Geostatistical analysis of an experimental stratigraphy

[1] A high-resolution stratigraphic image of a flume-generated deposit was scaled up to sedimentary basin dimensions where a natural log hydraulic conductivity (ln( K)) was assigned to each pixel on the basis of gray scale and conductivity end-members. The synthetic ln( K) map has mean, variance, and frequency distributions that are comparable to a natural alluvial fan deposit. A geostatistical analysis was conducted on selected regions of this map containing fluvial, fluvial/ floodplain, shoreline, turbidite, and deepwater sedimentary facies. Experimental ln(K) variograms were computed along the major and minor statistical axes and horizontal and vertical coordinate axes. Exponential and power law variogram models were fit to obtain an integral scale and Hausdorff measure, respectively. We conclude that the shape of the experimental variogram depends on the problem size in relation to the size of the local-scale heterogeneity. At a given problem scale, multilevel correlation structure is a result of constructing variogram with data pairs of mixed facies types. In multiscale sedimentary systems, stationary correlation structure may occur at separate scales, each corresponding to a particular hierarchy; the integral scale fitted thus becomes dependent on the problem size. The Hausdorff measure obtained has a range comparable to natural geological deposits. It increases from nonstratified to stratified deposits with an approximate cutoff of 0.15. It also increases as the number of facies incorporated in a problem increases. This implies that fractal characteristic of sedimentary rocks is both depositional process - dependent and problem-scale-dependent

Effects of butyltin exposures on MAP kinase-dependent transcription regulators in human natural killer cells

Natural killer (NK) cells are a major immune defense mechanism against cancer development and viral infection. The butyltins (BTs), tributyltin (TBT) and dibutyltin (DBT), have been widely used in industrial and other applications and significantly contaminate the environment. Both TBT and DBT have been detected in human blood. These compounds inhibit the lytic and binding function of human NK cells and thus could increase the incidence of cancer and viral infections. Butyltin (BT)-induced loss of NK function is accompanied by activation of mitogen activated protein kinases (MAPKs) and decreases in expression of cell-surface and cytolytic proteins. MAPKs activate components of the transcription regulator AP-1 and activate the transcription regulator Elk-1. Based on the fact that BTs activate MAPKs and alter protein expression, the current study examined the effect of BT exposures on the levels and phosphorylation states of the components of AP-1 and the phosphorylation state of Elk-1. Exposure to 300 nM TBT for 10 min increased the phosphorylation of c-Jun in NK cells. One hour exposures to 300 nM and 200 nM TBT increased the phosphorylation and overall level of c-Jun. During a 300 nM treatment with TBT for 1 h the binding activity of AP-1 was significantly decreased. There were no significant alterations of AP-1 components or of Elk-1 with DBT exposures. Thus, it appears that TBT-induced alterations on phosphorylation, total levels, and binding activity of c-Jun might contribute to, but are not fully responsible for, TBT-induced alterations of NK protein expression

Sistema de prevenção e combate a incêndios florestais no município de Campinas-SP.

A atividade agropecuária foi a grande responsável pela erradicação da cobertura florestal do Estado de São Paulo. Atualmente, uma das maiores ameaças aos remanescentes florestais é o risco de incêndios. Em Campinas-SP, a evolução do uso das terras acompanhou esta dinâmica. Hoje, esses remanescentes recobrem 2233 ha do Município, representando 2,8% da sua área total, distribuídos em 114 florestas que variam de 1 a 230 ha. Nos últimos 20 anos, a cobertura florestal se manteve estabilizada. São raríssimos os casos atuais de desmatamento, devido ao interesse dos proprietários em preservar essas áreas. Todavia, essas manchas isoladas de matas mesófilas não estão isentas à ocorrência de incêndios. eles destroem a vegetação, determinam uma nova fitodinâmica e levam, em geral, a uma regressão do potencial biológico dessas unidades, incluindo os povoamentos faunísticos. Entre as causas mais frequentes de incêndios estão as queimadas agrícolas em áreas vizinhas, a ação de piromaníacos, o comportamento irresponsável de transeuntes e a realização de cultos religiosos. Este trabalho inventariou todos os remanescentes florestais de Campinas-SP e elaborou um sistema de prevenção e combate a incêndios. Os resultados também estão disponíveis na Internet

Charon's radius and density from the combined data sets of the 2005 July 11 occultation

The 2005 July 11 C313.2 stellar occultation by Charon was observed by three separate research groups, including our own, at observatories throughout South America. Here, the published timings from the three data sets have been combined to more accurately determine the mean radius of Charon: 606.0 +/- 1.5 km. Our analysis indicates that a slight oblateness in the body (0.006 +/- 0.003) best matches the data, with a confidence level of 86%. The oblateness has a pole position angle of 71.4 deg +/- 10.4 deg and is consistent with Charon's pole position angle of 67 deg. Charon's mean radius corresponds to a bulk density of 1.63 +/- 0.07 g/cm3, which is significantly less than Pluto's (1.92 +/- 0.12 g/cm3). This density differential favors an impact formation scenario for the system in which at least one of the impactors was differentiated. Finally, unexplained differences between chord timings measured at Cerro Pachon and the rest of the data set could be indicative of a depression as deep as 7 km on Charon's limb.Comment: 25 pages including 4 tables and 2 figures. Submitted to the Astronomical Journal on 2006 Feb 0

Buoyancy waves in Pluto's high atmosphere: Implications for stellar occultations

We apply scintillation theory to stellar signal fluctuations in the high-resolution, high signal/noise, dual-wavelength data from the MMT observation of the 2007 March 18 occultation of P445.3 by Pluto. A well-defined high wavenumber cutoff in the fluctuations is consistent with viscous-thermal dissipation of buoyancy waves (internal gravity waves) in Pluto's high atmosphere, and provides strong evidence that the underlying density fluctuations are governed by the gravity-wave dispersion relation.Comment: Accepted 18 June 2009 for publication in Icaru

Praziquantel coverage in schools and communities targeted for the elimination of urogenital schistosomiasis in Zanzibar: a cross-sectional survey

© 2015 Knopp et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The attached file is the published version of the article

Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary approach

ABSTRACT: BACKGROUND: Schistosomiasis is a parasitic infection that continues to be a major public health problem in many developing countries being responsible for an estimated burden of at least 1.4 million disability-adjusted life years (DALYs) in Africa alone. However, morbidity due to schistosomiasis has been greatly reduced in some parts of the world, including Zanzibar. The Zanzibar government is now committed to eliminate urogenital schistosomiasis. Over the next 3--5 years, the whole at-risk population will be administered praziquantel (40 mg/kg) biannually. Additionally, snail control and behaviour change interventions will be implemented in selected communities and the impact measured in a randomized intervention trial. METHODS: In this 5-year research study, on both Unguja and Pemba islands, urogenital schistosomiasis will be assessed in 45 communities with urine filtration and reagent strips in 4,500 schoolchildren aged 9--12 years annually, and in 4,500 first-year schoolchildren and 2,250 adults in years 1 and 5. Additionally, from first-year schoolchildren, a finger-prick blood sample will be collected and examined for Schistosoma haematobium infection biomarkers. Changes in prevalence and infection intensity will be assessed annually. Among the 45 communities, 15 were randomized for biannual snail control with niclosamide, in concordance with preventive chemotherapy campaigns. The reduction of Bulinus globosus snail populations and S. haematobium-infected snails will be investigated. In 15 other communities, interventions triggering behaviour change have been designed and will be implemented in collaboration with the community. A change in knowledge, attitudes and practices will be assessed annually through focus group discussions and in-depth interviews with schoolchildren, teachers, parents and community leaders. In all 45 communities, changes in the health system, water and sanitation infrastructure will be annually tracked by standardized questionnaire-interviews with community leaders. Additional issues potentially impacting on study outcomes and all incurring costs will be monitored and recorded. DISCUSSION: Elimination of schistosomiasis has become a priority on the agenda of the Zanzibar government and the international community. Our study will contribute to identifying what, in addition to preventive chemotherapy, needs to be done to prevent, control, and ultimately eliminate schistosomiasis, and to draw lessons for current and future schistosomiasis elimination programmes in Africa and elsewhere.Trial registrationISRCTN4883768

Spin vectors in the Koronis family: V. Resolving the ambiguous rotation period of (3032) Evans

A sidereal rotation counting approach is demonstrated by resolving an ambiguity in the synodic rotation period of Koronis family member (3032) Evans, whose rotation lightcurves' features did not easily distinguish between doubly- and quadruply-periodic. It confirms that Evans's spin rate does not exceed the rubble-pile spin barrier and thus presents no inconsistency with being a ~14-km reaccumulated object. The full spin vector solution for Evans is comparable to those for the known prograde low-obliquity comparably-fast rotators in the Koronis family, consistent with having been spun up by YORP thermal radiation torques.Comment: 8 pages, 6 figures, accepted for publication in Icaru

Universality of the Gunn effect: self-sustained oscillations mediated by solitary waves

The Gunn effect consists of time-periodic oscillations of the current flowing through an external purely resistive circuit mediated by solitary wave dynamics of the electric field on an attached appropriate semiconductor. By means of a new asymptotic analysis, it is argued that Gunn-like behavior occurs in specific classes of model equations. As an illustration, an example related to the constrained Cahn-Allen equation is analyzed.Comment: 4 pages,3 Post-Script figure