Patterns of influenza-like illness and vaccination coverage on Liberty University\u27s campus

Graduate Applie

Co-design and content validity of the movement measurement in the early years (MoveMEY) tool for assessing movement behaviour of pre-school aged children

Abstract Background Movement behaviours (physical activity, sedentary behaviour, and sleep) are important for pre-school children’s health and development. Currently, no tools with appropriate content validity exist that concurrently capture these movement behaviours in young children. The aim of this study was to co-design and assess the content validity of a novel tool to concurrently measure movement behaviours in pre-school aged children (aged 3–4 years). Methods We followed four distinct steps to develop and assess the content validity of Movement Measurement in the Early Years (MoveMEY): (1) We conducted an extensive literature search, to identify pre-existing proxy measurement tools (questionnaires and diaries) to inform the design of a novel tool, which aimed to effectively capture movement behaviour guidelines of pre-school aged children. (2) We facilitated focus group discussions with parents and carers of pre-school aged children (n = 11) and (3) a qualitative survey with free text responses was completed by topic relevant researchers (n = 6), to co-design the measurement tool. (4) We assessed the content validity of the developed tool, MoveMEY, through interviews with parents of pre-school aged children (n = 12) following piloting of the tool. Results We developed an initial version of MoveMEY based on the format of an existing questionnaire and by mapping the content of questions to the guidelines. Co-design of MoveMEY resulted in changes to the format (e.g. short questionnaire to a seven-day diary) and content (e.g. inclusion of ‘general information’ questions on illness, disabilities and sleep disturbances; question on screen time before bed). Content validity assessment demonstrated that the items of MoveMEY were relevant and comprehensive for the assessment of children’s movement behaviours. MoveMEY was felt to be comprehensible, however, parental suggestions were implemented to finalise and improve MoveMEY (e.g. adding examples to questions aiming to detect moderate to vigorous physical activity). Conclusion MoveMEY is the first co-designed measurement tool that has relevance for assessing the movement behaviour guidelines of pre-school aged children. Parent/carer and topic relevant researcher involvement throughout the development process resulted in a seven-day daily reported activity diary that is comprehensive of children’s movement behaviours and comprehensible to parents and carers

Adult Online Hate, Harassment and Abuse: A Rapid Evidence Assessment

The development of email and social media platforms has changed the way in which people interact with each other. The open sharing of personal data in public forums has resulted in online harassment in its many forms becoming increasingly problematic. The number of people having negative online experiences is increasing, with close to half of adult internet users reporting having seen hateful content online in the past year. This report presents findings from a collaborative study undertaken by the University of East London (UEL) and the London School of Economics and Political Science (LSE). It describes the findings from a Rapid Evidence Assessment (REA) of the evidence base in relation to adult online safety undertaken on behalf of the Department for Digital, Culture, Media & Sport (DCMS). The research was undertaken on behalf of the UK Council for Internet Safety Evidence Group. This REA focuses on exploring internet safety issues amongst adults, given the expansion of the remit of the UK Council for Child Internet Safety (UKCCIS) to include adults in the context of the new Internet Safety Strategy (2018) and Online Harms White Paper (2019)

Chilling Aeration to Control Pests and Maintain Grain Quality during In-Bin Storage of Wheat in Kansas

Chilling aeration of stored grain is becoming very popular around the world since it offers many advantages in situations where ambient air conditions are not adequate to cool grain. It allows to cool grain, independent of ambient conditions, to “safe” temperatures where insect, fungi, and spoilage development is reduced to the minimum, and at the same time can potentially reduce chemical control use. The objective of this research was to evaluate the effectiveness of chilling aeration to preserve grain quality and control insect-pests. The research trial was developed from August to November 2015 in Central Kansas in two 1,270 metric tons (MT) steel bins with low-moisture wheat from the 2015 summer harvest. One bin was chilled and the other was used as a control (ambient aeration). Variables evaluated were: moisture content (MC), grain and flour quality, insect-pest development and reproduction rate, insect fragments per kg, and fungi presence. Chilling aeration cooled the grain in 135 hours to an average of 17⁰C, with minimum variation through the four months. Ambient aeration in the control bin cooled the grain to an average of 22⁰C after 308 hours, with variation over 16⁰C through the four months. Lower temperatures significantly diminished insect development and reproduction rate. Flour quality was better preserved in the chilled than in the control bin. There was no significant effect on MC, grain quality or fungi presence. The energy cost of running the grain chiller was 0.22 $/MT more than the cost of ambient aeration in the control bin

Chilled aeration to control pests and maintain grain quality during the summer storage of wheat in north central region of Kansas: Presentation

Chilled aeration allows to cool grain, independent of ambient conditions, to "safe" temperatures where insect, fungi, and spoilage is reduced to the minimum. The objective of this research was to evaluate the advantages of using grain chilling to preserve the quality of grain and reduce post-harvest losses, compared to conventional aeration and storage strategies used during the summer storage of wheat in Central Kansas, U.S.A. The research trials were developed in two 1,350 metric ton (t) steel silos in a Farmer’s Cooperative during the summer and fall of 2015 and 2016. One of the silos was chilled and the other was used as a control managed by the Cooperative. Variables evaluated were: grain temperature, moisture content (MC), grain quality, insect development and reproduction rate. The chilling treatment reduced the grain temperature from 28°C- 39°C to a minimum of 17°C- 17.6°C in less than 250 hours. Grain temperatures below 25°C were not possible during the summer using ambient aeration. Minimum variation of MC was observed in the Chilled silo while ambient aeration reduced the MC by 0.5%. Reproduction rates of RFB and LGB were significantly reduced by chilled temperatures lower than 17°C. Lower temperatures also reduced insects discovered in probe traps and insect damaged kernels (IDK). The energy cost of the grain chiller was between 0.26 US $/t- 0.32 US$/t higher than ambient aeration.Chilled aeration allows to cool grain, independent of ambient conditions, to "safe" temperatures where insect, fungi, and spoilage is reduced to the minimum. The objective of this research was to evaluate the advantages of using grain chilling to preserve the quality of grain and reduce post-harvest losses, compared to conventional aeration and storage strategies used during the summer storage of wheat in Central Kansas, U.S.A. The research trials were developed in two 1,350 metric ton (t) steel silos in a Farmer’s Cooperative during the summer and fall of 2015 and 2016. One of the silos was chilled and the other was used as a control managed by the Cooperative. Variables evaluated were: grain temperature, moisture content (MC), grain quality, insect development and reproduction rate. The chilling treatment reduced the grain temperature from 28°C- 39°C to a minimum of 17°C- 17.6°C in less than 250 hours. Grain temperatures below 25°C were not possible during the summer using ambient aeration. Minimum variation of MC was observed in the Chilled silo while ambient aeration reduced the MC by 0.5%. Reproduction rates of RFB and LGB were significantly reduced by chilled temperatures lower than 17°C. Lower temperatures also reduced insects discovered in probe traps and insect damaged kernels (IDK). The energy cost of the grain chiller was between 0.26 US $/t- 0.32 US$/t higher than ambient aeration

A systematic review of the validity, reliability, and feasibility of measurement tools used to assess the physical activity and sedentary behaviour of pre-school aged children

Physical activity (PA) and sedentary behaviour (SB) of pre-school aged children are associated with important health and developmental outcomes. Accurate measurement of these behaviours in young children is critical for research and practice in this area. The aim of this review was to examine the validity, reliability, and feasibility of measurement tools used to assess PA and SB of pre-school aged children. Searches of electronic databases, and manual searching, were conducted to identify articles that examined the measurement properties (validity, reliability or feasibility) of measurement tools used to examine PA and/or SB of pre-school aged children (3–7 years old). Following screening, data were extracted and risk of bias assessment completed on all included articles. A total of 69 articles, describing 75 individual studies were included. Studies assessed measurement tools for PA (n = 27), SB (n = 5), and both PA and SB (n = 43). Outcome measures of PA and SB differed between studies (e.g. moderate to vigorous activity, step count, posture allocation). Most studies examined the measurement properties of one measurement tool only (n = 65). Measurement tools examined included: calorimetry, direct observation, combined heart rate and accelerometry, heart rate monitors, accelerometers, pedometers, and proxy report (parent, carer or teacher reported) measures (questionnaires or diaries). Studies most frequently assessed the validity (criterion and convergent) (n = 65), face and content validity (n = 2), test-retest reliability (n = 10) and intra-instrument reliability (n = 1) of the measurement tools. Feasibility data was abstracted from 41 studies. Multiple measurement tools used to measure PA and SB in pre-school aged children showed some degree of validity, reliability and feasibility, but often for different purposes. Accelerometers, including the Actigraph (in particular GT3X versions), Actical, ActivPAL and Fitbit (Flex and Zip), and proxy reported measurement tools used in combination may be useful for a range of outcome measures, to measure intensity alongside contextual information

Impact of The Daily Mile on children's physical and mental health, and educational attainment in primary schools: iMprOVE cohort study protocol.

Funder: Cancer Research UKFunder: British Heart FoundationIntroductionSchool-based active mile initiatives such as The Daily Mile (TDM) are widely promoted to address shortfalls in meeting physical activity recommendations. The iMprOVE Study aims to examine the impact of TDM on children's physical and mental health and educational attainment throughout primary school. METHODS AND ANALYSIS: iMprOVE is a longitudinal quasi-experimental cohort study. We will send a survey to all state-funded primary schools in Greater London to identify participation in TDM. The survey responses will be used for non-random allocation to either the intervention group (Daily Mile schools) or to the control group (non-Daily Mile schools). We aim to recruit 3533 year 1 children (aged 5-6 years) from 77 primary schools and follow them up annually until the end of their primary school years. Data collection taking place at baseline (children in school year 1) and each primary school year thereafter includes device-based measures of moderate-to-vigorous physical activity (MVPA) and questionnaires to measure mental health (Strengths and Difficulties Questionnaire) and educational attainment (ratings from 'below expected' to 'above expected levels'). The primary outcome is the mean change in MVPA minutes from baseline to year 6 during the school day among the intervention group compared with controls. We will use multilevel linear regression models adjusting for sociodemographic data and participation in TDM. The study is powered to detect a 10% (5.5 min) difference between the intervention and control group which would be considered clinically significant.Ethics and disseminationEthics has been approved from Imperial College Research Ethics Committee, reference 20IC6127. Key findings will be disseminated to the public through research networks, social, print and media broadcasts, community engagement opportunities and schools. We will work with policy-makers for direct application and impact of our findings

Impact of The Daily Mile on children's physical and mental health, and educational attainment in primary schools: iMprOVE cohort study protocol.

Funder: Cancer Research UKFunder: British Heart FoundationIntroductionSchool-based active mile initiatives such as The Daily Mile (TDM) are widely promoted to address shortfalls in meeting physical activity recommendations. The iMprOVE Study aims to examine the impact of TDM on children's physical and mental health and educational attainment throughout primary school. METHODS AND ANALYSIS: iMprOVE is a longitudinal quasi-experimental cohort study. We will send a survey to all state-funded primary schools in Greater London to identify participation in TDM. The survey responses will be used for non-random allocation to either the intervention group (Daily Mile schools) or to the control group (non-Daily Mile schools). We aim to recruit 3533 year 1 children (aged 5-6 years) from 77 primary schools and follow them up annually until the end of their primary school years. Data collection taking place at baseline (children in school year 1) and each primary school year thereafter includes device-based measures of moderate-to-vigorous physical activity (MVPA) and questionnaires to measure mental health (Strengths and Difficulties Questionnaire) and educational attainment (ratings from 'below expected' to 'above expected levels'). The primary outcome is the mean change in MVPA minutes from baseline to year 6 during the school day among the intervention group compared with controls. We will use multilevel linear regression models adjusting for sociodemographic data and participation in TDM. The study is powered to detect a 10% (5.5 min) difference between the intervention and control group which would be considered clinically significant.Ethics and disseminationEthics has been approved from Imperial College Research Ethics Committee, reference 20IC6127. Key findings will be disseminated to the public through research networks, social, print and media broadcasts, community engagement opportunities and schools. We will work with policy-makers for direct application and impact of our findings

Molecular characterisation of two homoeologous elicitor-responsive lipin genes in cotton

The identification and molecular characterisation of two lipin-like gene copies (GhLIPN) in cotton, Gossypium hirsutum, an allotetraploid derived from two progenitor diploid Gossypium species, is described. Sequence analyses of the GhLIPN copies, designated GhLIPN-1 and -2, revealed that they contain 11 exons, separated by ten introns. They each have a 2,643 bp open reading frame that encodes 880 aa proteins, and share a 97.7 and 95.5 % sequence similarity at the translated nucleotide and amino acid level, respectively. The GhLIPN genes have a distinct domain architecture consisting of an archetypical N-terminal lipin domain, followed by a haloacid dehalogenase (HAD) domain towards the C-terminus. A Southern blot did not distinguish between the two gene copies, which suggests that they may be homoeologs rather than paralogs. GhLIPN-2 is more similar to a homoeologous sequence from G. raimondii, representing the ancestral D-genome, compared to GhLIPN-1 that matches G. herbaceum and that represents the A-genome. Our data indicate that GhLIPN-1 and GhLIPN-2 are homoeologs that derive from the A- and the D-diploid genomes, respectively. The promoter sequences of GhLIPN-1 and -2 differ by 56 %, as a result of multiple indels. In silico analysis of the promoter regions revealed that both genes contain numerous putative defence-related and elicitor-responsive cis-elements that support a role for GhLIPN in defence responses. Relative quantification real-time PCR confirmed the up-regulation in response to a cell-wall-derived V. dahliae elicitor, which supported the association of GhLIPN with defence signalling. The results add a new dimension to the proposed roles of lipins in plants by suggesting that lipins may have a role in defence signalling.The South African National Research Foundation and the University of Johannesburg.http://link.springer.com/journal/438hb2013ab201