An order fitting rule for optimal subspace averaging

The problem of estimating a low-dimensional subspace from a collection of experimentally measured subspaces arises in many applications of statistical signal processing. In this paper we address this problem, and give a solution for the average subspace that minimizes an extrinsic mean-squared error, defined by the squared Frobenius norm between projection matrices. The solution automatically returns the dimension of the optimal average subspace, which is the novel result of the paper. The proposed order fitting rule is based on thresholding the eigenvalues of the average projection matrix, and thus it is free of penalty terms or other tuning parameters commonly used by other rank estimation techniques. Several numerical examples demonstrate the usefulness and applicability of the proposed criterion, showing how the dimension of the average subspace captures the variability of the measured subspaces.The work of I. Santamaría was supported by the Spanish Government through grants PRX14/0028 (Estancias de Movilidad de Profesores, Ministerio de Educación) and by project RACHEL (TEC2013-47141-C4-3-R) funded by the Ministerio de Economía y Competitividad (MINECO). The work of L. L. Scharf was supported by the National Science Foundation (NSF) under grant CCF-1018472

The Status of Spacecraft Bus and Platform Technology Development Under the NASA ISPT Program

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance 2) NASAs Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System, and ultra-lightweight propellant tank technologies. Future direction for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV) 2) multi-mission technologies for Earth Entry Vehicles (MMEEV) and 3) electric propulsion. These technologies are more vehicle and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis

Multiwavelength Monitoring of the Dwarf Seyfert 1 Galaxy NGC 4395. I. A Reverberation-Based Measurement of the Black Hole Mass

A reverberation-mapping program on NGC 4395, the least-luminous known Seyfert 1 galaxy, undertaken with the Space Telescope Imaging Spectrograph on the Hubble Space Telescope, yields a measurement of the mass of the central black hole of 360,000 solar masses. The observations consist of two visits of 5 orbits each, in 2004 April and July. During each of these visits, the UV continuum varied by at least 10% (rms) and only C IV 1549 showed corresponding variations large enough to reliably determine the emission-line lag, which was measured to be of order one hour for both visits. The size of the C IV-emitting region is about a factor of three smaller than expected if the slope of the broad-line region radius-luminosity relationship is identical to that for the H-beta emission line. NGC 4395 is underluminous even for its small black hole mass; the Eddington ratio of 0.0012 is lower than that of any other active galactic nucleus for which a black hole mass measurement has been made by emission-line reverberation.Comment: This replacement is an erratum to be published in The Astrophysical Journal. 3 pages, with one replacement figure and one replacement tabl

Dynamic Failure Properties of the Porcine Medial Collateral Ligament-Bone Complex for Predicting Injury in Automotive Collisions

The goal of this study was to model the dynamic failure properties of ligaments and their attachment sites to facilitate the development of more realistic dynamic finite element models of the human lower extremities for use in automotive collision simulations. Porcine medial collateral ligaments were chosen as a test model due to their similarities in size and geometry with human ligaments. Each porcine medial collateral ligament-bone complex (n = 12) was held in a custom test fixture placed in a drop tower to apply an axial impulsive impact load, applying strain rates ranging from 0.005 s-1 to 145 s-1. The data from the impact tests were analyzed using nonlinear regression to construct model equations for predicting the failure load of ligament-bone complexes subjected to specific strain rates as calculated from finite element knee, thigh, and hip impact simulations. The majority of the ligaments tested failed by tibial avulsion (75%) while the remaining ligaments failed via mid-substance tearing. The failure load ranged from 384 N to 1184 N and was found to increase with the applied strain rate and the product of ligament length and cross-sectional area. The findings of this study indicate the force required to rupture the porcine MCL increases with the applied bone-to-bone strain rate in the range expected from high speed frontal automotive collisions

The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation

Peer reviewedPublisher PD

Detection of the spotted wing drosophila, Drosophila suzukii, in continental sub-Saharan Africa

The spotted wing drosophila, Drosophila suzukii Matsumura, is an insect pest of soft-skinned fruit, native to Eastern Asia. Since 2008, a world-wide dispersal of D. suzukii is seen, characterized by the establishment of the pest in many Asian, American and European countries. While the potential for invasion of continental Africa by D. suzukii has been predicted, its presence has only been shown for Morocco in Northern Africa. Knowledge about a possible establishment in other parts of the continent is needed as a basis for pest management. In 2019, we carried out a first survey in three counties in Kenya to monitor for the presence of D. suzukii using traps baited with a blend of apple cider vinegar and red wine. A total of 389 D. suzukii flies were captured in a fruit farm at Nakuru county, with more female flies being trapped than males. We confirmed the morphological identification of D. suzukii using DNA barcoding. In 2020, we performed a follow-up survey at 14 locations in six counties to delimit the distribution of D. suzukii in the main berry growing zones in Kenya. The survey indicated that so far D. suzukii is restricted to Nakuru county where it was initially detected. This is the first study to provide empirical evidence of D. suzukii in continental sub-Saharan Africa, confirming that the pest is expanding its geographic range intercontinentally. Given the high dispersal potential of D. suzukii, a concerted effort to develop management strategies is a necessity for containment of the pest

Multiwavelength Monitoring of the Dwarf Seyfert 1 Galaxy NGC 4395. II. X-ray and Ultraviolet Continuum Variability

We report on two Chandra observations, and a simultaneous Hubble Space Telescope ultraviolet observation, of the dwarf Seyfert 1 galaxy NGC 4395. Each Chandra observation had a duration of ~30 ks, with a separation of ~50 ks. The spectrum was observed to harden between these observations via a scaling down of the soft-band flux. The inter-observation variability is in a different sense to the observed variability within each observation and is most likely the result of increased absorption. Spectral variations were seen during the first observation suggesting that the X-ray emission is produced in more than one disconnected region. We have also re-analyzed a ~17 ks Chandra observation conducted in 2000. During the three Chandra observations the 2-10 keV flux is about a factor of 2 lower than seen during an XMM-Newton observation conducted in 2003. Moreover, the fractional variability amplitude exhibited during the XMM-Newton observation is significantly softer than seen during the Chandra observations. A power-spectral analysis of the first of the two new Chandra observations revealed a peak at 341s with a formal detection significance of 99%. A similar peak was seen previously in the 2000 Chandra data. However, the detection of this feature is tentative given that it was found in neither the second of our two new Chandra observations nor the XMM-Newton data, and it is much narrower than expected. The Hubble Space Telescope observation was conducted during part of the second Chandra visit. A zero-lag correlation between the ultraviolet and X-ray fluxes was detected with a significance of about 99.5%, consistent with the predictions of the two-phase model for the X-ray emission from active galactic nuclei.Comment: 31 pages, 10 figures, accepted for publication in Ap

Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation.

Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. Although the basic structure of the cilium and the cadre of genes that contribute to ciliary formation and function (the ciliome) are believed to be evolutionarily conserved, the presentation of ciliopathies with narrow, tissue-specific phenotypes and distinct molecular readouts suggests that an unappreciated heterogeneity exists within this organelle. Here, we provide a searchable transcriptomic resource for a curated primary ciliome, detailing various subgroups of differentially expressed genes within the ciliome that display tissue and temporal specificity. Genes within the differentially expressed ciliome exhibited a lower level of functional constraint across species, suggesting organism and cell-specific function adaptation. The biological relevance of ciliary heterogeneity was functionally validated by using Cas9 gene-editing to disrupt ciliary genes that displayed dynamic gene expression profiles during osteogenic differentiation of multipotent neural crest cells. Collectively, this novel primary cilia-focused resource will allow researchers to explore longstanding questions related to how tissue and cell-type specific functions and ciliary heterogeneity may contribute to the range of phenotypes associated with ciliopathies

AN ADVISORY COMMITTEE PROCESS TO PLAN MOOSE MANAGEMENT IN MINNESOTA

Concern over the decline of moose in Minnesota led to a Legislative Session Law mandating that the Department of Natural Resources (DNR) develop a Moose Management and Research Plan (MMP).  Prior to developing the MMP, the DNR was required to form a Moose Advisory Committee (MAC).  The MAC met 8 times in August 2008-July 2009 and  provided management and research recommendations to the DNR in a 45-page report available on the internet.  This paper details the MAC process and serves as a reference for agencies that find themselves in a similar management circumstance.  Procedural decisions, planning needs, and development of the final report are discussed herein