572 research outputs found
Photoionization and dynamic solvation of the excited states of 7-azaindole
The excited-state photophysics of the biological probe, 7-azaindole, are examined in water and methanol. Electrons in a presolvated state absorbing in the infrared appear within the excitation pulse width of 130 fs. 330 i 100 fs is required for the presolvated electron to achieve the spectrum characteristic of the completely solvated electron. An excited-state transient absorbance decays in -350 fs for 7-azaindole and its methylated analog, N1-methyl-7-azaindole (1M7AI), in the region 400-450 nm in water and methanol. The instantaneous appearance of the electron in the infrared is attributed to the decay of the lLb excited-state that overlaps the \u27La excited state of 7-azaindole. The rapid decay of the excited-state transient absorbance is attributed to preferential, dynamic solvation of the \u27La state. 7-Azaindole thus provides an interesting example of a molecule whose excited state is continuously and dynamically solvated but which also produces a species, e,,-, whose solvation appears to occur in a stepwise process
Domain Structure of the Staphylococcus aureus Collagen Adhesin
Sequence analysis of surface proteins from Gram-positive bacteria indicates a composite organization consisting of unique and repeated segments. Thus, these proteins may contain discrete domains that could fold independently. In this paper, we have used a panel of biophysical methods, including gel permeation chromatography, analytical ultracentrifugation, circular dichroism, and fluorescence spectroscopy, to analyze the structural organization of the Staphylococcus aureus collagen adhesin, CNA. Our results indicate that the structure, function, and folding of the ligand-binding domain (A) are not affected by the presence or absence of the other major domain (B). In addition, little or no interaction is observed between the nearly identical repeat units within the B domain. We propose that CNA is indeed a mosaic protein in which the different domains previously indicated by sequence analysis operate independently
Examination of Sea Ice Cover in Norwegian Fjords
Presented are two steps being taken to examine sea ice coverage in Norwegian fjords as part of a larger study to improve our understanding of ice formation and breakup processes in these regions and implications for oil spill response. First, working with Google Earth Engine, MODIS images will be analyzed to determine where and when seasonal ice formation occurred along the Norwegian coastline since 2000. Here we summarize a simple method developed to quantify ice area in these regions to examine trends through the ice season and between years. While the larger study will cover a number of fjords, as an example focus is placed on Efjord, located in Nordland county, which has experienced large variations in ice coverage between years. We discuss the use of other datasets to determine the causes of such fluctuations focusing on the close relationship between run-off and ice cover in Efjord. Second, measurements of water temperature and salinity and ice thickness, stratigraphy, and salinity will be gathered over a three year period to better understand the ice observed in the MODIS images. The first set of measurements collected in November 2017 before freeze up are discussed below. In addition, initial images collected from time lapse cameras positioned to observe general weather and ocean conditions and the initial freeze up of ice are presented.submittedVersio
Local Spin-Gauge Symmetry of the Bose-Einstein Condensates in Atomic Gases
The Bose-Einstein condensates of alkali atomic gases are spinor fields with
local ``spin-gauge" symmetry. This symmetry is manifested by a superfluid
velocity (or gauge field) generated by the Berry phase of the
spin field. In ``static" traps, splits the degeneracy of the
harmonic energy levels, breaks the inversion symmetry of the vortex nucleation
frequency , and can lead to {\em vortex ground states}. The
inversion symmetry of , however, is not broken in ``dynamic"
traps. Rotations of the atom cloud can be generated by adiabatic effects
without physically rotating the entire trap.Comment: Typos in the previous version corrected, thanks to the careful
reading of Daniel L. Cox. 13 pages + 2 Figures in uuencode + gzip for
Evaluation of a Technology-Based Survivor Care Plan for Breast Cancer Survivors: Pre-Post Pilot Study.
BACKGROUND: As of 2016, almost 16 million individuals were cancer survivors, including over 3.5 million survivors of breast cancer. Because cancer survivors are living longer and have unique health care needs, the Institute of Medicine proposed a survivor care plan as a way to alleviate the many medical, emotional, and care coordination problems of survivors.
OBJECTIVE: This pilot study for breast cancer survivors was undertaken to: (1) examine self-reported changes in knowledge, confidence, and activation from before receipt to after receipt of a survivor care plan; and (2) describe survivor preferences for, and satisfaction with, a technology-based survivor care plan.
METHODS: A single group pretest-posttest design was used to study breast cancer survivors in an academic cancer center and a community cancer center during their medical visit after they completed chemotherapy. The intervention was a technology-based survivor care plan. Measures were taken before, immediately after, and 1 month after receipt of the survivor care plan.
RESULTS: A total of 38 breast cancer survivors agreed to participate in the study. Compared to baseline levels before receipt of the survivor care plan, participants reported increased knowledge both immediately after its receipt at the academic center (P\u3c.001) and the community center (P\u3c.001) as well as one month later at the academic center (P=.002) and the community center (P\u3c.001). Participants also reported increased confidence immediately following receipt of the survivor care plan at the academic center (P=.63) and the community center (P=.003) and one month later at both the academic center (P=.63) and the community center (P\u3c.001). Activation was increased from baseline to post-survivor care plan at both the academic center (P=.05) and community center (P\u3c.001) as well as from baseline to 1-month follow-up at the academic center (P=.56) and the community center (P\u3c.001). Overall, community center participants had lower knowledge, confidence, and activation at baseline compared with academic center participants. Overall, 22/38 (58%) participants chose the fully functional electronic survivor care plan. However, 12/23 (52%) in the community center group chose the paper version compared to 4/15 (27%) in the academic center group. Satisfaction with the format (38/38 participants) and the content (37/38 participants) of the survivor care plan was high for both groups.
CONCLUSIONS: This study provides evidence that knowledge, confidence, and activation of survivors were associated with implementation of the survivor care plan. This research agrees with previous research showing that cancer survivors found the technology-based survivor care plan to be acceptable. More research is needed to determine the optimal approach to survivor care planning to ensure that all cancer survivors can benefit from it
Critical collapse of collisionless matter - a numerical investigation
In recent years the threshold of black hole formation in spherically
symmetric gravitational collapse has been studied for a variety of matter
models. In this paper the corresponding issue is investigated for a matter
model significantly different from those considered so far in this context. We
study the transition from dispersion to black hole formation in the collapse of
collisionless matter when the initial data is scaled. This is done by means of
a numerical code similar to those commonly used in plasma physics. The result
is that for the initial data for which the solutions were computed, most of the
matter falls into the black hole whenever a black hole is formed. This results
in a discontinuity in the mass of the black hole at the onset of black hole
formation.Comment: 22 pages, LaTeX, 7 figures (ps-files, automatically included using
psfig
Observation of critical phenomena and self-similarity in the gravitational collapse of radiation fluid
We observe critical phenomena in spherical collapse of radiation fluid. A
sequence of spacetimes is numerically computed, containing
models () that adiabatically disperse and models () that
form a black hole. Near the critical point (), evolutions develop a
self-similar region within which collapse is balanced by a strong,
inward-moving rarefaction wave that holds constant as a function of a
self-similar coordinate . The self-similar solution is known and we show
near-critical evolutions asymptotically approaching it. A critical exponent
is found for supercritical () models.Comment: 10 pages (LaTeX) (to appear in Phys. Rev. Lett.), TAR-039-UN
Dynamics of rotating Bose-Einstein condensates probed by Bragg scattering
Gaseous Bose-Einstein condensates (BECs) have become an important test bed
for studying the dynamics of quantized vortices. In this work we use two-photon
Doppler sensitive Bragg scattering to study the rotation of sodium BECs. We
analyze the microscopic flow field and present laboratory measurements of the
coarse-grained velocity profile. Unlike time-of-flight imaging, Bragg
scattering is sensitive to the direction of rotation and therefore to the phase
of the condensate. In addition, we have non-destructively probed the vortex
flow field using a sequence of two Bragg pulses.Comment: 13 pages, 5 figures. Invited paper submitted to a special issue on
"Nonlinear Waves" of the (Elsevier) journal 'Math. Comput. Simul.', for
participants in the 4th IMACS International Conference on Nonlinear Evolution
Equations and Wave Phenomena (2005). Visit our website at
http://www.physics.gatech.edu/chandra for additional informatio
- …