a cultural dimension of the geomorphological landscape with a conscious respect of its natural behaviour
Detection and characterization of a 500 μm dust emissivity excess in the Galactic plane using Herschel/Hi-GAL observations
Context. Past and recent observations have revealed unexpected variations in the far-infrared – millimeter (FIR-mm) dust emissivity in the interstellar medium. In the Herschel spectral range, those are often referred to as a 500 μm emission excess. Several dust emission models have been developed to interpret astrophysical data in the FIR-mm domain. However, these are commonly unable to fully reconcile theoretical predictions with observations. In contrast, the recently revised two level system (TLS) model, based on the disordered internal structure of amorphous dust grains, seems to provide a promising way of interpreting existing data.
Aims. The newly available Herschel infrared GALactic (Hi-GAL) data, which covers most of the inner Milky Way, offers a unique opportunity to investigate possible variations in the dust emission properties both with wavelength and environment. The goal of our analysis is to constrain the internal structure of the largest dust grains on Galactic scales, in the framework of the TLS model.
Methods. By combining the IRIS (Improved Reprocessing of the IRAS Survey) 100 μm with the Hi-GAL 160, 250, 350, and 500 μm data, we model the dust emission spectra in each pixel of the Hi-GAL maps, using both the TLS model and, for comparison, a single modified black-body fit. The effect of temperature mixing along the line of sight is investigated to test the robustness of our results.
Results. We find a slight decrease in the dust temperature with distance from the Galactic center, confirming previous results. We also report the detection of a significant 500 μm emissivity excess in the peripheral regions of the plane (35° < |l| < 70°) of about 13–15% of the emissivity, which can reach up to 20% in some HII regions. We present the spatial distributions of the best-fit values for the two main parameters of the TLS model, i.e. the charge correlation length, lc, used to characterize the disordered charge distribution (DCD) part of the model, and the amplitude A of the TLS processes with respect to the DCD effect. These distributions illustrate the variations in the dust properties with environment, in particular the plausible existence of an overall gradient with distance to the Galactic center. A comparison with previous findings in the solar neighborhood shows that the local value of the excess is less than expected from the Galactic gradient observed here
Free and protein-conjugated polyamines in mouse epidermal cells. Effect of high calcium and retinoic acid.
We have investigated polyamine metabolism in primary cultures of mouse epidermal cells. These cells, which grow at low Ca2+ levels as a monolayer with characteristics of basal cells, terminally differentiate when the extracellular Ca2+ level is raised above 1 mM. The cellular levels of free polyamines were measured, and, after incubation of cell cultures with [3H]putrescine, the distribution of label in both acid-soluble and acid-insoluble cellular components was examined. Free polyamine levels were reduced in cells induced to differentiate. Treatment with retinoic acid, which prevents differentiation and causes increased proliferation, resulted in an increase in free putrescine. Upon adjustment of the calcium concentration to a level that induces differentiation, the enzyme transglutaminase was activated, and a concomitant increase in the level of both protein-bound mono- and bis-gamma-glutamyl derivatives of putrescine and spermidine was observed. Isolation of a material of apparent molecular weight about 6000 which contains only mono-gamma-glutamylpolyamines and the finding of both mono- and bis-gamma-glutamylpolyamines in the protein fraction containing cornified cell envelopes provided the basis for speculation on polyamines in envelope formation. Our data suggest that polyamines play a role during epidermal cell differentiation through transglutaminase-mediated post-translational modification
Multiplet Structure below Threshold in Appearance-Potential Spectra—Lanthanum N4,5
We present the N4,5 appearance-potential spectrum of La. Structure exists at energies lower than the threshold energy for transitions terminating at the Fermi level. Several similarities between optical absorption spectra and our results are discussed. These results contradict the simple model usually used to interpret appearance-potential spectra and emphasize the need for a new theory
Soft-x-ray appearance potential spectra of La and Ce from 0 to 1400 eV
The soft-x-ray appearance potential spectra were measured for La and Ce in the 0-1400-eV range. The 3d and 4dspectra exhibited prominent structure, which is discussed along with x-ray absorption and emission data. The excited electron and the core hole interact strongly, and there is evidence for additional interaction with the projectile electron. The two-density-of-states model of Wendin seems promising for explaining the spectra, but it must be extended to allow for the interaction of the projectile electron with the excited atom. The effects of oxidation are described
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