The importance of target audiences in the design of training actions

This paper describes the process of definition, conceptualization and implementation of a business course addressed for logistic and industrial managers. This course was designed using a blended methodology, with training in classroom, visits to enterprises and self- study, supported by an eLearning platform. The aim of this work is to create an opportunity to reflect about the decisions and strategies implemented and point future developments

Avaliação da cultura organizacional: Adaptação e validação da versão portuguesa do Denison Organizational Culture Survey

This study presents the results of the adaptation and validation of Denison Organizational Culture Survey (2001) in a sample of 905 employees of 102 Portuguese companies. In the study we confirmed the four-dimensional structure and twelve of the questionnaire indicators. Both correlations between different indicators and dimensions as well their internal consistency, showed similar results to those obtained in the original version that justify the adaptation and validation of this instrument for the context of Portuguese companies in the study.Este estudo apresenta os resultados da adaptação e validação do questionário de Cultura Organizacional (Denison Organizational Culture Survey, 2001). O estudo incidiu sobre uma amostra de 905 colaboradores de 102 empresas Portuguesas. No estudo confirmámos a estrutura de quatro dimensões e de doze indicadores do referido questionário. Tanto as correlações entre os diferentes indicadores e dimensões, como a consistência interna das mesmas, apresentaram resultados semelhantes aos obtidos na versão original que justificam a adaptação e validação deste instrumento para o contexto de empresas portuguesas em estudo

Concepção de roteiros de formação para a oferta formativa do Programa Aveiro Norte

Este artigo tem por objectivo a apresentação de um roteiro de formação baseado no contexto de estudo acompanhado que recorre à conceptualização de um roteiro de formação/roteiro de aula que identifica os vários módulos formativos ou disciplinas de ensino, organizados através de marcos de aprendizagem indexados aos conteúdos de formação e ensino propostos com o intuito de que estes sejam aprendidos com maior sucesso

Efeito de diferentes ordenhadores sobre o comportamento de ordenha de vacas Jersey no estado do Rio Grande do Sul.

ZOOTEC 2011

Sentinel lymph node mapping and intraoperative assessment in a prospective, international, multicentre, observational trial of patients with cervical cancer: The SENTIX trial

Background: SENTIX (ENGOT-CX2/CEEGOG-CX1) is an international, multi centre, prospective observational trial evaluating sentinel lymph node (SLN) biopsy without pelvic lymph node dissection in patients with early-stage cervical cancer. We report the final preplanned analysis of the secondary end-points: SLN mapping and outcomes of intraoperative SLN pathology. Methods: Forty-seven sites (18 countries) with experience of SLN biopsy participated in SENTIX. We preregistered patients with stage IA1/lymphovascular space invasion-positive to IB2 (4 cm or smaller or 2 cm or smaller for fertility-sparing treatment) cervical cancer without suspicious lymph nodes on imaging before surgery. SLN frozen section assessment and pathological ultrastaging were mandatory. Patients were registered postoperatively if SLN were bilaterally detected in the pelvis, and frozen sections were negative. Trial registration: ClinicalTrials.gov (NCT02494063). Results: We analysed data for 395 preregistered patients. Bilateral detection was achieved in 91% (355/395), and it was unaffected by tumour size, tumour stage or body mass index, but it was lower in older patients, in patients who underwent open surgery, and in sites with fewer cases. No SLN were found outside the seven anatomical pelvic regions. Most SLN and positive SLN were localised below the common iliac artery bifurcation. Single positive SLN above the iliac bifurcation were found in 2% of cases. Frozen sections failed to detect 54% of positive lymph nodes (pN1), including 28% of cases with macrometastases and 90% with micrometastases. Interpretation: SLN biopsy can achieve high bilateral SLN detection in patients with tumours of 4 cm or smaller. At experienced centres, all SLN were found in the pelvis, and most were located below the iliac vessel bifurcation. SLN frozen section assessment is an unreliable tool for intraoperative triage because it only detects about half of N1 cases. (C) 2020 The Author(s). Published by Elsevier Ltd

The influence of technology, organizational size and age on Innovation

The purpose of this work is to assess the influence of organizational variables (technology, organization size and age) on organizational innovation. A total of 102 top-level managers of Portuguese organizations, from different sectors, sizes, and ages answered a questionnaire concerning innovation activity in their organization. The results of this exploratory study highlighted positive as well as negative significant relationships of these organizational variables in different dimensions of the innovation process. This can be useful to better understand how innovation occurs within and between different industries or companies. This study includes objective measures that can capture the innovative efforts in an organization more directly and identify some organizational characteristics that may affect innovation activity.info:eu-repo/semantics/publishedVersio

Wertheim-Meigs operation for cervical cancer and complementary therapy: critical analysis of 5 years

OBJECTIVES: Review and critical analysis of the Wertheim-Meigs Operations performed at our institution in the context of cervical cancer and to assess the proportion who underwent treatment with adjuvant radiotherapy (with or without chemotherapy) and the main indications. MATERIAL AND METHODS: Retrospective review of Wertheim-Meigs operations, conducted in the context of carcinoma of the cervix, between 01.01.2005 and 31.12.2010, through consultation with clinical processes. It was later performed a descriptive statistical analysis of the cases. RESULTS: During this period 119 Wertheim-Meigs Operations were performed. Four were excluded: two, for primary indication for adjuvant therapy due to histological subtype; two for the inability to exclude invasive disease preoperatively and the invasion was not confirmed after surgery. A total of 115 cases were reviewed and analyzed, and of these 50 (43.5%) underwent complementary therapy, the main indication being the presence of lymphovascular invasion in 21 cases (42% of cases submitted to complementary therapy ). CONCLUSIONS: The mean age of patients undergoing radical surgery is 49 years, with stage IB1 most often determining its performance. Complementary therapy was performed in 43.5% of cases, the main indication being lymphovascular invasion (42%) followed by lymph node invasion (16%). Internal audit to the Service is satisfactory, with 16.5% surgical complication rate and high technical performance

Clinical benefit of hormonal therapy in advanced ovarian cancer

Objectives: To evaluate the benefit of hormonal therapy in advanced ovarian carcinoma. Materials and Methods: The present authors reviewed the data of advanced epithelial ovarian cancer patients who underwent hormonal therapy between 2009 and 2016. Primary endpoint was clinical benefit. Secondary endpoints were overall response rate, CA 125 response, overall survival, progression-free survival, and toxicity. Results: The authors identified 47 patients. Median age was 61 years. Serous carcinoma was the main histologic subtype (70%). Hormone receptor expression was positive in 23% of patients. Previous to hormonal therapy, 60% of patients were treated with two or more chemotherapy regimens (range 2-8). Hormonal therapy was initiated in 34% of patients due to disease progression and the remaining as maintenance therapy. No relevant toxicity was reported. Progression-free survival was six months (CI 95% 2.1-9.9) and overall survival was 22 months (CI 95% 13.0-31.0). Based on imaging response criteria, one patient had complete response, 70% had stable disease, and 19% progressed on the first evaluation. Overall clinical benefit was 72%. Discussion: Clinical benefit was superior to the reported in the literature, probably related to its maintenance use between chemotherapy treatments. More prospective studies are needed to determine the real advantage of hormonal therapy in advanced ovarian cancer vs. clinical surveillance, mainly in the maintenance setting, as well as its correlation with hormone receptor expression