438 research outputs found

    Co-producing neighbourhood resilience

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    Some aspects of the human body's hydraulics

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    This paper presents some aspects related to the human body's hydraulics in the desire to make readers aware of how to maintain all the blood vessels of the human body in order to maintain the entire healthy, functional, young, vigorous circulatory system for a while the longest possible. The problem is complex because it has to be viewed from all points of view and not only as an isolated system in the body, having aspects of feedback on the whole physiopathology belonging to the human body. The highly circulating system needs permanent maintenance. Self-maintenance is done through various physiological mechanisms tightly linked to each other, including the lymphatic, digestive, renal, lung, nervous, glandular system… It is not possible to completely separate the physiology of a system from the other adjacent systems because they all work synergistically, being permanently controlled by the central and peripheral nervous system

    Biomechanically tunable nano-silica/p-hema structural hydrogels for bone scaffolding

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    Innovative tissue engineering biomimetic hydrogels based on hydrophilic polymers have been investigated for their physical and mechanical properties. 5% to 25% by volume loading PHEMA-nanosilica glassy hybrid samples were equilibrated at 37◦C in aqueous physiological isotonic and hypotonic saline solutions (0.15 and 0.05 M NaCl) simulating two limiting possible compositions of physiological extracellular fluids. The glassy and hydrated hybrid materials were characterized by both dynamo-mechanical properties and equilibrium absorptions in the two physiological-like aqueous solutions. The mechanical and morphological modifications occurring in the samples have been described. The 5% volume nanosilica loading hybrid nanocomposite composition showed mechanical characteristics in the dry and hydrated states that were comparable to those of cortical bone and articular cartilage, respectively, and then chosen for further sorption kinetics characterization. Sorption and swelling kinetics were monitored up to equilibrium. Changes in water activities and osmotic pressures in the water-hybrid systems equilibrated at the two limiting solute molarities of the physiological solutions have been related to the observed anomalous sorption modes using the Flory-Huggins interaction parameter approach. The bulk modulus of the dry and glassy PHEMA-5% nanosilica hybrid at 37◦C has been observed to be comparable with the values of the osmotic pressures generated from the sorption of isotonic and hypotonic solutions. The anomalous sorption modes and swelling rates are coherent with the difference between osmotic swelling pressures and hybrid glassy nano-composite bulk modulus: the lower the differences the higher the swelling rate and equilibrium solution uptakes. Bone tissue engineering benefits of the use of tuneable biomimetic scaffold biomaterials that can be “designed” to act as biocompatible and biomechanically active hybrid interfaces are discussed

    Soft skills and psychological well-being: A study on Italian urban and rural NEETs

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    Soft skills retain a certain importance in fully understanding the NEET phenomenon: however, only few researchers have focused on them specifically. The aim of this work is two-fold: a) to detect the differences in terms of soft skills and psychological well-being between urban and rural NEETs; and b) to evaluate which of the soft skills analysed may be predictors of psychological well-being. A sample of young 6998 18−34 years old representative of the Italian population was used. Although gender and educational attainment play a key role in determining NEET status, the degree of urbanisation must be considered because it appears to influence the well-being and perceived soft skills of a group of NEETs. The present study shows that females with low educational attainment residing in rural areas have lower levels of well-being than females with low educational attainment residing in urban areas. A similar influence exists in relation to one particular soft skill: positive vision. Furthermore, soft skills predict psychological well-being wherein degree of urbanisation and gender seems to play a determining role. Policies should, therefore, consider these issues in their design and implementation phases.info:eu-repo/semantics/publishedVersio
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