Mutual-Excitation of Cryptocurrency Market Returns and Social Media Topics

Cryptocurrencies have recently experienced a new wave of price volatility and interest; activity within social media communities relating to cryptocurrencies has increased significantly. There is currently limited documented knowledge of factors which could indicate future price movements. This paper aims to decipher relationships between cryptocurrency price changes and topic discussion on social media to provide, among other things, an understanding of which topics are indicative of future price movements. To achieve this a well-known dynamic topic modelling approach is applied to social media communication to retrieve information about the temporal occurrence of various topics. A Hawkes model is then applied to find interactions between topics and cryptocurrency prices. The results show particular topics tend to precede certain types of price movements, for example the discussion of 'risk and investment vs trading' being indicative of price falls, the discussion of 'substantial price movements' being indicative of volatility, and the discussion of 'fundamental cryptocurrency value' by technical communities being indicative of price rises. The knowledge of topic relationships gained here could be built into a real-time system, providing trading or alerting signals.Comment: 3rd International Conference on Knowledge Engineering and Applications (ICKEA 2018) - Moscow, Russia (June 25-27 2018

The developing concept of “computational thinking”.

A table referencing work related to the developing concept of “computational thinking”

Ratio-based estimators for a change point in persistence

Published version © 2012 Elsevier B.V. All rights reserved. Open Access funded by Economic and Social Research Council under a Creative Commons licenseWe study estimation of the date of change in persistence, from I(0) to I(1) or vice versa. Contrary to statements in the original papers, our analytical results establish that the ratio-based break point estimators of Kim [Kim, J.Y., 2000. Detection of change in persistence of a linear time series. Journal of Econometrics 95, 97–116], Kim et al. [Kim, J.Y., Belaire-Franch, J., Badillo Amador, R., 2002. Corringendum to ‘‘Detection of change in persistence of a linear time series’’. Journal of Econometrics 109, 389–392] and Busetti and Taylor [Busetti, F., Taylor, A.M.R., 2004. Tests of stationarity against a change in persistence. Journal of Econometrics 123, 33–66] are inconsistent when a mean (or other deterministic component) is estimated for the process. In such cases, the estimators converge to random variables with upper bound given by the true break date when persistence changes from I(0) to I(1). A Monte Carlo study confirms the large sample downward bias and also finds substantial biases in moderate sized samples, partly due to properties at the end points of the search interval.Economic and Social Research Counci

Shelley Phillips and Denise Masters in a Junior Recital

This is the program for the junior recital of mezzo-soprano, Shelley Phillips, accompanied by pianist, Chris Norris, and soprano, Denise Masters, accompanied by pianist, John Turner. The recital was held on March 9, 1990, in the Mabee Fine Arts Center Recital Hall

Le consentement à la recherche en pharmacogénomique

[À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu]Cet article analyse les pratiques éthiques et légales en matière de consentement éclairé dans le domaine de la recherche en pharmacogénomique. Les auteurs y examinent la manière dont les politiques internationales, régionales et nationales répondent aux nouveaux enjeux éthiques suscités par la pharmacogénomique. Ils concluent que le cadre éthique servant à guider les chercheurs dans ce domaine est encore en développement et nécessite un approfondissement pour répondre aux enjeux soulevés par cette importante discipli

Lived Experiences of Women Over 50 Who Have Experienced Involuntary Job Loss

Both the short-term and long-term unemployment rates for older workers in the United States have increased significantly since the 2007 recession. Researchers who examine the impact of involuntary job loss have predominantly focused on the experiences of men. Limited prior research exists on the job loss experiences of women over 50 years of age compared to men. The goal of this study was to address this gap in knowledge by examining the lived experiences of women over 50 who had experienced involuntary job loss, the barriers faced to reemployment, and the ways women overcame the barriers to reemployment. A phenomenological design was employed to gather data from a convenience sample of 10 women in a northeastern metropolitan city. Guided by the frameworks of Bandura and Leana and Feldman, this transcendental approach aimed to capture the lived experiences of the women who incurred involuntary job loss. Data transcribed from audio-taped interviews were manually coded and aligned with the appropriate research question. The findings highlighted the emotions, finances, family and social life of women following job loss. The findings suggest women faced age discrimination, organizational practices, technological challenges, and stereotypical beliefs in their attempts toward reemployment. The results of the study can be used to inform organizational leaders of the need for greater emphasis on programs offering solutions to older female workers seeking reemployment. The study promotes potential positive social change by informing organizational leaders of the experiences of women over 50 who had experienced involuntary job loss

Consent in Pharmacogenomic research

[À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu]This article analyzes the emerging ethical and legal requirements for informed consent in pharmacogenomic research. It reviews how policies at the international, regional and national levels have responded to the ethical challenges raised by this new research area. It concludes that the pharmacogenomic policy framework is still in its infancy and needs to be further developed to answer the challenges raised by this important discipline

Genotoxicity of complex chemical mixtures

Complex chemical mixtures are ubiquitous in the environment. Humans are frequently exposed to these mixtures; therefore, it is important to understand potential interactions of chemical mixtures. Mixture interactions may influence the absorption, distribution, metabolism or excretion of the components of a complex mixture. The research conducted for this dissertation has coupled chemical fractionation with in vitro and in vivo bioassays to assess the potential carcinogenic risk of complex mixtures. A non-aqueous phase liquid from a wood treatment plant was separated into acid (AF), base (BF) and neutral fractions (NF). The NF was further enriched using column chromatography to produce a polychlorinated dinbenzo-p-dioxin (PCDD) and a polycyclic aromatic hydrocarbon (PAH) fraction. The genotoxicity of these mixtures were assessed via analytical quantification, in vitro (Salmonella microsome and E. coli prophage induction) and in vivo (32P-postlabeling) bioassays. The NF was further tested to measure bulky DNA adducts and induction of tumor formation. The AF contained the highest level of pentachlorophenol and the highest concentration of total PAHs. Although the carcinogenic PAHs were highest in the PCDD fraction, the highest concentrations of benzo(a)pyrene (BAP), indeno(1,2,3-cd)pyrene and dibenz(a,h)anthracene were detected in the PAH fraction. A positive genotoxic response in Salmonella was induced by the crude extract, the PAH and BF, whereas the AF and BF induced a positive response in the E. coli assay. In vivo, the PAH fraction induced the highest DNA adduct frequencies in the lung. The NF, reconstituted mixture (RM) (which includes equivalent concentrations of seven carcinogenic PAHs in the NF), BAP and the NF amended with BAP (NF+BAP) were all tested in an infant mouse model. At the highest dose, after a 24 hr exposure, NF+BAP had the highest total DNA adducts measured in liver which was three to seven times higher than with other treatments. Adduct levels were comparable to the control after 280 days. The highest incidence of tumors was observed in the liver. At the high dose, NF+BAP elicited the highest incidence of tumors. The results of this research confirm previous studies and indicate that the carcinogenic potential of PAH mixtures may be greater than predicted by chemical analysis